Results 291 to 300 of about 496,668 (364)

Somatic cell reprogramming for Parkinson's disease treatment

Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

Generation and characterization of giant panda induced pluripotent stem cells. [PDF]

Sci Adv
Liu Y, Zhang S, Zou G, An J, Li Y, Lin D, Wang D, Li Y, Chen J, Feng T, Li H, Chen Y, Zhang M, Kumar M, Wang L, Hou R, Liu J.   +16 more
europepmc   +1 more source

An Efficient Platform for Astrocyte Differentiation from Human Induced Pluripotent Stem Cells

bioRxiv, 2017
J. Tcw, Minghui Wang, A. A. Pimenova, Kathryn R Bowles, B. Hartley, Emre Lacin, S. Machlovi, Rawan Abdelaal, C. Karch, H. Phatnani, P. Slesinger, Bin Zhang, A. Goate, K. Brennand   +13 more
semanticscholar   +1 more source

The rise of 3D bioprinting advancements in modeling neurodegenerative diseases

Ibrain, EarlyView.
Modeling neurodegenerative diseases: 3D bioprinting as a strategy for replicating the complexity of brain architecture. Recent findings have demonstrated that 3D bioprinting platforms can be exploited to recreate the complex neural pattern, giving the possibility of controlling cell density and scaffold stiffness.
Lucia Iafrate, Gianluca Cidonio
wiley   +1 more source

The Role of Human-Induced Pluripotent Stem Cells in Studying Cardiac Channelopathies. [PDF]

Int J Mol Sci
Begovic M, Schneider L, Zhou X, Hamdani N, Akin I, El-Battrawy I.   +5 more
europepmc   +1 more source

Transcriptional repression of SOX2 by p53 in cancer cells regulates cell identity and migration

International Journal of Cancer, EarlyView.
What's New? SOX2 is one of the key developmental genes with a reported altered expression in many tumors. The mechanisms underlying SOX2 regulation in cancer, however, remain elusive. This study shows that TP53 transcriptionally regulates SOX2 through binding to its promoter and the SRR2 enhancer.
Patricia Lado‐Fernández, Jéssica M. Vilas, Tânia Fernandes, Carmen Carneiro, Sabela Da Silva‐Álvarez, Valentín Estévez‐Souto, Pablo Pedrosa, Miguel González‐Barcia, Luis E. Abatti, Jennifer A. Mitchell, Carmen Rivas, Gema Moreno‐Bueno, Anxo Vidal, Manuel Collado   +13 more
wiley   +1 more source

TAL1 overexpression in induced pluripotent stem cells promotes the formation of hematopoietic cell-forming complexes but inhibits enucleation <i>in vitro</i>. [PDF]

Front Cell Dev Biol
Shin A, Park SA, Kim JY, Baek EJ.
europepmc   +1 more source

Human induced pluripotent stem cells for modelling neurodevelopmental disorders

Nature Reviews Neurology, 2017
K. Ardhanareeswaran, J. Mariani, Gianfilippo Coppola, A. Abyzov, F. Vaccarino   +4 more
semanticscholar   +1 more source

Construction strategies for 3D printed cardiac tissue repair materials and their application potential

Interdisciplinary Medicine, EarlyView.
This article provides an overview of the construction strategies of 3D printing materials in cardiac tissue repair, focusing on personalized design, advanced printing technologies, and multi‐material integration. It showcases the application of carbon‐based, biomass‐based, and bio‐based composites.
Mingru Kong, Zhen Wu, Zeliang Zheng, Binrui Zhang, Yuting Zeng, Hao Deng, Dongyi Feng, Wenjun Zhang, Congru Li, Xiaodong Fu, Leyu Wang   +10 more
wiley   +1 more source

Shaking culture attenuates circadian rhythms in induced pluripotent stem cells during osteogenic differentiation through the TEAD-Fbxl3-CRY axis. [PDF]

Cell Death Discov
Fu Y, Okawa H, Vinaikosol N, Mori S, Limraksasin P, Nattasit P, Tahara Y, Egusa H.   +7 more
europepmc   +1 more source