Results 71 to 80 of about 727,944 (302)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
, 2011 This dissertation consists of three interrelated sections dealing with: (i) Development of a suitable seed preparation technique, (ii) Determination of growth and aggregation kinetics and (iii) Determination of the induction ...
Musil, Emily Ann
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Improved induction motors as part of variable speed drive of turbomechanisms
Известия высших учебных заведений: Проблемы энергетики, 2017 In this paper, the authors discuss the main features of turbo mechanisms based on improved induction motors for usage as a part of variable speed drive.
P. V. Tyuteva, E. V. Beyerleyn
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Theory evaluation of the touchline media employee induction programme
, 2009 Includes bibliographical references (leaves 39-41).This is a theory evaluation of the Touchline Media (TLM) employee induction programme. Organisations use induction training as part of the new employee welcoming process, making it one of the most common
Hendricks, Kenrick
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Фізика і хімія твердого тіла, 2018 The proposed work shows analytical way to find a build-up time (induction period) for a mode of steady flameless catalytic combustion on metallic wire for cool air-gas mixtures with combustible gaseous admixtures using as an example flameless combustion ...
V. V. Kalinchak +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Induction period observation in the conversion of C1-derivatives to light olefins
, 2010 The initial transformations of methanol or chloromethane over SAPO-34 and ZSM-5 catalyst were investigated by a consecutive pulse reaction system. The induction period, in which an organic-free catalyst could be transferred to a working catalyst, was ...
Bao +4 more
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source