Results 81 to 90 of about 310,335 (273)

The Promise of Human Induced Pluripotent Stem Cells in Dental Research

open access: yesStem Cells International, 2012
Induced pluripotent stem cell-based therapy for treating genetic disorders has become an interesting field of research in recent years. However, there is a paucity of information regarding the applicability of induced pluripotent stem cells in dental ...
Thekkeparambil Chandrabose Srijaya   +5 more
doaj   +1 more source

Materials Advances in Devices for Heart Disease Interventions

open access: yesAdvanced Materials, EarlyView.
This review examines the crucial role of materials in heart disease interventions, focusing on strategies for monitoring, managing, and repairing heart conditions. It discusses the material requirements for medical devices, highlighting recent innovations and their impact on cardiovascular health.
Gagan K. Jalandhra   +11 more
wiley   +1 more source

How germline genes promote malignancy in cancer cells

open access: yesBioEssays, Volume 45, Issue 1, January 2023., 2023
We hypothesize that activation of a “germline program” promotes oncogenesis. Expression of otherwise germline specific genes may result in pseudomeiotic activity, thereby promoting oncogenesis through genomic instability. Other processes that are differentially regulated in the germline, such as migration and epigenetic – and metabolic plasticity, may ...
Jan Willem Bruggeman   +4 more
wiley   +1 more source

Transcription Factor-Mediated Generation of Dopaminergic Neurons from Human iPSCs—A Comparison of Methods

open access: yesCells
Dopaminergic neurons are the predominant brain cells affected in Parkinson’s disease. With the limited availability of live human brain dopaminergic neurons to study pathological mechanisms of Parkinson’s disease, dopaminergic neurons have been generated
Kirstin O. McDonald   +6 more
doaj   +1 more source

Modeling iPSC-derived Endothelial Cell Transition in Tumor Angiogenesis using Petri Nets [PDF]

open access: yesProceedings of the 17th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 1: BIOINFORMATICS, 337-346, 2024
Tumor angiogenesis concerns the development of new blood vessels supplying the necessary nutrients for the further development of existing tumor cells. The entire process is complex, involving the production and consumption of chemicals, endothelial cell transitions as well as cell interactions, divisions, and migrations.
arxiv   +1 more source

Aqueous Synthesis of Poly(ethylene glycol)‐Amide‐Norbornene‐Carboxylate for Modular Hydrogel Crosslinking

open access: yesAdvanced Materials Interfaces, EarlyView.
An all aqueous synthesis of poly(ethylene glycol)‐amide‐norbornene‐carboxylate (PEGaNBCA) is developed via reacting carbic anhydride with amino‐terminated PEG. PEGaNBCA is readily crosslinked into hydrogels by click chemistries. PEGaNBCA crosslinked thiol‐norbornene hydrogels are hydrolytically stable but can be rendered hydrolytically labile through ...
Nathan H. Dimmitt, Chien‐Chi Lin
wiley   +1 more source

Lower Oncogenic Potential of Human Mesenchymal Stem Cells Derived from Cord Blood Compared to Induced Pluripotent Stem Cells

open access: yesInternational Journal of Organ Transplantation Medicine, 2015
Background: In regenerative medicine, use of each of the mesenchymal stem cells derived from bone marrow, cord blood, and adipose tissue, has several cons and pros.
T Foroutan   +4 more
doaj  

The Role of Silicon Technology in Organ‐On‐Chip: Current Status and Future Perspective

open access: yesAdvanced Materials Technologies, EarlyView.
This review explores the potential of silicon micro‐nanofabrication technologies in advancing organ‐on‐chip systems. The integration of actuation and sensing modalities, highlight emerging technologies is discussed for combining silicon‐based and polymer‐based components, and emphasize the need for robust, high‐throughput, and customizable organ‐on ...
Frøydis Sved Skottvoll   +2 more
wiley   +1 more source

Induced Pluripotent Stem Cells Generated Without Viral Integration [PDF]

open access: green, 2008
Matthias Stadtfeld   +4 more
openalex   +1 more source

Advances in Microfluidic Cochlea‐On‐A‐Chip

open access: yesAdvanced Science, EarlyView.
This review systematically examines diverse cell sources for inner ear organoids and outlines stepwise induction protocols. Furthermore, it discusses current applications and prospective developments of cochlea‐on‐a‐chip technologies in areas such as deafness modeling, mechanistic studies, and drug evaluation, with particular focus on gene‐therapy drug
Tian Shen   +10 more
wiley   +1 more source

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