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Stem Cells, Induced Pluripotent
2021Induced pluripotent stem cells (iPSCs) refer to a type of stem cell directly generated using reprogramming techniques from multipotent adult stem cells. Therefore iPSCs gained a lower level of differentiation and could present themselves as pluripotent.
Henk ten Have +1 more
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Generation of Induced Pluripotent Stem Cells
2014Induced pluripotent stem cells (iPSCs) are generated from somatic cells that have been reprogrammed by the ectopic expression of defined embryonic transcription factors. This technology has provided investigators with a powerful tool for modeling disease and developing treatments for human disorders.
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Generation of Induced Pluripotent Stem Cells in Rabbits
2014We describe a procedure for generating induced pluripotent stem cell lines in rabbits, using retroviral vectors expressing Oct4, Sox2, Klf4, and c-Myc of human origin to reprogram rabbit fibroblasts prepared from an ear skin biopsy. We also provide detailed procedures for characterizing the resulting iPSC lines, including the analysis of pluripotency ...
Afanassieff, Marielle +2 more
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A safer stem cell: inducing pluripotency
Nature Medicine, 2009Laura, Clarke, Derek, van der Kooy
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A reference human induced pluripotent stem cell line for large-scale collaborative studies
Cell Stem Cell, 2022Justin A McDonough +2 more
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Induced pluripotent stem cells: the new patient?
Nature Reviews Molecular Cell Biology, 2012Milena Bellin +2 more
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Pluripotent stem cells progressing to the clinic
Nature Reviews Molecular Cell Biology, 2016Alan Trounson
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Induced pluripotent stem cells — opportunities for disease modelling and drug discovery
Nature Reviews Drug Discovery, 2011George Q Daley
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The promise of induced pluripotent stem cells in research and therapy
Nature, 2012George Q Daley
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