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A comprehensive analysis of induced pluripotent stem cell (iPSC) production and applications. [PDF]

Front Cell Dev Biol
Matiukhova M, Ryapolova A, Andriianov V, Reshetnikov V, Zhuravleva S, Ivanov R, Karabelsky A, Minskaia E.   +7 more
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Generation of two induced pluripotent stem cell lines from dilated cardiomyopathy patients harbouring TTN mutations. [PDF]

Stem Cell Res
Tan R, Chen YI, Zha Y, Herron T, Haddad F, Sallam K, Wu JC.   +6 more
europepmc   +1 more source

Optimisation of lytic herpes simplex virus infection in human induced pluripotent stem cell derived cortical neurones

Nash DA, Nicholson AS, Barrow HG, Connor V, Crump CM, Deane JE, Graham SC.   +6 more
europepmc   +1 more source

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Induced pluripotent stem cells

Russian Journal of Genetics, 2009
Induced pluripotent stem cells (iPS) result from a reprogramming of somatic cells via transduction with viral vectors expressing the Oct4, Sox2, c-Myc, Klf4, Nanog, and Lin28 genes, which are essential for the establishment and maintenance of the pluripotent state. In properties, iPS are almost fully similar to embryonic stem cells (ESC).
A I, Shevchenko, S P, Medvedev, N A, Mazurok, S M, Zakiian   +3 more
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Induced Pluripotent Stem Cells

2010
Reprogramming of mouse and human somatic cells into induced pluripotent stem (iPS) cells has been possible with retroviral expression of the pluripotency-associated transcription factors Oct4, Sox2, Nanog, and Lin28 as well as Klf4 and c-Myc. iPS cells hold great potential as a model for diseases from the perspective of the individual patient and as an
Zaehres, Holm, Kim, Jeong Beom, Scholer, Hans R.   +2 more
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Livestock Induced Pluripotent Stem Cells

Reproduction in Domestic Animals, 2012
ContentsChimeric animals generated from livestock‐induced pluripotent stem cells (iPSCs) have opened the door of opportunity to genetically manipulate species for the production of biomedical models, improving traits of agricultural importance and potentially providing a system to test novel iPSC therapies.
Y, Lu, J L, Mumaw, F D, West, S L, Stice
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Induced Pluripotent Stem Cells

2022
A limiting factor for the identification of disease mechanisms and development of new therapies has been the access to a model system/s that can faithfully recapitulate key features of the disease and more precise clinical translations of new treatments.
Ambrin Fatima, Uzma Abdullah, Zafar Ali
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Routes to induced pluripotent stem cells

Current Opinion in Genetics & Development, 2014
The generation of induced pluripotent stem cells (iPSCs) with Oct4, Sox2, Klf4, c-Myc has been described as 'direct' reprogramming in contrast to reprogramming via nuclear transfer. Interestingly, recent studies have suggested that the conversion process itself includes transient up-regulation and down-regulation of hundreds of genes, making unique ...
Tyson Ruetz, Keisuke Kaji
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Mouse-Induced Pluripotent Stem Cells

2012
Pluripotent stem cells belong to a unique population of cells, which can self-renew indefinitely and have the potential to give rise to all cell types in an organism. Generally, pluripotent stem cells include embryonic stem cells (ESCs), embryonic germ cells (EGCs), and embryonal carcinoma cells (ECCs) (Boiani and Scholer 2005).
Hui, Zhang, Ying, Jin
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