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Induced Pluripotent Stem Cells — A Cautionary Note
New England Journal of Medicine, 2011There are two sources of the human pluripotent stem cell — the differentiated somatic cell, such as a skin fibroblast, and the embryo. Recent studies suggest that an extra level of caution is warranted in using stem cells derived from somatic cells.
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Generation of germline-competent induced pluripotent stem cells
Nature, 2007K. Okita, T. Ichisaka, S. Yamanaka
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Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts
Nature Biotechnology, 2008M. Nakagawa +9 more
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Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells
Science, 2007Junying Yu +11 more
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A safer stem cell: inducing pluripotency [PDF]
Nature Medicine, 2009 Derek van der Kooy, Laura Clarke
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Genome Editing in Induced Pluripotent Stem Cells using CRISPR/Cas9
Stem Cell Reviews and Reports, 2018Ronen Ben Jehuda, Y. Shemer, O. Binah
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Cardiac repair in guinea pigs with human engineered heart tissue from induced pluripotent stem cells
Science Translational Medicine, 2016F. Weinberger +14 more
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Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes
Nature Biotechnology, 2008T. Aasen +12 more
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