Results 101 to 110 of about 5,003,944 (244)

Silica Exposure Differentially Modulates Autoimmunity in Lupus Strains and Autoantibody Transgenic Mice

Frontiers in Immunology, 2019
Inhalational exposure to crystalline silica is linked to several debilitating systemic autoimmune diseases characterized by a prominent humoral immune component, but the mechanisms by which silica induces autoantibodies is poorly understood.
Mary H. Foster, Mary H. Foster, Jeffrey R. Ord, Emma J. Zhao, Anastasiya Birukova, Lanette Fee, Lanette Fee, Francesca M. Korte, Yohannes G. Asfaw, Victor L. Roggli, Andrew J. Ghio, Robert M. Tighe, Robert M. Tighe, Amy G. Clark, Amy G. Clark   +14 more
doaj   +1 more source

Soft and Transient Bioelectronics Enabled by Polymer‐Free Ti3C2Tx MXene Hydrogels

Advanced Materials, EarlyView.
We present Ti3C2Tx MXene hydrogel (MXgel) bioelectronics, a soft, flexible, and fully transient platform for high‐fidelity neural recording and stimulation. MXgel bioelectronics exhibit exceptional electrical conductivities, low electrochemical impedances, and high charge injection capacities.
Raghav Garg, Franco A. Laimo, Stefano Ippolito, Prastuti Upadhyay, Spencer R. Averbeck, Dimitris Boufidis, Charles‐Antoine Assenmacher, Dayo O. Adewole, Sai Panigrahy, Bita Soltan Mohammadlou, Lucy Plant, Yuan Zhang, Andrew G. Richardson, Yury Gogotsi, D. Kacy Cullen, Flavia Vitale   +15 more
wiley   +1 more source

Endurance and Resistance Training Affect High Fat Diet-Induced Increase of Ceramides, Inflammasome Expression, and Systemic Inflammation in Mice

Journal of Diabetes Research, 2016
The study aimed to investigate the effects of differentiated exercise regimes on high fat-induced metabolic and inflammatory pathways. Mice were fed a standard diet (ST) or a high fat diet (HFD) and subjected to regular endurance training (ET) or ...
Cornelia Mardare, Karsten Krüger, Gerhard Liebisch, Michael Seimetz, Aline Couturier, Robert Ringseis, Jochen Wilhelm, Norbert Weissmann, Klaus Eder, Frank-Christoph Mooren   +9 more
doaj   +1 more source

Bacteria‐Trained, MnO2‐Armored Dendritic Cells for Immunotherapy

Advanced Materials, EarlyView.
MnO2‐armored, bacteria‐trained dendritic cells undergo tumor‐responsive mechanical and immunological transformation. The nanocoating masks immune ligands and maintains a mechanically stiff, quiescent state during circulation, while the tumor microenvironment removes the armor and restores cellular deformability and immune accessibility.
Zhao Guo, Min Ge, Zesong Ruan, Tingwang Shi, Mahyar Mahmoudi, Soohwan An, Na Kong, Yunfeng Chen, Han Lin, Wei Tao   +9 more
wiley   +1 more source

A root-associated Bacillus albus LRS2 and its metabolites for plant growth promotion and drought stress tolerance in little millet (Panicum sumatrense L.)

Plant Stress
The exploitation of drought-tolerant plant-associated bacteria in sustainable agriculture is considered potential for boosting plant growth and development under adverse environments featured by low water potentials.
Monisha Rajkumar, Shobana Narayanasamy, Sivakumar Uthandi   +2 more
doaj   +1 more source

CD3-specific antibody-induced immune tolerance involves transforming growth factor-beta from phagocytes digesting apoptotic T cells.

, 2008
International audienceIntact CD3-specific antibody transiently depletes large numbers of T cells and subsequently induces long-term immune tolerance. The underlying mechanisms for the systemic tolerance, however, remain unclear.
Perruche, Sylvain, Philippe Saas, Chen, Wanjun, Sylvain Perruche, Yongzhong Liu, Jeffrey A Bluestone, WanJun Chen, Saas, Philippe, Liu, Yongzhong, Zhang, Pin, Pin Zhang, Bluestone, Jeffrey, A.   +11 more
core   +1 more source

GaSex Nanoparticles Modulate Neutrophil Function and Mitigate NET‐Driven Osteogenic Impairment in Osteomyelitis Therapy

Advanced Materials, EarlyView.
Neutrophil extracellular traps (NETs) emerge as a critical repair‐limiting factor in osteomyelitis, driving osteoblast mitochondrial dysfunction and excessive PINK1/Parkin‐mediated mitophagy. Gallium–selenium nanoparticles (GaSex) scavenge reactive oxygen species, redirect neutrophils from NETosis toward bactericidal phagocytosis, eliminate methicillin‐
Kai Ye, Xuanzhe Liu, Zifan Pei, Chenyi Jiang, Xiaofen Zhang, Lin Lin, Qihang Fang, Binyu Chen, Longxiang Shen, Liang Cheng, Peng Ding, Xianyou Zheng   +11 more
wiley   +1 more source

Plant growth promoting signatory volatiles emitted by a drought-tolerant bacterium Bacillus altitudinis FD48 and its role in moisture stress alleviation in rice (Oryza sativa L.)

Plant Stress
Increasing evidence implies that bacterial volatile organic compounds (bVOCs) play a significant role in plant-microbe interaction. Plant associated bacteria produces plant growth modulating volatiles elicits induced systemic tolerance (IST) in plants ...
Shobana Narayanasamy, Sivakumar Uthandi
doaj   +1 more source

“Activation‐Resistance Elimination” Regulation by Lanthanide/Transition Metal Ion‐Coordinated Nanostructures Intensifies Cuproptosis and Tumor Immunotherapy

Advanced Materials, EarlyView.
The lanthanide/transition metal ion coordination nanoparticles, La‐Cu@Lap/IWR‐1, with optimized coordination, have been proven to achieve remarkable results in realizing comprehensive tumor cuproptosis through efficient cuproptosis activation and multidimensional resistance elimination, thereby synchronously realizing the synergistic antitumor effects ...
Junrong Wang, Mengqian Xu, Huaping Zhao, Yulin Xie, Guoqing Zhu, Haoze Li, Qianqian Sun, Yong Lei, Chunxia Li   +8 more
wiley   +1 more source

Beyond Passivation: Designing Structurally Tailored Artificial Interphases for High‐Energy Lithium‐Based Anodes

Advanced Materials Interfaces, EarlyView.
This review outlines critical engineering design rules for building artificial protective coatings on next‐generation lithium metal and silicon battery anodes. It highlights how balancing structural flexibility with strict electronic and ionic transport limits prevents early battery failure.
Surin Gupte, Vilas G. Pol
wiley   +1 more source