Results 251 to 260 of about 223,235 (338)

Establishment of Interspecies Somatic Cell Nuclear Transfer and Transgene‐Free Inducible Pluripotent Stem Cells for Versatile Conservation of the Germplasm Resource of Wild Boar

Animal Research and One Health, EarlyView.
Conserving genetic material and even increasing genetic diversity is critical. To conduct the conservation of wild boar germplasm resources, we have successfully obtained healthy cloned wild boars for the first time using interspecies somatic cell nuclear transfer and established transgene‐free iPSCs that can be used to conduct iterative rounds of gene
Chen Gao, Xinyi Zhou, Shigang Gu, Jianbo Li, Jing Wang, Yurong Zhang, Wenxuan Zhao, Xinhua Wei, Liting Lu, Quanmin Zhao, Yongye Huang, Dawei Yu   +11 more
wiley   +1 more source

A comprehensive analysis of induced pluripotent stem cell (iPSC) production and applications. [PDF]

Front Cell Dev Biol
Matiukhova M, Ryapolova A, Andriianov V, Reshetnikov V, Zhuravleva S, Ivanov R, Karabelsky A, Minskaia E.   +7 more
europepmc   +1 more source

Modeling Choroideremia Disease with Isogenic Induced Pluripotent Stem Cells

Ana Fragoso Fonseca, Rita Coelho, Mafalda Lopes- da-Silva, Luísa de Lemos, Michael J. Hall, Daniela Oliveira, Ana S. Falcão, Sandra Tenreiro, Miguel C. Seabra, Pedro Antas   +9 more
openalex   +2 more sources

An Integrative approach to study mental illness through the resources of patient ???specific Human Induced pluripotent stem cells(HiPSCs) [PDF]

, 2020
Geetha M. Swamilingiah
openalex  

Linezolid prevents fibroblast activation and ameliorates tissue fibrosis by inhibition of mitochondrial translation

Arthritis &Rheumatology, Accepted Article.
Background Beyond its role as a ribosome‐targeting antibiotic, linezolid was recently shown to modulate immune responses by inhibiting mitochondrial translation. Since mitochondrial dysfunction is implicated in various fibrotic diseases, including systemic sclerosis (SSc), this study aimed to evaluate the antifibrotic potential of linezolid and ...
Xuezhi Hong, Yanhua Xiao, Haodong Qi, Shihao Zhu, Tim Filla, Andrea‐Hermina Györfi, Yi‐Nan Li, Meilin Xu, Langxian Zhi, Thuong Trinh‐Minh, Clara Dees, Georg Schett, Jörg H.W. Distler, Alexandru‐Emil Matei   +13 more
wiley   +1 more source

Generation of human induced pluripotent stem cell lines derived from Wolf-Hirschhorn syndrome patients with chromosomal 4p deletion. [PDF]

Hum Cell
Shimizu T, Takami M, Matsuo-Takasaki M, Noguchi M, Nakamura Y, Hayata T, Hayashi Y.   +6 more
europepmc   +1 more source

Hydrogel Embedding of Mesenchymal Stem Cells Supports Extracellular Vesicle Production

Biotechnology and Bioengineering, EarlyView.
This study investigates the effects of 3D culture conditions on extracellular vesicle (EV) production by mesenchymal stem cells (MSCs) in a gelatin‐based hydrogel matrix (GelMA). The EVs from both conditions were found to have similar morphological, molecular, and functional properties, but 3D cultures produced more total EVs per volume.
Rachel K. Moen, Gabriella Faircloth, Nicole T. Marguerite, Mariachiara Conti, Ethan S. Lippmann, Jamey D. Young   +5 more
wiley   +1 more source

CRISPR‐Cas9‐Based Genome Editing of Human Induced Pluripotent Stem Cells

, 2018
Joseph C. Giacalone, Tasneem P. Sharma, Erin R. Burnight, John H. Fingert, Robert F. Mullins, Edwin M. Stone, Budd A. Tucker   +6 more
openalex   +2 more sources