Results 71 to 80 of about 685,992 (231)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

Development of an infectious clone system to study the life cycle of Hazara virus [PDF]

open access: yes, 2020
Crimean-Congo hemorrhagic fever orthonairovirus (CCHFV) is a negative sense single stranded RNA virus, capable of causing fatal hemorrhagic fever in humans.
Fuller, Jack
core   +4 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Using Compilation/Decompilation to Enhance Clone Detection [PDF]

open access: yes, 2017
We study effects of compilation and decompilation to code clone detection in Java. Compilation/decompilation canonicalise syntactic changes made to source code and can be used as source code normalisation.
Chaiyong Ragkhitwetsagul   +3 more
core   +1 more source

Construction of GarV-C infectious clone.

open access: yes, 2023
(A) Diagram of the GarV-C infectious clone containing either BCRP or DCRP. The binary vector pBI101 containing the 35S:GarV-C construct (pBI-GarV-C) was created, then the CRP of GarV-C was exchanged with either BCRP or DCRP. (B) Inoculation method of the
Shusuke Kawakubo (11807321)   +3 more
core   +1 more source

Genome-Wide Association Study of Soybean Mosaic Virus Resistance with a GFP-Based Rapid Evaluation System

open access: yesAgronomy
Soybean mosaic virus (SMV) is a major viral pathogen that causes significant yield losses and a reduction in seed quality in susceptible soybean cultivars. Resistance breeding is the most effective, economical, and eco-friendly strategy for prevention of
Jiaying Zhou   +9 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Human monkeypox preparedness in Latin America – Are we ready for the next viral zoonotic disease outbreak after COVID-19?

open access: yes, 2022
Instituto de Infectologia Emílio RibasBrazilian Society for Infectious DiseasesLatin American Network of Coronavirus Disease 2019-COVID-19 Research (LANCOVID-19)Universidade Federal do Rio de JaneiroUniversidade Federal do ParanáUniversidade Estadual ...
Cimerman, Sergio   +4 more
core   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

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