Results 171 to 180 of about 390,247 (379)

Cell fiber-based three-dimensional culture system for highly efficient expansion of human induced pluripotent stem cells

open access: yesScientific Reports, 2017
Human pluripotent stem cells are a potentially powerful cellular resource for application in regenerative medicine. Because such applications require large numbers of human pluripotent stem cell-derived cells, a scalable culture system of human ...
Kazuhiro Ikeda   +3 more
doaj   +1 more source

Multimodal Platforms for Light‐Mediated Organic Bioelectronics

open access: yesAdvanced Materials Interfaces, EarlyView.
Optobioelectronic devices are paving the way for different types of interfacing with cells, in addition to classical electrical interfacing. Here, a future perspective for research in this field is discussed, in which different classes of light‐responsive materials are combined to create a highly dynamic interface that truly integrates with biological ...
Giovanna Gentile   +4 more
wiley   +1 more source

Generation and characterization of a human induced pluripotent stem cell line (SDQLCHi052-A) from peripheral blood mononuclear cells derived from a healthy Chinese donor

open access: yesStem Cell Research, 2023
A non-integrated induced pluripotent stem cell (iPSC) line was generated derived from a healthy 20-day-old male using peripheral blood mononuclear cells.
Zirui Wan   +8 more
doaj  

Enhanced efficiency of generating induced pluripotent stem (iPS) cells from human somatic cells by a combination of six transcription factors [PDF]

open access: bronze, 2008
Jing Liao   +14 more
openalex   +1 more source

Advances in Microfluidic Cochlea‐On‐A‐Chip

open access: yesAdvanced Science, EarlyView.
This review systematically examines diverse cell sources for inner ear organoids and outlines stepwise induction protocols. Furthermore, it discusses current applications and prospective developments of cochlea‐on‐a‐chip technologies in areas such as deafness modeling, mechanistic studies, and drug evaluation, with particular focus on gene‐therapy drug
Tian Shen   +10 more
wiley   +1 more source

Generation of three isogenic human induced pluripotent stem cell lines from normal neonate skin fibroblasts

open access: yesStem Cell Research
Characterized human induced pluripotent stem cell lines are important for basic research. Here, we report the establishment of three isogenic human induced pluripotent stem cell (hiPSC) lines generated from normal neonate male skin fibroblasts ...
Sanne Sandelin   +3 more
doaj  

Generation of Induced Pluripotent Stem Cell Lines from Adult Rat Cells [PDF]

open access: bronze, 2008
Jing Liao   +10 more
openalex   +1 more source

Stereotyped Subclones Revealed by High‐Density Single‐Cell Lineage Tracing Support Robust Development

open access: yesAdvanced Science, EarlyView.
Based on a well‐established in vitro directed differentiation model and an integrated analysis of high‐density cell lineage trees (CLTs) and single‐cell transcriptomes, it is demonstrated that many subclones are formed by sub‐CLTs resembling each other in terms of both cell type compositions and topological structures.
Xiaoyu Zhang   +14 more
wiley   +1 more source

The Morphological, Behavioral, and Transcriptomic Life Cycle of Anthrobots

open access: yesAdvanced Science, EarlyView.
DNA is thought to determine shape, behavior, and lifespan, with developmental plasticity reserved for stem cells, embryos, and species like amphibia. How much morphogenetic plasticity do adult somatic human cells exhibit? Anthrobots are a self‐organizing, motile synthetic living construct made of genetically normal human epithelial cells.
Gizem Gumuskaya   +6 more
wiley   +1 more source

Novel Adult-Onset Systolic Cardiomyopathy Due to MYH7 E848G Mutation in Patient-Derived Induced Pluripotent Stem Cells

open access: yesJACC: Basic to Translational Science, 2018
Summary: A novel myosin heavy chain 7 mutation (E848G) identified in a familial cardiomyopathy was studied in patient-specific induced pluripotent stem cell–derived cardiomyocytes.
Kai-Chun Yang, MD   +15 more
doaj  

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