Results 151 to 160 of about 390,247 (379)
The Promise of Human Induced Pluripotent Stem Cells in Dental Research
Stem Cells International, 2012 Induced pluripotent stem cell-based therapy for treating genetic disorders has become an interesting field of research in recent years. However, there is a paucity of information regarding the applicability of induced pluripotent stem cells in dental ...
Thekkeparambil Chandrabose Srijaya +5 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.The study introduces innovative 3D microtissues that replicate the glomerular filtration barrier of the kidney, offering a novel platform for understanding podocytopathies. These microtissues simulate the glomerulus's structure and dynamics, allowing for the modeling of podocyte injuries and drug testing.
Sara Buttό +5 more
wiley +1 more source
Scientific Reports, 2015 Transplantation of bone marrow mesenchymal stem cells (BM-MSCs) can protect cardiomyocytes against anthracycline-induced cardiomyopathy (AIC) through paracrine effects. Nonetheless the paracrine effects of human induced pluripotent stem cell-derived MSCs
Yuelin Zhang +15 more
semanticscholar +1 more source
Induced pluripotent stem cells and hepatic differentiation
Journal of the Chinese Medical Association, 2013 Induced pluripotent stem cells (iPSCs) are generated by reprogramming somatic cells to a pluripotent state by the introduction of specific factors. They can be generated from cells of different origins, such as fibroblasts, keratinocytes, hepatocytes, and blood.
Yueh Chien +9 more
openaire +3 more sources
Advanced Healthcare Materials, EarlyView.This review highlights recent advances in microfluidic technologies for modeling human aging and age‐related diseases. It explores how organ‐on‐chip platforms improve physiological relevance, enable rejuvenation strategies, facilitate drug screening, detect senescent cells, and identify biomarkers.
Limor Zwi‐Dantsis +5 more
wiley +1 more source
International Journal of Organ Transplantation Medicine, 2015 Background: In regenerative medicine, use of each of the mesenchymal stem cells derived from bone marrow, cord blood, and adipose tissue, has several cons and pros.
T Foroutan +4 more
doaj
The significance of induced pluripotent stem cells for basic research and clinical therapy [PDF]
, 2008 John R. Meyer
openalex +1 more source
Systematic optimization of human pluripotent stem cells media using Design of Experiments. [PDF]
, 2015 Human pluripotent stem cells (hPSC) are used to study the early stages of human development in vitro and, increasingly due to somatic cell reprogramming, cellular and molecular mechanisms of disease.
Chailangkarn, Thanathom +2 more
core +1 more source
Toxicological Sciences, 2015 Functional changes to cardiomyocytes are a common cause of attrition in preclinical and clinical drug development. Current approaches to assess cardiomyocyte contractility in vitro are limited to low-throughput methods not amenable to early drug ...
A. Pointon +6 more
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.Through tuning biomimetic scaffold stiffness and matrix composition the reparative capacity of astrocyte progenitors is enhanced. Soft, collagen‐IV/fibronectin‐functionalized scaffolds promote progenitor growth while improving angiogenic, immunomodulatory, and neurotrophic capacity in a stiffness and matrix‐dependent manner, demonstrating the impact of
Cian O'Connor +10 more
wiley +1 more source