Results 141 to 150 of about 1,253,356 (303)
ABSTRACT Background Sphingosine‐1‐phosphate receptor modulators (S1PRM) are used to treat relapsing multiple sclerosis (MS). Each drug has a different S1PR‐subtype selectivity. They target the G‐protein coupled S1P receptors and exert significant immunomodulatory effects, such as preventing the formation of new CNS lesions and the reactivation of pre ...
Faizan Shahzad+8 more
wiley +1 more source
Preparedness and Response Considerations for High-Consequence Infectious Disease. [PDF]
Chan J+7 more
europepmc +1 more source
Epidemiology and Laboratory Diagnosis of Infectious Jaundice (Weil's Disease)
Joseph G. Molner, Joseph A. Kasper
openalex +2 more sources
In Vitro Modeling of Natural Killer Cell Cytotoxicity to Inform Personalized ALS Therapeutics
ABSTRACT Objective Natural killer (NK) cells might contribute to motor neuron death in amyotrophic lateral sclerosis (ALS) through direct cytotoxicity, a process that could be inhibited with the FDA‐approved JAK/STAT pathway inhibitor, tofacitinib. This study aimed to verify that tofacitinib can suppress NK cell cytotoxicity, investigate if immune cell
Benjamin J. Murdock+8 more
wiley +1 more source
Surveillance System for Infectious Disease Prevention and Management: Direction of Korea's Infectious Disease Surveillance System. [PDF]
Jang Y, Lee H, Park H.
europepmc +1 more source
Nanomedicine for Infectious Diseases [PDF]
Harald Unterweger+6 more
openaire +3 more sources
Association of the ICH Score With Withdrawal of Life‐Sustaining Treatment Over a 10‐Year Period
ABSTRACT Objective The intracerebral hemorrhage (ICH) score was developed to enhance provider communication and facilitate early severity assessment. We examined the association of the ICH score with mortality and withdrawal of life‐sustaining treatment (WLST) in a large, multicenter stroke registry, and evaluated temporal trends in these associations.
Nina Massad+15 more
wiley +1 more source
ABSTRACT Objective We aimed to investigate the comparative effectiveness of standard versus personalized extended interval dosing of anti‐CD20 therapy on clinical and sub‐clinical outcomes in multiple sclerosis. Methods Clinical information was collected prospectively on Research Electronic Data Capture.
Nabil K. El Ayoubi+6 more
wiley +1 more source
Synthetic method of analogues for emerging infectious disease forecasting. [PDF]
Murph AC+6 more
europepmc +1 more source