Results 91 to 100 of about 1,722,169 (314)

Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

open access: yesMolecular Oncology, EarlyView.
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa   +13 more
wiley   +1 more source

Applied Sciences Approaches in Higher Education Institution in Kosovo

open access: yesEIRP Proceedings, 2020
In a fast-changing global economy where the path to employability and competitiveness is determined by the ability to apply know-how knowledges and skills, a closer cooperation between education providers and businesses is inevitable in order to have ...
Meha Arbresha
doaj  

KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells

open access: yesMolecular Oncology, EarlyView.
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock   +10 more
wiley   +1 more source

Polyfunctional CD8+CD226+RUNX2hi effector T cells are diminished in advanced stages of chronic lymphocytic leukemia

open access: yesMolecular Oncology, EarlyView.
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar   +4 more
wiley   +1 more source

Adolf Jebavý – uzenářský mistr a mecenáš kulturního života K historii a pramenům jednoho z nejvýznamnějších brněnských výrobců [PDF]

open access: yesMuzeológia a Kultúrne Dedičstvo, 2019
This paper focuses on the history and production of the Adolf Jebavý factory – one of the famous family meat industry companies in Brno in the first half of the 20th Century.
Marie Gilbertová
doaj  

Industrial ecology of the paper industry

open access: yesWater Science and Technology, 1999
Industrial ecology (IE) is a biological concept applied to industrial structures. The basic concepts of IE include regional, intra-firm and product-based waste recycling systems as well as the principle of upward and downward cascading. In best current examples of regional systems, several parties are in an industrial waste re-use symbiosis.
openaire   +2 more sources

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

open access: yesMolecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy   +12 more
wiley   +1 more source

The history of plastics: from the Capitol to the Tarpeian Rock

open access: yesField Actions Science Reports, 2019
Few industries like plastic have experienced similar growth in the space of 60 years, both in terms of production tonnage and use in virtually every moment of our daily lives. However, plastic is now victim of its own success.
Philippe Chalmin
doaj  

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