Results 91 to 100 of about 1,458,680 (306)
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Descripción anestesiológica del efecto de un protocolo en base a Azaperona y Ketamina en conejo doméstico (oryctolagus cuniculus) [PDF]
, 2007 The effects of the anaesthetic protocol, based on a premedication with atropine and azaperone (Stresnil ®) and the anesthetic induction with a 0.5% ketamine solution, were studied in 25 healthy adults rabbits.Each animal was premed with 0.04 mg/kg b.w ...
Bastías, Andrés +4 more
core +2 more sources
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
transient phase (induction period)
, 2014 Citation: 'transient phase (induction period)' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.T06450 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms ...
openaire +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Induction of lactation in dairy heifers: milk production, inflammatory and metabolic aspects [PDF]
Arquivo Brasileiro de Medicina Veterinária e ZootecniaThe aim of this study was to evaluate the metabolic, inflammatory, and hepatic aspects, as well as the milk yield in heifers submitted to protocol for induction of lactation compared to primiparous cows.
G.B. Luz +5 more
doaj +2 more sources
Creating an iPod library tour [PDF]
, 2006 [FIRST PARAGRAPH] Over the years, traditional tours of the Main Library for new students had become unviable, primarily because of the huge numbers of students on many programmes and the short induction period.
Mawson, Maria +2 more
core
Theory of Magnetic Field Induced Spin Density Wave in High Temperature Superconductors
, 2002 The induction of spin density wave (SDW) and charge density wave (CDW) orderings in the mixed state of high $T_c$ superconductors (HTS) is investigated by using the self-consistent Bogoliubov-de Gennes equations based upon an effective model Hamiltonian ...
B. Lake +17 more
core +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Physical and Chemical Aspects of the Nucleation of Cement-Based Materials
Acta Polytechnica, 2012 A theoretical model of the nucleation of portlandite is proposed, and the critical size of a portlandite cluster and the energy barrier of nucleation are determined.
Pavel Demo +4 more
doaj