Results 161 to 170 of about 390,247 (379)

Generation of an induced pluripotent stem cell line SDPHi002-A from a patient with lung cancer

open access: yesStem Cell Research, 2023
Here, an induced pluripotent stem cell (iPSC) line from a patient with lung neuroendocrine carcinoma was generated. The iPSCs were developed using nonintegrating episomal vectors carrying OCT4, SOX2, KLF4, BCL-XL and c-MYC.
Dan Ai   +6 more
doaj  

Allele-specific NKX2-5 binding underlies multiple genetic associations with human electrocardiographic traits. [PDF]

open access: yes, 2019
The cardiac transcription factor (TF) gene NKX2-5 has been associated with electrocardiographic (EKG) traits through genome-wide association studies (GWASs), but the extent to which differential binding of NKX2-5 at common regulatory variants contributes
Benaglio, Paola   +17 more
core  

Integration of Bioengineered Tools in Assisted Reproductive Technologies

open access: yesAdvanced Healthcare Materials, EarlyView.
A conceptual illustration depicting the collaboration between a medical professional (right) and a scientist (left). Their connection highlights the integration of scientific research and clinical practice. This representation underscores the role of emerging technologies in bridging fundamental research with applied reproductive healthcare.
Aslı Ak   +3 more
wiley   +1 more source

Engineering a Human‐Sized Common Bile Duct Prototype with Regenerative Potential: In Vitro Evaluation of Mechanics, Function, Degradation, and Immune Modulation

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents a multiphasic bile duct construct composed of biocompatible materials and cells, featuring an inner layer that supports biliary epithelium growth, a middle layer providing mechanical strength, and an outer cell‐permissive layer designed to support future in vivo integration.
Mattia Pasqua   +9 more
wiley   +1 more source

Generation of induced pluripotent stem cell line (ZZUi011-A) from urine sample of a normal human

open access: yesStem Cell Research, 2018
Urine cells collected from 200 mL clean midsection urine of a 25-year-old healthy man were reprogrammed into pluripotent stem cells via Sendai virus delivery system. The induced pluripotent stem cells showed a normal karyotype and exhibited the potential
Huifang Sun   +6 more
doaj  

Therapeutic effects of induced pluripotent stem cells in chimeric mice with β-thalassemia

open access: yesHaematologica, 2014
Although β-thalassemia is one of the most common human genetic diseases, there is still no effective treatment other than bone marrow transplantation.
Guanheng Yang   +7 more
doaj   +1 more source

Induced Pluripotent Stem Cells Generated Without Viral Integration [PDF]

open access: green, 2008
Matthias Stadtfeld   +4 more
openalex   +1 more source

Materials Advances in Devices for Heart Disease Interventions

open access: yesAdvanced Materials, EarlyView.
This review examines the crucial role of materials in heart disease interventions, focusing on strategies for monitoring, managing, and repairing heart conditions. It discusses the material requirements for medical devices, highlighting recent innovations and their impact on cardiovascular health.
Gagan K. Jalandhra   +11 more
wiley   +1 more source

Induced pluripotent stem cell line (PEIi003-A) derived from an apparently healthy male individual

open access: yesStem Cell Research, 2020
Induced pluripotent stem cells (iPSCs) are a useful tool to investigate pathomechanistic and cellular processes due to their differentiation potential into different somatic cell types in vitro.
Nina V. Fuchs   +7 more
doaj  

Engineering Cellular Self‐Adhesions Inside 3D Printed Micro‐Arches to Enhance Cell:Biomaterial Attachment

open access: yesAdvanced Materials, EarlyView.
Surprisingly, a cell can bind to itself to make a self‐adhesion, which engineered here to improve how cells attach to biomaterials. Nanoprinting are used to make 3D structures smaller than cells–called Self‐Adhesion‐Tunnels (SATs)–around which cells can wrap and bind to themselves.
Anamika Singh   +4 more
wiley   +1 more source

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