Results 101 to 110 of about 4,786,356 (294)

Water‐Soluble, Enzyme‐Degradable, and Hydrolyzable STAR Particles for Enhanced Drug Delivery to Skin

Advanced Healthcare Materials, EarlyView.
Biodegradable polymer STAR particles fabricated from water‐soluble, enzyme‐degradable, and hydrolyzable materials significantly enhance intradermal drug delivery. By replacing conventional non‐biodegradable materials, these STAR particles address environmental and safety concerns while expanding the potential of skin‐based drug delivery technologies ...
Aydin Sadeqi, Gülçin Arslan Azizoğlu, Mark R. Prausnitz   +2 more
wiley   +1 more source

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel   +8 more
wiley   +1 more source

A comparison of hydroponic and soil-based screening methods to identify salt tolerance in the field in barley [PDF]

, 2012
Success in breeding crops for yield and other quantitative traits depends on the use of methods to evaluate genotypes accurately under field conditions. Although many screening criteria have been suggested to distinguish between genotypes for their salt ...
McDonald, G., Fatehi, F., Tavakkoli, E., Rengasamy, P.   +3 more
core   +1 more source

Overcoming Photodynamic Therapy Resistance: GSH‐Responsive AIE Photosensitizer‐Hydroxycamptothecin Nanoliposomes for Extrahepatic Cholangiocarcinoma

Advanced Healthcare Materials, EarlyView.
A GSH‐responsive AIE nanoplatform (TSH NPs) with RGD‐mediated tumor targeting co‐delivers a photosensitizer (TPA) and HCPT for extrahepatic cholangiocarcinoma. The system synergistically enhances PDT and chemotherapy by suppressing HIF‐1α/VEGF‐driven hypoxic adaptation, effectively overcoming PDT resistance.
Yong Qu, Tao Peng, Yating Zhang, Juanmei Cao, Birong Wang, Chuxing Chai, Zhiyuan Gao, Yiting Xu, Yifan Jin, Yuqing Wang, Zhuoxia Li, Xu Liu, Tianqi Zhao, Yufan Chen, Weimin Lv, Di Lu, Changzheng Huang, Dan Ding, Jinxiang Zhang, Min Li   +19 more
wiley   +1 more source

Silica Exposure Differentially Modulates Autoimmunity in Lupus Strains and Autoantibody Transgenic Mice

Frontiers in Immunology, 2019
Inhalational exposure to crystalline silica is linked to several debilitating systemic autoimmune diseases characterized by a prominent humoral immune component, but the mechanisms by which silica induces autoantibodies is poorly understood.
Mary H. Foster, Mary H. Foster, Jeffrey R. Ord, Emma J. Zhao, Anastasiya Birukova, Lanette Fee, Lanette Fee, Francesca M. Korte, Yohannes G. Asfaw, Victor L. Roggli, Andrew J. Ghio, Robert M. Tighe, Robert M. Tighe, Amy G. Clark, Amy G. Clark   +14 more
doaj   +1 more source

How is Nanoarchitectonics Shaping Extracellular Vesicle Research?

Advanced Healthcare Materials, EarlyView.
The convergence of nanoarchitectonics and extracellular vesicle biology is reshaping next‐generation nanomedicine by enabling rationally designed nanostructures for enhanced EVs detection, engineering, and therapy. ABSTRACT Extracellular vesicles (EVs) have gained recognition as crucial mediators of cell‐to‐cell communication, holding immense potential
Madushani Dahanayake, Md Shahriar A. Hossain, Chia‐Hung Liu, Carlos Salomon, Yusuke Yamauchi, Mostafa Kamal Masud   +5 more
wiley   +1 more source

Biphasic Co‐Delivery of Curcumin and 5‐FU using 3D‐Printed Dissolving Microneedles for Skin Cancer Therapy

Advanced Healthcare Materials, EarlyView.
Using pixel‐aware digital light processing, the authors created high‐resolution, dissolvable microneedles from a PEGDA/VP matrix. These microneedles encapsulate curcumin and 5‐fluorouracil and dissolve in the skin, co‐delivering drugs directly to tumours.
Rutuja N. Meshram, Dimitrios A. Lamprou
wiley   +1 more source

Endurance and Resistance Training Affect High Fat Diet-Induced Increase of Ceramides, Inflammasome Expression, and Systemic Inflammation in Mice

Journal of Diabetes Research, 2016
The study aimed to investigate the effects of differentiated exercise regimes on high fat-induced metabolic and inflammatory pathways. Mice were fed a standard diet (ST) or a high fat diet (HFD) and subjected to regular endurance training (ET) or ...
Cornelia Mardare, Karsten Krüger, Gerhard Liebisch, Michael Seimetz, Aline Couturier, Robert Ringseis, Jochen Wilhelm, Norbert Weissmann, Klaus Eder, Frank-Christoph Mooren   +9 more
doaj   +1 more source

Fault Tolerant Control for Uncertain Networked Control Systems With Induced Delays and Actuator Saturation

IEEE Access, 2016
The fault tolerant control problem is investigated for a class of uncertain networked control systems (NCSs) subject to actuator faults and actuator saturation in this paper. System parameter uncertainties are considered and a sector condition method is employed to deal with the saturation problem.
Luo Zhang 0003, Mou Chen, Qing-Xian Wu, Bei Wu   +3 more
openaire   +2 more sources

Radiation-induced neuropathic pain successfully treated with systemic lidocaine administration

, 2018
A Ram Doo,1 Yu Seob Shin,2 Seonwoo Yoo,1 Jong Kwan Park2 1Department of Anesthesiology and Pain Medicine, 2Department of Urology, Chonbuk National University and Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research ...
Doo AR, Yoo S, Shin YS, Park JK
core