Results 61 to 70 of about 398,685 (377)
Integration-free induced pluripotent stem cells from related human donors’ exhibit great potential to the ongoing development of organ models. Blood cells from two different human donors were isolated, purified and reprogrammed into induced pluripotent ...
Anja Patricia Ramme+4 more
doaj
Background Ex vivo manufacture of red blood cells from stem cells is a potential means to ensure an adequate and safe supply of blood cell products. Advances in somatic cell reprogramming of human induced pluripotent stem cells have opened the door to ...
Hélène Lapillonne+13 more
doaj +1 more source
Differentiation of primate primordial germ cell-like cells following transplantation into the adult gonadal niche. [PDF]
A major challenge in stem cell differentiation is the availability of bioassays to prove cell types generated in vitro are equivalent to cells in vivo. In the mouse, differentiation of primordial germ cell-like cells (PGCLCs) from pluripotent cells was ...
Chen, Di+13 more
core +2 more sources
The ability of extracellular vesicles (EVs) to regulate a broad range of cellular processes has recently been exploited for the treatment of diseases.
Bohao Liu+14 more
semanticscholar +1 more source
Induced pluripotent stem cells in infections [PDF]
Regenerative medicine has an exciting role in the treatment of disorders and conditions where there is an irreversible damage to a tissue or an organ or in immunodeficient state. Stem cells which have the potential to differentiate into specific types of cells, offers a new concept of regenerative medicine to treat spectrum of diseases including ...
Usha Bhoria+2 more
openaire +1 more source
Therapeutic effects of induced pluripotent stem cells in chimeric mice with β-thalassemia
Although β-thalassemia is one of the most common human genetic diseases, there is still no effective treatment other than bone marrow transplantation.
Guanheng Yang+7 more
doaj +1 more source
Construction of 3D in vitro models by bioprinting human pluripotent stem cells: Challenges and opportunities [PDF]
Three-dimensional (3D) printing of biological material, or 3D bioprinting, is a rapidly expanding field with interesting applications in tissue engineering and regenerative medicine. Bioprinters use cells and biocompatible materials as an ink (bioink) to
Rosa, Alessandro, Salaris, Federico
core +1 more source
Induced pluripotent stem cells: An update [PDF]
Introduction: The discovery that the mature cells can be reprogrammed to become pluripotent increased the enormous interest in induced pluripotent stem cell (iPSC) technology for their potential application in biomedical sciences. The breakthrough research offering induction of pluripotent status in somatic cells by direct reprogramming depends upon ...
Usha Bhoria+2 more
openaire +1 more source
MicroRNAs are differentially expressed in cells and regulate multiple biological processes. We have been analyzing comprehensive expression patterns of microRNA in human and mouse embryonic stem and induced pluripotent stem cells. We determined microRNAs
Siti Razila Abdul Razak+4 more
doaj +1 more source
The potential and limitations of induced pluripotent stem cells to achieve wound healing
Wound healing is the physiologic response to a disruption in normal skin architecture and requires both spatial and temporal coordination of multiple cell types and cytokines. This complex process is prone to dysregulation secondary to local and systemic
Jolanta Gorecka+16 more
semanticscholar +1 more source