Results 191 to 200 of about 32,133 (227)

Identification of infectious spleen and kidney necrosis virus (ISKNV)-encoded microRNAs

Virus Genes, 2020
MicroRNAs (miRNAs) are small noncoding RNAs that post-transcriptionally regulate gene expression by complementary binding to target mRNAs. Virus-encoded miRNAs play important roles in virus life cycle and virus-host interactions. Viruses from the Megalocytivirus genus, family Iridoviridae, infect a wide range of fishes, bringing great challenges to ...
Jian-hui He, Qiong Xia, Shaoping Weng, Jianguo He, Xiaopeng Xu   +4 more
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Identification of the VP92R gene from infectious spleen and kidney necrosis virus

Virus Genes, 2010
Megalocytiviruses, which belong to the family Iridoviridae, are among the most harmful viruses to cultured fishes. Infectious spleen and kidney necrosis virus (ISKNV) is the type species of the Megalocytivirus genus. The genome of ISKNV was sequenced and annotated by He et al. (Virology 291:126-139, 2001) in 2001 and re-annotated by Eaton et al. (Virol.
Xiaopeng, Xu, Qingxia, Lu, Rui, Wang, Ting, Lin, Shaoping, Weng, Ling, Lu, Zhongsheng, Li, Xiaoqiang, Yu, Junliang, Tang, Jianguo, He   +9 more
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Genotype and host range analysis of infectious spleen and kidney necrosis virus (ISKNV)

Virus Genes, 2010
Infectious spleen and kidney necrosis virus (ISKNV) is the causative agent of a disease causing high mortality in mandarin fish, Siniperca chuatsi. In this study, complete major capsid protein (MCP) genes of nine ISKNV isolates were sequenced and compared with other known megalocytiviruses to evaluate genetic variation and host range of the viruses ...
Xiaozhe, Fu, Ningqiu, Li, Lihui, Liu, Qiang, Lin, Fang, Wang, Yingtiao, Lai, Haiming, Jiang, Houjun, Pan, Cunbin, Shi, Shuqin, Wu   +9 more
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Transcriptional programs of infectious spleen and kidney necrosis virus (ISKNV) in vitro and in vivo

Virus Genes, 2020
Infectious spleen and kidney necrosis virus (ISKNV), causing serious infectious diseases to marine and freshwater fishes, is the type species of the genus Megalocytivirus, family Iridoviridae. In this study, the transcriptional programs of ISKNV in vitro (MFF-1 cells) and in vivo (spleens from mandarin fish) were investigated using real-time PCR ...
Jian-hui He, Lichao Huang, Zhixun Guo, Shaoping Weng, Jianguo He, Xiaopeng Xu   +5 more
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Antigenic identification of virion structural proteins from infectious spleen and kidney necrosis virus

Fish & Shellfish Immunology, 2011
Infectious spleen and kidney necrosis virus (ISKNV), belonging to the genus Megalocytivirus in the family Iridoviridae, is one of the major agents causing mortality and economic losses to the freshwater fish culture industry in Asian countries. Currently, little information regarding the antigenic properties of Megalocytivirus (especially ISKNV) is ...
Xiao-Peng, Xiong, Chuan-Fu, Dong, Shao-Ping, Weng, Jing, Zhang, Ye, Zhang, Jian-Guo, He   +5 more
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Autophagy promoted infectious kidney and spleen necrosis virus replication and decreased infectious virus yields in CPB cell line

Fish & Shellfish Immunology, 2017
Autophagy plays important functions in viral replication and pathogenesis. In this study, we investigated the role of autophagy in the replication of infectious kidney and spleen necrosis virus (ISKNV), an agent that has caused devastating losses in Chinese perch (Siniperca chuatsi) industry.
Chen, Li, Xiaozhe, Fu, Qiang, Lin, Lihui, Liu, Hongru, Liang, Zhibin, Huang, Ningqiu, Li   +6 more
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Gefitinib inhibits infectious spleen and kidney necrosis virus infection in vivo and vitro by blocking virus endocytosis

Aquaculture, 2021
Abstract Infectious spleen and kidney necrosis virus disease (ISKNVD) caused significant economic losses to the fishery industry. So it is urgent to develop an effective measure for prevention ISKNVD. In this study, we investigated the effects of gefitinib against ISKNV in vitro and vivo.
Yinjie Niu, Xiaozhe Fu, Qiang Lin, Lihui Liu, Xia Luo, Hongru Liang, Ningqiu Li   +6 more
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Characterization of a membrane protein (VP001L) from infectious spleen and kidney necrosis virus (ISKNV)

Virus Genes, 2007
Infectious spleen and kidney necrosis virus (ISKNV) is the type species of megalocytivirus, Iridoviridae. A novel membrane protein corresponding to the first open reading frame (ORF001L) of ISKNV genome was identified. This 378-residue protein, termed the VP001L protein, has a high content of hydrophobic sequences and contains 10-11 putative ...
Xiaopeng, Xu, Jing, Lu, Qingxia, Lu, Hui, Zhong, Shaoping, Weng, Jianguo, He   +5 more
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Molecular epidemiology of Infectious Spleen and Kidney Necrosis Virus (ISKNV) in Ghanaian cultured tilapia

2022
1ABSTRACTInfectious Spleen and Kidney Necrosis Virus (ISKNV) is increasingly gaining more attention globally, due to its highly significant economic impact on the aquaculture industry. In late 2018, unusually high levels of mortality (60-90%) was reported in some intensive tilapia cage culture systems in Ghana.
Angela Naa Amerley Ayiku, Abigail Akosua Adelani, Patrick Appenteng, Mary Nkansah, Joyce M. Ngoi, Collins Misita Morang’a, Richard Paley, Kofitsyo S. Cudjoe, David Verner-Jeffreys, Peter Kojo Quashie, Samuel Duodu   +10 more
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Deleting ORF71L of infectious spleen and kidney necrosis virus (ISKNV) resulted in virulence attenuation in Mandarin fish

Fish & Shellfish Immunology, 2022
Infectious spleen and kidney necrosis virus (ISKNV), the type species of the genus Megalocytivirus, infects a variety of teleost fish species and causes substantial losses in the aquaculture industry worldwide. ISKNV ORF71L is 1611 bp in length, encodes a 537-amino-acid peptide and was previously identified as a viral structural protein in the ISKNV ...
Hetong Zhang, Hemei Qi, Shaoping Weng, Jianguo He, Chuanfu Dong   +4 more
openaire   +2 more sources