Experimental Infection and the Effects of Temperature on the Pathogenicity of the Infectious Spleen and Kidney Necrosis Virus in Juvenile Nile Tilapia (Oreochromis niloticus) [PDF]
The infectious spleen and kidney necrosis virus (ISKNV) is one of the most important emerging viral pathogens for Nile tilapia (Oreochromis niloticus) farming. While prevalent worldwide, it has recently been detected in Brazil.
Tarcísio Martins França e Silva +2 more
doaj +4 more sources
Global landscape of structural proteins of infectious spleen and kidney necrosis virus. [PDF]
ABSTRACT Infectious spleen and kidney necrosis virus (ISKNV), the type species of the genus Megalocytivirus in the family Iridoviridae , causes severe damage to mandarin fish cultures in China. Little is known about the proteins of ISKNV virions.
Dong CF +7 more
europepmc +6 more sources
Evaluation of a Low-Temperature Immersion Immunization Strategy for the Infectious Spleen and Kidney Necrosis Virus orf037l Gene-Deleted Attenuated Vaccine [PDF]
Background: Infectious spleen and kidney necrosis virus (ISKNV) poses a significant threat to aquaculture sustainability, particularly affecting mandarin fish (Siniperca chuatsi) and causing significant economic losses. Methods: To address this challenge,
Weiqiang Pan +9 more
doaj +4 more sources
Infectious Spleen and Kidney Necrosis Virus (ISKNV) Triggers Mitochondria-Mediated Dynamic Interaction Signals via an Imbalance of Bax/Bak over Bcl-2/Bcl-xL in Fish Cells [PDF]
The molecular pathogenesis of infectious spleen and kidney necrosis virus (ISKNV) infections is important but has rarely been studied in connection to host organelle behavior.
Pin-Han Chen +3 more
doaj +4 more sources
Accelerated Metabolite Levels of Aerobic Glycolysis and the Pentose Phosphate Pathway Are Required for Efficient Replication of Infectious Spleen and Kidney Necrosis Virus in Chinese Perch Brain Cells [PDF]
Glucose is a main carbon and energy source for virus proliferation and is usually involved in the glycolysis, pentose phosphate pathway (PPP), and tricarboxylic acid cycle (TCA cycle) pathways.
Xixi Guo +8 more
doaj +4 more sources
In field use of water samples for genomic surveillance of infectious spleen and kidney necrosis virus (ISKNV) infecting tilapia fish in Lake Volta, Ghana [PDF]
Viral outbreaks are a constant threat to aquaculture, limiting production for better global food security. A lack of diagnostic testing and monitoring in resource-limited areas hinders the capacity to respond rapidly to disease outbreaks and to prevent ...
Shayma Alathari +10 more
doaj +5 more sources
A zebrafish (Danio rerio) model of infectious spleen and kidney necrosis virus (ISKNV) infection [PDF]
Zebrafish is a model animal for studies of genetics, development, toxicology, oncology, and immunology. In this study, infectious spleen and kidney necrosis virus (ISKNV) was used to establish an infection in zebrafish, and the experimental conditions were established and characterized.
Xu, Xiaopeng +9 more
openaire +3 more sources
Partial validation of a TaqMan quantitative polymerase chain reaction for the detection of the three genotypes of Infectious spleen and kidney necrosis virus. [PDF]
Megalocytiviruses (MCVs) are double-stranded DNA viruses known to infect important freshwater and marine fish species in the aquaculture, food, and ornamental fish industries worldwide.
Samantha A Koda +5 more
doaj +3 more sources
Tetraodon nigroviridis as a nonlethal model of infectious spleen and kidney necrosis virus (ISKNV) infection [PDF]
Infectious spleen and kidney necrosis virus (ISKNV) is the type species of the genus Megalocytivirus, family Iridoviridae. We have previously established a high mortality ISKNV infection model of zebrafish (Danio rerio). In this study, a nonlethal Tetraodon nigroviridis model of ISKNV infection was established.
Xu, Xiaopeng +10 more
openaire +3 more sources
Risk of Spread of Megalocytivirus pagrus1 (Infectious Spleen and Kidney Necrosis Virus) From Frozen Fillets. [PDF]
ABSTRACT Infectious spleen and kidney necrosis virus (ISKNV) is a significant threat to global aquatic food security by causing large‐scale mortality in the aquaculture of tilapia ( Oreochromis niloticus ) and mandarin fish (
Becker JA +6 more
europepmc +3 more sources

