Results 11 to 20 of about 32,133 (227)

First detection of infectious spleen and kidney necrosis virus (ISKNV) associated with massive mortalities in farmed tilapia in Africa. [PDF]

Transbound Emerg Dis, 2021
SummaryIn late 2018, unusual patterns of very high mortality (>50% production) were reported in intensive tilapia cage culture systems across Lake Volta in Ghana. Samples of fish and fry were collected and analysed from two affected farms between October 2018 and February 2019.
Ramírez-Paredes JG, Paley RK, Hunt W, Feist SW, Stone DM, Field TR, Haydon DJ, Ziddah PA, Nkansa M, Guilder J, Gray J, Duodu S, Pecku EK, Awuni JA, Wallis TS, Verner-Jeffreys DW.   +15 more
europepmc   +6 more sources

Risk of Spread of Megalocytivirus pagrus1 (Infectious Spleen and Kidney Necrosis Virus) From Frozen Fillets. [PDF]

J Fish Dis
ABSTRACT Infectious spleen and kidney necrosis virus (ISKNV) is a significant threat to global aquatic food security by causing large‐scale mortality in the aquaculture of tilapia ( Oreochromis niloticus ) and mandarin fish (
Becker JA, Hick PM, Megarani D, Siler H, Pierezan F, Gray SN, Subramaniam K.   +6 more
europepmc   +3 more sources

Experimental Infection and the Effects of Temperature on the Pathogenicity of the Infectious Spleen and Kidney Necrosis Virus in Juvenile Nile Tilapia (Oreochromis niloticus) [PDF]

Animals
The infectious spleen and kidney necrosis virus (ISKNV) is one of the most important emerging viral pathogens for Nile tilapia (Oreochromis niloticus) farming. While prevalent worldwide, it has recently been detected in Brazil.
Tarcísio Martins França e Silva, Guilherme Alves de Queiróz, Carlos Augusto Gomes Leal   +2 more
doaj   +2 more sources

Infectious Spleen and Kidney Necrosis Virus (ISKNV) Triggers Mitochondria-Mediated Dynamic Interaction Signals via an Imbalance of Bax/Bak over Bcl-2/Bcl-xL in Fish Cells [PDF]

Viruses, 2022
The molecular pathogenesis of infectious spleen and kidney necrosis virus (ISKNV) infections is important but has rarely been studied in connection to host organelle behavior.
Pin-Han Chen, Tsai-Ching Hsueh, Jen-Leih Wu, Jiann-Ruey Hong   +3 more
doaj   +2 more sources

High-throughput virtual screening of marine algae metabolites as high-affinity inhibitors of ISKNV major capsid protein: An analysis of in-silico models and DFT calculation to find novel drug molecules for fighting infectious spleen and kidney necrosis virus (ISKNV) [PDF]

Heliyon, 2023
Infectious Spleen and Kidney Necrosis Virus (ISKNV) is linked to severe infections that cause significant financial losses in global aquaculture. ISKNV enters the host cell through its major capsid protein (MCP), and the resulting infection can lead to ...
Sk Injamamul Islam, Sheikh Sunzid Ahmed, Nasim Habib, Md Akib Ferdous, Saloa Sanjida, Moslema Jahan Mou   +5 more
doaj   +2 more sources

Evaluation of a Low-Temperature Immersion Immunization Strategy for the Infectious Spleen and Kidney Necrosis Virus orf037l Gene-Deleted Attenuated Vaccine [PDF]

Vaccines
Background: Infectious spleen and kidney necrosis virus (ISKNV) poses a significant threat to aquaculture sustainability, particularly affecting mandarin fish (Siniperca chuatsi) and causing significant economic losses. Methods: To address this challenge,
Weiqiang Pan, Jiajie Fu, Ruoyun Zeng, Mingcong Liang, Yanlin You, Zhipeng Zhan, Zhoutao Lu, Shaoping Weng, Changjun Guo, Jianguo He   +9 more
doaj   +2 more sources

Mandarin fish tankyrase 1-like protein regulates the Wnt/β-catenin pathway and facilitates the infectious spleen and kidney necrosis virus replication [PDF]

Comparative Immunology Reports
Tankyrase (TNKS), a poly (ADP-ribose) polymerase (PARP) protein, mediates the PARylation of substrates, ultimately guiding them towards proteasome-dependent degradation or altering their localization.
Zhimin Li, Yashan Wu, Jian He, Kun Wu, Shaoping Weng, Changjun Guo, Jianguo He   +6 more
doaj   +2 more sources

Global landscape of structural proteins of infectious spleen and kidney necrosis virus. [PDF]

J Virol, 2011
ABSTRACT Infectious spleen and kidney necrosis virus (ISKNV), the type species of the genus Megalocytivirus in the family Iridoviridae , causes severe damage to mandarin fish cultures in China. Little is known about the proteins of ISKNV virions.
Dong CF, Xiong XP, Shuang F, Weng SP, Zhang J, Zhang Y, Luo YW, He JG.   +7 more
europepmc   +4 more sources

Rapid, sensitive, and visual detection of mandarin fish ranavirus and infectious spleen and kidney necrosis virus using an RPA-CRISPR/Cas12a system [PDF]

Frontiers in Microbiology
Iridoviruses are large cytoplasmic icosahedral viruses that contain dsDNA. Among them, mandarin fish ranavirus (MRV) and infectious spleen and kidney necrosis virus (ISKNV) are particularly notable due to their high contagiousness and pathogenicity ...
Zhoutao Lu, Mincong Liang, Chuanrui Li, Yichun Xu, Shaoping Weng, Jianguo He, Changjun Guo   +6 more
doaj   +2 more sources

VP08R from infectious spleen and kidney necrosis virus is a novel component of the virus-mock basement membrane. [PDF]

J Virol, 2014
ABSTRACT Infectious spleen and kidney necrosis virus (ISKNV), the type species of the genus Megalocytivirus , family Iridoviridae , brings great harm to fish farming. In infected tissues, ISKNV infection is characterized by a unique phenomenon, in that the infected cells are ...
Xu X, Yan M, Wang R, Lin T, Tang J, Li C, Weng S, He JG.   +7 more
europepmc   +4 more sources