Results 251 to 260 of about 4,786,356 (294)
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Systemic Rapamycin Attenuates Morphine-Induced Analgesic Tolerance and Hyperalgesia in Mice
Neurochemical Research, 2018Previous studies showed that repeated intrathecal morphine injection activated the mammalian target of rapamycin complex 1 (mTORC1) in spinal dorsal horn neurons and that blocking this activation by intrathecal infusion of rapamycin, a specific mTORC1 inhibitor, prevented the initiation of morphine-induced tolerance and hyperalgesia. However, in clinic,
Xin Qi
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Brain Research, 1987
The acquisition and retention of tolerance to the antinociceptive effect of supraspinal morphine on the tail withdrawal reflex was assessed in rats implanted with unilateral cannulae in the periaqueductal gray (PAG). Development of tolerance to daily microinjections of morphine was indicated by the return of the tail flick response within 4 days ...
J A, Siuciak, C, Advokat
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The acquisition and retention of tolerance to the antinociceptive effect of supraspinal morphine on the tail withdrawal reflex was assessed in rats implanted with unilateral cannulae in the periaqueductal gray (PAG). Development of tolerance to daily microinjections of morphine was indicated by the return of the tail flick response within 4 days ...
J A, Siuciak, C, Advokat
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Spinal antagonism of tolerance and dependence induced by systemically administered morphine
European Journal of Pharmacology, 1983We observed that the spinal cord of rats was involved in development of tolerance and dependence to morphine that was administered systemically by s.c. morphine-pellet implantation. Rats, surgically fitted with intrathecal catheters, were injected intrathecally (i.t.) with saline or 2.4 nmol beta-chlornaltrexamine (beta-CNA), an irreversible opiate ...
G E, Delander, A E, Takemori
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Mucosal T Cells Induce Systemic Anergy for Oral Tolerance
Biochemical and Biophysical Research Communications, 1995Heat-labile enterotoxin (LT) from enterotoxigenic Escherichia coli is known to possess strong immunoregulatory potential in terms of inhibition of the induction of oral tolerance and adjuvanticity in oral immunization. We found that oral administration of an immunogenic peptide of LT [LT-B(26-45); spanning the residues 26-45 of LT-B] induced systemic ...
I, Takahashi +5 more
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Lack of tolerance to ethanol-induced stimulation of mesolimbic dopamine system.
Alcohol and alcoholism (Oxford, Oxfordshire), 1992Rats maintained for 10 days on a 10% ethanol solution as the sole source of fluid developed marked tolerance to ethanol-induced loss of righting reflex, but no tolerance to the stimulatory effects on mesolimbic dopaminergic system. An ethanol challenge stimulated both the electrical activity of A10 dopaminergic cells and dopamine output in the ventral ...
DIANA, Marco, GESSA GL, ROSSETTI ZL
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Drought-tolerant Bacillus megaterium isolated from semi-arid conditions induces systemic tolerance of wheat under drought conditions [PDF]
Plant Cell Reports, 2021 A detailed study of the response of wheat plants, inoculated with drought-tolerant PGPR is studied which would be beneficial to achieve genetic improvement of wheat for drought tolerance. Drought stress, a major challenge under current climatic conditions, adversely affects wheat productivity.
Urooj Rashid +11 more
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Role of dopaminergic systems in tolerance to neuroleptic-induced inhibition of food consumption
Neuropharmacology, 1978Abstract Male rats were trained to consume their daily ration of food in 2 hr of food availability. Benperidol, haloperidol and pimozide inhibited feeding elicited in this manner. Azaperone. chlorpromazine and phenoxybenzamine showed only weak activity.
M D, Hynes, D, Valentino, H, Lal
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Volatile cinnamaldehyde induces systemic salt tolerance in the roots of rice (Oryza sativa)
Physiologia Plantarum, 2023AbstractCinnamaldehyde (CA) is a volatile plant secondary metabolite that exhibits strong anti‐pathogenic activities. Nonetheless, less is known about the effect of CA on plant tolerance to abiotic stresses. In this study, we delineated the effects of CA fumigation on rice roots (Oryza Sativa L cv. TNG67) under salinity stress (200 mM NaCl). Our result
Chung‐Chih Huang +7 more
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Temperature acclimation: Temperature shift induces system conversion to cold tolerance in C. elegans
Neuroscience Research, 2023Acclimation to temperature is one of the survival strategies used by organisms to adapt to changing environmental temperatures. Caenorhabditis elegans' cold tolerance is altered by previous cultivation temperature, and similarly, past low-temperature induces a longer lifespan.
Akane Ohta +2 more
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[Tolerance to induced systemic hyperthermia in the mouse].
Comptes rendus des seances de la Societe de biologie et de ses filiales, 1986The effect of exposure of organisms to systemic hyperthermia on induction of tolerance to the lethal effect of subsequently assigned systemic hyperthermia was studied in mice. The length of time of the pretreatment at 42.0 +/- 0.2 degrees C (core body temperature) was 5, 10 or 15 mn.
W, Nakamura, K, Komatsu
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