Engineering a robust infectious clone and gene silencing vector from blackberry yellow vein associated virus [PDF]
Virus ResearchCriniviruses are emerging pathogens responsible for significant disease outbreaks worldwide. Among them, blackberry yellow vein-associated virus (BYVaV) is prevalent in blackberry-producing areas of the United States and, when present in the blackberry ...
Andrea Sierra-Mejia +4 more
doaj +3 more sources
Short ‘1.2× Genome’ Infectious Clone Initiates Kolmiovirid Replication in Boa constrictor Cells [PDF]
Viruses, 2022 Human hepatitis D virus (HDV) depends on hepatitis B virus co-infection and its glycoproteins for infectious particle formation. HDV was the sole known deltavirus for decades and believed to be a human-only pathogen.
Leonora Szirovicza +3 more
doaj +2 more sources
Construction of chicken infectious anemia virus infectious clone and study on its pathogenicity [PDF]
Frontiers in Microbiology, 2022 Chicken infectious anemia virus (CIAV) can be transmitted through contaminated live poultry vaccine. However, the pathogenicity of contaminated CIAV strains is rarely reported.
Jinjin Wang +7 more
doaj +2 more sources
The development and characterization of a stable Coxsackievirus A16 infectious clone with Nanoluc reporter gene [PDF]
Frontiers in Microbiology, 2023 Coxsackievirus A16 (CA16) belongs to the Human Enterovirus A species, which is a common pathogen causing hand, foot, and mouth disease in children. Currently, specific vaccines and drugs against CA16 are unavailable, and there is an unmet need to further
Rui Yu +9 more
doaj +2 more sources
Construction and Rescue of a DNA-Launched DENV2 Infectious Clone [PDF]
Viruses, 2023 Flaviviruses represent a large group of globally significant, insect-borne pathogens. For many of these viruses, there is a lack of antivirals and vaccines.
Madeline Holliday +2 more
doaj +2 more sources
Construction of a Full-Length Infectious Clone Derived from Type O Foot-and-Mouth Disease Virus Isolated in South Korea for Vaccine Development with High Antigen Productivity [PDF]
VaccinesBackground: Foot-and-mouth disease (FMD) is a highly contagious viral disease of cloven-hoofed animals such as cattle and pigs, characterized by vesicular lesions in the mouth, nose, teats, and feet.
Jae Young Kim +6 more
doaj +2 more sources
Rapid Construction of an Infectious Clone of the Zika Virus, Strain ZKC2 [PDF]
Frontiers in Microbiology, 2021 Zika virus (ZIKV) has had detrimental effects on global public health in recent years. This is because the management of the disease has been limited, in part because its pathogenic mechanisms are not yet completely understood.
Zhiran Qin +9 more
doaj +2 more sources
Characterization of a Virus Rescued from a Full-Length Infectious Clone Derived from the Type A Foot-and-Mouth Disease Virus Isolated in South Korea [PDF]
VirusesFoot-and-mouth disease (FMD), a vesicular disease, causes lesions in the mouth, nose, teats, and feet of cloven-hoofed animals. Vaccination remains the most effective method to prevent FMD outbreaks.
Jae Young Kim +6 more
doaj +2 more sources
Construction and Characterization of a Botrytis Virus F Infectious Clone [PDF]
Journal of Fungi, 2022 Botrytis virus F (BVF) is a positive-sense, single-stranded RNA (+ssRNA) virus within the Gammaflexiviridae family of the plant-pathogenic fungus Botrytis cinerea. In this study, the complete sequence of a BVF strain isolated from B.
Laura Córdoba +3 more
doaj +2 more sources
Epitope Addition and Ablation via Manipulation of a Dengue Virus Serotype 1 Infectious Clone
mSphere, 2017 Despite the clinical relevance, dengue virus (DENV) research has been hampered by the absence of robust reverse genetic systems to manipulate the viral serotypes for propagation and generation of mutant viruses.
Emily N. Gallichotte +7 more
doaj +3 more sources