Results 131 to 140 of about 310,335 (273)

Novel Electroactive Therapeutic Platforms for Cardiac Arrhythmia Management

Advanced Science, EarlyView.
Electroactive platforms offer promising applications in cardiac arrhythmia. Based on their energy sources and mechanisms, electroactive platforms are categorized into i) direct electrical stimulation, ii) self‐powered electroactive systems, iii) physical stimuli‐mediated electroactive systems, and iv) conductive systems, and their applications in ...
Juwei Yang, Longfei Li, Yiran Hu, Zhou Li, Wei Hua   +4 more
wiley   +1 more source

Wiring the senses: Factors that regulate peripheral axon pathfinding in sensory systems

Developmental Dynamics, Volume 252, Issue 1, Page 81-103, January 2023., 2023
Abstract Sensory neurons of the head are the ones that transmit the information about the external world to our brain for its processing. Axons from cranial sensory neurons sense different chemoattractant and chemorepulsive molecules during the journey and in the target tissue to establish the precise innervation with brain neurons and/or receptor ...
Gemma Nomdedeu‐Sancho, Berta Alsina
wiley   +1 more source

Suppression of induced pluripotent stem cell generation by the p53–p21 pathway [PDF]

, 2009
Hyenjong Hong, Kazutoshi Takahashi, Tomoko Ichisaka, Takashi Aoi, Osami Kanagawa, Masato Nakagawa, Keisuke Okita, Shinya Yamanaka   +7 more
openalex   +1 more source

Microenvironmental Modulation for Therapeutic Efficacy of Extracellular Vesicles

Advanced Science, EarlyView.
Recent studies highlighted the heterogeneity of EVs and the influence of microenvironmental signals on their therapeutic efficacy. This review offers a comprehensive overview of strategies and mechanisms to optimize the therapeutic efficacy of EVs through physical, biochemical, and mechanical modulation.
Bilu Xiang, Shiying Zhang, Irene Shuping Zhao, Xueqi Gan, Yang Zhang   +4 more
wiley   +1 more source

Generation of functional human hepatic endoderm from human induced pluripotent stem cells [PDF]

, 2009
Gareth J. Sullivan, David C. Hay, In-Hyun Park, Judy Fletcher, Zara Hannoun, Catherine Payne, Donna Dalgetty, James R. Black, James A. Ross, Kay Samuel, Gang Wang, George Q. Daley, Je-Hyuk Lee, George M. Church, Stuart J. Forbes, John P. Iredale, Ian Wilmut   +16 more
openalex   +1 more source

Technical Challenges in Using Human Induced Pluripotent Stem Cells to Model Disease [PDF]

, 2009
Krishanu Saha, Rudolf Jaenisch
openalex   +1 more source

Integrating Aggregate Materials and Machine Learning Algorithms: Advancing Detection of Pathogen‐Derived Extracellular Vesicles

Aggregate, EarlyView.
Pathogen‐derived extracellular vesicle detection: theoretical insights and advanced methodologies: This review explores the theoretical foundations and practical applications of pEV detection, emphasizing the challenges and innovative strategies involving novel aggregate materials and machine learning for enhanced diagnostic accuracy.
Lihan Lai, Yun Su, Cong Hu, Zehong Peng, Wei Xue, Liang Dong, Tony Y. Hu   +6 more
wiley   +1 more source

FDNet: Frequency Domain Denoising Network For Cell Segmentation in Astrocytes Derived From Induced Pluripotent Stem Cells [PDF]

arXiv
Artificially generated induced pluripotent stem cells (iPSCs) from somatic cells play an important role for disease modeling and drug screening of neurodegenerative diseases. Astrocytes differentiated from iPSCs are important targets to investigate neuronal metabolism.
arxiv  

Designed Biomaterial‐Enhanced Cell Transplantation for Neural Tissue Engineering

Aggregate, EarlyView.
Biomaterials offer a promising solution for cell transplantation in the central nervous system by creating a protective environment that enhances cell survival, integration, and functional recovery in preclinical models of neurological disorders. ABSTRACT Cell transplantation therapy in the central nervous system is hindered by limited survival and ...
Yun Tang, Alice Le Friec, Menglin Chen, Di Sun   +3 more
wiley   +1 more source

Dendritic cells generated from induced pluripotent stem cells and by direct reprogramming of somatic cells

European Journal of Immunology, Volume 52, Issue 12, Page 1880-1888, December 2022., 2022
Somatic cells (fibroblasts, dendritic cells, T cells) are reprogrammed into induced pluripotent stem cells (iPS cells) with specific transcription factors. iPS cells are then differentiated into iPS cell‐derived DC (ipDC) with DC inducing cytokines. Fibroblasts are directly reprogrammed into induced DC (iDC) by DC specific transcription factors (direct
Niclas Flosdorf, Martin Zenke
wiley   +1 more source