Results 91 to 100 of about 5,003,944 (244)

In situ characterisation of CD4+ t cell behaviour in mucosal and systemic lymphoid tissues during the induction of oral priming and tolerance [PDF]

, 2005
The behavior of antigen-specific CD4+ T lymphocytes during initial exposure to antigen probably influences their decision to become primed or tolerized, but this has not been examined directly in vivo.
Smith, Karen M, Zinselmeyer, BH, Zinselmeyer, Bernd H, Smith, KM, Rush, C.M., Rush, Catherine M., Michael Cahalan, Ho, H., Smith, K.M., Ian Parker, Wokosin, D, Rush, Catherine M, Cahalan, M., Cahalan, Michael, Miller, M., Dempster, J., Millington, OR, Gurney, Alison M.; id_orcid, Parker, I., Ho, Hsiang, Calahan, M., Mark Miller, Millington, Owain R., Parker, I, Rush, CM, Garside, P, Alison M. Gurney, Millington, Owain R, Bernd H. Zinselmeyer, Gurney, A.M., Dempster, J, Wokosin, D.L., Paul Garside, Owain R. Millington, Millington, O.R., Catherine M. Rush, Smith, Karen M., Wokosin, D., Hsiang Ho, Dempster, John, Karen M. Smith, John Dempster, Parker, Ian, Gurney, Alison M, Brewer, James M, Gurney, Alison M., Ho, H, Cahalan, M, Millington, A.R., Wokosin, David, Zinselmeyer, B.H., Zinselmeyer, B. H., Brewer, James M., Brewer, J.M., Miller, M, Gurney, AM, David Wokosin, Garside, P., Zinselmeyer, Bernd H., Miller, Mark, James M. Brewer, Garside, Paul, Brewer, JM   +62 more
core   +2 more sources

Plant Growth Promotion and Induction of Systemic Tolerance to Drought and Salt Stress of Plants by Quorum Sensing Auto-Inducers of the N-acyl-homoserine Lactone Type: Recent Developments

Frontiers in Plant Science, 2021
Anton Hartmann, Sophia Klink, Michael Rothballer   +2 more
doaj   +1 more source

Tumor-activated dual metabolic nanomodulator turns over tolerogenic tumor control and unleashes systemic immune responses

Journal of Nanobiotechnology
Temporary amelioration of immunosuppression following extrinsic stress-induced immunogenic signal release provides opportunities for immunotherapy improvement.
Xiaorong Kou, Xue Wu, Tao He, Liping Bai, Xinchao Li, Rui Luo, Yangsong Xu, Yixi Wang, Meiling Shen, Changyang Gong, Qinjie Wu   +10 more
doaj   +1 more source

Self‐Healing Hydrogel‐Enabled Modular Assembly of Bilayered Skin Construct for Hair Follicle Regeneration

Advanced Healthcare Materials, EarlyView.
Self‐healing assembly of two cell‐laden hydrogel layers creates a biomimetic skin construct that restores both dermal and epidermal functions, resulting in accelerated wound healing and enhanced hair follicle regeneration in a full‐thickness skin wound model. ABSTRACT Alopecia remains a pervasive clinical challenge, largely owing to the limited ability
JaeWook Park, Su Yong Kim, MinSu Jeong, Beom Joon Kim, Shin Hyuk Kang, Won‐Gun Koh   +5 more
wiley   +1 more source

Fault Tolerant Control for Uncertain Networked Control Systems With Induced Delays and Actuator Saturation

IEEE Access, 2016
The fault tolerant control problem is investigated for a class of uncertain networked control systems (NCSs) subject to actuator faults and actuator saturation in this paper. System parameter uncertainties are considered and a sector condition method is employed to deal with the saturation problem.
Luo Zhang 0003, Mou Chen, Qing-Xian Wu, Bei Wu   +3 more
openaire   +2 more sources

Atom‐Efficient Cerium‐Based Molecular Cages as Biocompatible Reactive Oxygen Scavengers

Advanced Healthcare Materials, EarlyView.
Discrete mixed‐valent cerium molecular cages organize accessible redox centers within confined coordination environments and scavenge superoxide, hydrogen peroxide, and hydroxyl radicals. Encapsulation of the lead cage in an ROS‐responsive DTP nanoplatform enables lesion‐associated delivery, attenuates macrophage oxidative stress and inflammation, and ...
Chao Li, Chunbai Xiang, Ye Xu, Yu Liu, Keze Hong, Fanchu Zeng, Gelin Xu, Zhao‐Xi Wang, Jonathan L. Sessler, Ping Gong   +9 more
wiley   +1 more source

Species-specific regulation of herbivory-induced defoliation tolerance is associated with jasmonate inducibility [PDF]

, 2017
Induced changes in root carbohydrate pools are commonly assumed to determine plant defoliation tolerance to herbivores. However, the regulation and species specificity of these two traits are not well understood.
Machado, R., Ferrieri, A., Xu, S., Ricardo A. R. Machado, Erb, M., Wenwu Zhou, Carla C.M. Arce, Baldwin, I., Matthias Erb, Zhou, Wenwu, Baldwin, Ian T., Ferrieri, Abigail P., Erb, Matthias, Abigail P. Ferrieri, Arce, C., Ian T. Baldwin, Arce, Carla C. M., Xu, Shuqing, Shuqing Xu, Machado, Ricardo A. R., Zhou, W., Arce CCM, Machado RAR, Baldwin IT, Ferrieri AP, Erb M, Zhou W, Xu S   +27 more
core   +2 more sources

Pressure‐Assisted Drug Delivery Using High‐Pressure Balloon Platform Improves Vascular Drug Penetration and Anti‐Restenotic Effects

Advanced Healthcare Materials, EarlyView.
A dual‐layer high‐pressure drug‐coated balloon (HP@DCB) increased balloon‐wall contact and promoted deeper paclitaxel (PTX) penetration than a conventional noncompliant DCB. In in vivo study, HP@DCB treatment improved luminal patency and reduced neointimal hyperplasia, supporting pressure‐assisted drug delivery as a promising strategy for enhancing the
Seung Jin Eo, So Yun Lim, Dong‐Sung Won, Ji Won Kim, Yubeen Park, Song Hee Kim, Hyemin Lee, Jung‐Min Ahn, Jun‐Kyu Park, Do‐Yoon Kang, Jung‐Hoon Park   +10 more
wiley   +1 more source

Modeling Early Metastatic Progression in Breast Cancer Using a Barrier‐Free, Perfusable Spheroid‐on‐a‐Chip Platform

Advanced Healthcare Materials, EarlyView.
Open‐port, barrier‐free microfluidic device for modeling early metastatic progression. A centrally positioned tumor spheroid releases invasive cells that migrate through the surrounding matrix and intravasate into endothelialized lateral channels.
Vira Sharko, Claudia Olaizola‐Rodrigo, Clara Bayona, Teodora Ranđelović, Rosa Monge, Estela Solanas, Sara Oliván, Ignacio Ochoa   +7 more
wiley   +1 more source

Bone Organoids Across the Development‐to‐Remodeling Continuum: From Tissue Formation to Functional Competence and Translation

Advanced Healthcare Materials, EarlyView.
Mineralization alone does not establish a mature bone organoid. This Review integrates biological foundations, materials design, adaptive remodeling, and translational validation through the development‐to‐remodeling continuum (DRC). By separating biological functions from the evidence supporting them, the framework exposes critical gaps in current ...
Xijie Tang, Haijia Xu, Xiangzhong Liu, Yi Yang, Zhanghua Li   +4 more
wiley   +1 more source