Results 41 to 50 of about 141,590 (258)
Brazilian experts' consensus on the treatment of infantile epileptic spasm syndrome in infants
Arquivos de Neuro-Psiquiatria, 2023 Background Infantile epileptic spasms syndrome (IESS) is a rare but severe condition affecting children early and is usually secondary to an identifiable brain disorder.
Letícia Pereira de Brito Sampaio +7 more
doaj +1 more source
The mystery of the Doctor's son, or the riddle of West syndrome. [PDF]
, 2002 Although the eponym "West syndrome" is used widely for infantile spasms, the originators of the term and the time frame of its initial use are not well known. This article provides historical details about Dr. West, about his son who had infantile spasms,
Baram, Tallie Z +3 more
core +5 more sources
Epilepsia Open, 2021 Etiological classification of infantile spasms syndrome (ISS) is important, considering the influence on prognosis based on the presence or absence of a known etiology.
J. Wanigasinghe +9 more
semanticscholar +1 more source
Treatment of infantile spasms: emerging insights from clinical and basic science perspectives. [PDF]
, 2011 Infantile spasms is an epileptic encephalopathy of early infancy with specific clinical and electroencephalographic (EEG) features, limited treatment options, and a poor prognosis.
Arnason, Barry GW +10 more
core +2 more sources
Pediatric Clinics of North America, 1989 Infantile spasms are a unique disorder of infancy and early childhood. The average age at onset of infantile spasms is 6 months and the average incidence of the disorder is approximately 0.31 per 1000 live births. Approximately one-quarter of patients will spontaneously stop having spasms within 1 year of onset.
Richard A. Hrachovy, James D. Frost
openaire +5 more sources
Русский журнал детской неврологии, 2015 Epileptic spasms are epileptic seizures with sudden flexion/extension or of the mixed flexion and extension type, mainly involving the proximal and truncal muscles, that are normally longer than myoclonic seizures but shorter than tonic seizures, and ...
K. Yu. Mukhin, M. B. Mironov
doaj +1 more source
Frontiers in Neurology, 2021 Background: Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy is a rare autosomal recessive disorder caused by a mutation in the autoimmune regulator gene.
Go Kawano +9 more
doaj +1 more source
Cerebrospinal fluid corticotropin and cortisol are reduced in infantile spasms. [PDF]
, 1995 Infantile spasms respond to ACTH, and levels of the hormone in cerebrospinal fluid of untreated infants with this disorder were found to be lower than in age-matched controls. In this study we analyzed cerebrospinal fluid cortisol and ACTH using improved
Baram, TZ +4 more
core +2 more sources
Efficacy and tolerability of the Galanin Analog NAX 5055 in the multiple-hit rat model of symptomatic infantile spasms [PDF]
, 2013 Infantile spasms are seizures manifesting in infantile epileptic encephalopathies that are associated with poor epilepsy and cognitive outcomes. The current therapies are not always effective or are associated with serious side effects.
Galanopoulou, A.S. +4 more
core +1 more source
Antiepileptogenic effects of rapamycin in a model of infantile spasms due to structural lesions
Epilepsia, 2021 Infantile spasms may evolve into persistent epilepsies including Lennox‐Gastaut syndrome. We compared adult epilepsy outcomes in models of infantile spasms due to structural etiology (multiple‐hit model) or focal cortical inflammation and determined the ...
Ozlem Akman +4 more
semanticscholar +1 more source