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2022
1 ABSTRACT Infectious Spleen and Kidney Necrosis Virus (ISKNV) is increasingly gaining more attention globally, due to its highly significant economic impact on the aquaculture industry. In late 2018, unusually high levels of mortality (60-90%) was reported in some intensive tilapia cage culture systems in Ghana ...
Angela Naa Amerley Ayiku +10 more
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1 ABSTRACT Infectious Spleen and Kidney Necrosis Virus (ISKNV) is increasingly gaining more attention globally, due to its highly significant economic impact on the aquaculture industry. In late 2018, unusually high levels of mortality (60-90%) was reported in some intensive tilapia cage culture systems in Ghana ...
Angela Naa Amerley Ayiku +10 more
openaire +1 more source
Aquaculture, 2019
Abstract The genus Megalocytivirus (MCV) includes Infectious spleen and kidney necrosis virus (ISKNV) and red seabream iridovirus (RSIV) which are listed by the World Organization for Animal Health (OIE). MCV has a broad host range and can be present as a persistent subclinical infection in some fish.
Cahya Fusianto +2 more
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Abstract The genus Megalocytivirus (MCV) includes Infectious spleen and kidney necrosis virus (ISKNV) and red seabream iridovirus (RSIV) which are listed by the World Organization for Animal Health (OIE). MCV has a broad host range and can be present as a persistent subclinical infection in some fish.
Cahya Fusianto +2 more
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A rapid lateral flow immunoassay for infectious spleen and kidney necrosis virus (ISKNV)
TalantaA rapid, instrument-free lateral flow immunoassay (LFIA) device was developed and validated for screening of the ISKNV antigen. Based on a sandwich immunoassay format, two monoclonal antibodies targeting distinct viral epitopes were employed for capture and detection.
Kwanchanok, Wajasen +5 more
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Journal of Fish Diseases, 2022
AbstractThe infectious spleen and kidney necrosis virus (ISKNV) is a highly lethal virus, which has brought significant losses to aquaculture. Therefore, a new vaccine against ISKNV with high efficiency, safety and convenience must be developed. While baculoviruses are more commonly used as protein expression systems for vaccine antigen production ...
Min Zhu +11 more
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AbstractThe infectious spleen and kidney necrosis virus (ISKNV) is a highly lethal virus, which has brought significant losses to aquaculture. Therefore, a new vaccine against ISKNV with high efficiency, safety and convenience must be developed. While baculoviruses are more commonly used as protein expression systems for vaccine antigen production ...
Min Zhu +11 more
openaire +2 more sources
Fish & Shellfish Immunology, 2019
Mandarin fish (Siniperca chuatsi) is a significant cultured species with high added value in China. With the expansion of farming, diseases of mandarin fish such as Infectious spleen and kidney necrosis virus (ISKNV) diseases are becoming more and more serious.
Yi-Fan Lin +8 more
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Mandarin fish (Siniperca chuatsi) is a significant cultured species with high added value in China. With the expansion of farming, diseases of mandarin fish such as Infectious spleen and kidney necrosis virus (ISKNV) diseases are becoming more and more serious.
Yi-Fan Lin +8 more
openaire +2 more sources
Aquaculture, 2002
The pathogenicity of infectious spleen and kidney necrosis virus (ISKNV) was examined by infection trials in the first known host species, the mandarinfish, Siniperca chuatsi, and in 20 other teleosts cultured in China. Mandarinfish and large-mouth bass, Micropterus salmoides, were highly susceptible to infection after intraperitoneal infection of ...
J.G He, K Zeng, S.P Weng, S.-M Chan
exaly +2 more sources
The pathogenicity of infectious spleen and kidney necrosis virus (ISKNV) was examined by infection trials in the first known host species, the mandarinfish, Siniperca chuatsi, and in 20 other teleosts cultured in China. Mandarinfish and large-mouth bass, Micropterus salmoides, were highly susceptible to infection after intraperitoneal infection of ...
J.G He, K Zeng, S.P Weng, S.-M Chan
exaly +2 more sources
VP15R from infectious spleen and kidney necrosis virus is a non-muscle myosin-II-binding protein
Archives of Virology, 2010VP15R protein, encoded by the 15th open reading frame of infectious spleen and kidney necrosis virus (ISKNV), was identified. VP15R is a 263-residue protein that is first transcribed within 12 h post-infection. The VP15R mRNA is transcribed beginning at ISKNV genomic coordinate 12111, extending 167 bp upstream of the initiation codon.
Xiaopeng, Xu +8 more
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Virus Genes, 2014
Infectious spleen and kidney necrosis virus (ISKNV) belongs to the genus Megalocytivirus in the family Iridoviridae. This virus is the etiological agent of a serious and pandemic disease in fish. Cells infected with ISKNV undergo apoptosis. In this study, the ISKNV ORF005L gene was characterized and functionally investigated.
Rui, Wang +6 more
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Infectious spleen and kidney necrosis virus (ISKNV) belongs to the genus Megalocytivirus in the family Iridoviridae. This virus is the etiological agent of a serious and pandemic disease in fish. Cells infected with ISKNV undergo apoptosis. In this study, the ISKNV ORF005L gene was characterized and functionally investigated.
Rui, Wang +6 more
openaire +2 more sources
Virus Research, 2007
Infectious spleen and kidney necrosis virus (ISKNV) is the etiological agent that causes a pandemic and severe disease in fish characteristic of enlarged and damaged spleen and kidney. To identify viral proteins involved in infection and pathogenesis, we characterized five open reading frames (ORFs) of the ISKNV genome, ORF12, ORF65, ORF66, ORF99 and ...
Junfeng, Xie +8 more
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Infectious spleen and kidney necrosis virus (ISKNV) is the etiological agent that causes a pandemic and severe disease in fish characteristic of enlarged and damaged spleen and kidney. To identify viral proteins involved in infection and pathogenesis, we characterized five open reading frames (ORFs) of the ISKNV genome, ORF12, ORF65, ORF66, ORF99 and ...
Junfeng, Xie +8 more
openaire +2 more sources
Fish & Shellfish Immunology, 2020
The mandarin fish Siniperca chuatsi is a cultured freshwater fish species that is popular in China because of its high market value. With the development of high-density cultural mode in mandarin fish, viral diseases such as Infectious spleen and kidney necrosis virus (ISKNV) are becoming increasingly serious.
Xiao-Wei, Qin +8 more
openaire +2 more sources
The mandarin fish Siniperca chuatsi is a cultured freshwater fish species that is popular in China because of its high market value. With the development of high-density cultural mode in mandarin fish, viral diseases such as Infectious spleen and kidney necrosis virus (ISKNV) are becoming increasingly serious.
Xiao-Wei, Qin +8 more
openaire +2 more sources