Results 201 to 210 of about 32,133 (227)
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Journal of General Virology, 2023
Infectious spleen and kidney necrosis virus disease (ISKNVD) caused significant economic losses to the fishery industry. Epidermal growth factor receptor (EGFR), phosphatidylinositide 3-kinase (PI3K) played an important role in ISKNV invasion. However, the molecular regulatory mechanisms among EGFR, PI3K-Akt, and ISKNV invasion are not clear.
Yinjie, Niu +7 more
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Infectious spleen and kidney necrosis virus disease (ISKNVD) caused significant economic losses to the fishery industry. Epidermal growth factor receptor (EGFR), phosphatidylinositide 3-kinase (PI3K) played an important role in ISKNV invasion. However, the molecular regulatory mechanisms among EGFR, PI3K-Akt, and ISKNV invasion are not clear.
Yinjie, Niu +7 more
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Journal of Fish Diseases, 2022
AbstractThe infectious spleen and kidney necrosis virus (ISKNV) is a highly lethal virus, which has brought significant losses to aquaculture. Therefore, a new vaccine against ISKNV with high efficiency, safety and convenience must be developed. While baculoviruses are more commonly used as protein expression systems for vaccine antigen production ...
Min Zhu +11 more
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AbstractThe infectious spleen and kidney necrosis virus (ISKNV) is a highly lethal virus, which has brought significant losses to aquaculture. Therefore, a new vaccine against ISKNV with high efficiency, safety and convenience must be developed. While baculoviruses are more commonly used as protein expression systems for vaccine antigen production ...
Min Zhu +11 more
openaire +2 more sources
Transboundary and Emerging Diseases, 2020
Infectious spleen and kidney necrosis virus (ISKNV), a member of family iridoviridae, reported for the first time in a wide range of ornamental fish species in India. Significant mortalities during the year 2018-19 were reported from a number of retailers in the region with various clinical signs.
S. K. Girisha +9 more
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Infectious spleen and kidney necrosis virus (ISKNV), a member of family iridoviridae, reported for the first time in a wide range of ornamental fish species in India. Significant mortalities during the year 2018-19 were reported from a number of retailers in the region with various clinical signs.
S. K. Girisha +9 more
openaire +2 more sources
Fish & Shellfish Immunology, 2022
The PI3K/AKT/p53 signaling pathway is activated by various types of cellular stimuli or pathogenic infection, and then regulates fundamental cellular functions to combat these stimulations. Here, we studied the meaningful roles of PI3K/AKT/p53 in regulating cellular machine such as autophagy, immune responses, as well as antiviral activity in Chinese ...
Xiaoting Zhang +8 more
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The PI3K/AKT/p53 signaling pathway is activated by various types of cellular stimuli or pathogenic infection, and then regulates fundamental cellular functions to combat these stimulations. Here, we studied the meaningful roles of PI3K/AKT/p53 in regulating cellular machine such as autophagy, immune responses, as well as antiviral activity in Chinese ...
Xiaoting Zhang +8 more
openaire +2 more sources
Aquaculture, 2019
Abstract The genus Megalocytivirus (MCV) includes Infectious spleen and kidney necrosis virus (ISKNV) and red seabream iridovirus (RSIV) which are listed by the World Organization for Animal Health (OIE). MCV has a broad host range and can be present as a persistent subclinical infection in some fish.
Cahya Fusianto +2 more
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Abstract The genus Megalocytivirus (MCV) includes Infectious spleen and kidney necrosis virus (ISKNV) and red seabream iridovirus (RSIV) which are listed by the World Organization for Animal Health (OIE). MCV has a broad host range and can be present as a persistent subclinical infection in some fish.
Cahya Fusianto +2 more
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VP15R from infectious spleen and kidney necrosis virus is a non-muscle myosin-II-binding protein
Archives of Virology, 2010VP15R protein, encoded by the 15th open reading frame of infectious spleen and kidney necrosis virus (ISKNV), was identified. VP15R is a 263-residue protein that is first transcribed within 12 h post-infection. The VP15R mRNA is transcribed beginning at ISKNV genomic coordinate 12111, extending 167 bp upstream of the initiation codon.
Xiaopeng, Xu +8 more
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JOURNAL OF SUSTAINABILITY SCIENCE AND MANAGEMENT, 2022
The Malaysian ornamental fish industry’s recent production is recorded at RM350 million per annum. An Infectious Spleen and Kidney Necrosis Virus (ISKNV), one of the Megalocytivirus strains has been related to significant systemic infections that has ravaged ornamental fish stocks and had a severe financial impact on businesses in the sector.
SANDRA CATHERINE ZAINATHAN +6 more
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The Malaysian ornamental fish industry’s recent production is recorded at RM350 million per annum. An Infectious Spleen and Kidney Necrosis Virus (ISKNV), one of the Megalocytivirus strains has been related to significant systemic infections that has ravaged ornamental fish stocks and had a severe financial impact on businesses in the sector.
SANDRA CATHERINE ZAINATHAN +6 more
openaire +1 more source
Virus Research, 2007
Infectious spleen and kidney necrosis virus (ISKNV) is the etiological agent that causes a pandemic and severe disease in fish characteristic of enlarged and damaged spleen and kidney. To identify viral proteins involved in infection and pathogenesis, we characterized five open reading frames (ORFs) of the ISKNV genome, ORF12, ORF65, ORF66, ORF99 and ...
Junfeng, Xie +8 more
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Infectious spleen and kidney necrosis virus (ISKNV) is the etiological agent that causes a pandemic and severe disease in fish characteristic of enlarged and damaged spleen and kidney. To identify viral proteins involved in infection and pathogenesis, we characterized five open reading frames (ORFs) of the ISKNV genome, ORF12, ORF65, ORF66, ORF99 and ...
Junfeng, Xie +8 more
openaire +2 more sources
Archives of Virology, 2006
Infectious spleen and kidney necrosis virus-like (ISKNV-like) virus causes a serious systemic disease with high morbidity and mortality of freshwater and marine fishes. Based on the ISKNV putative major capsid protein (MCP), the vascular endothelial growth factor (VEGF), the mRNA capping enzyme (Capping), and the tumor necrosis factor receptor ...
Y Q, Wang +5 more
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Infectious spleen and kidney necrosis virus-like (ISKNV-like) virus causes a serious systemic disease with high morbidity and mortality of freshwater and marine fishes. Based on the ISKNV putative major capsid protein (MCP), the vascular endothelial growth factor (VEGF), the mRNA capping enzyme (Capping), and the tumor necrosis factor receptor ...
Y Q, Wang +5 more
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Fish & Shellfish Immunology, 2019
Mandarin fish (Siniperca chuatsi) is a significant cultured species with high added value in China. With the expansion of farming, diseases of mandarin fish such as Infectious spleen and kidney necrosis virus (ISKNV) diseases are becoming more and more serious.
Yi-Fan Lin +8 more
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Mandarin fish (Siniperca chuatsi) is a significant cultured species with high added value in China. With the expansion of farming, diseases of mandarin fish such as Infectious spleen and kidney necrosis virus (ISKNV) diseases are becoming more and more serious.
Yi-Fan Lin +8 more
openaire +2 more sources