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First report of infectious spleen and kidney necrosis virus (ISKNV) in two native cichlids cultured in Brazil [PDF]

open access: yesSemina: Ciências Agrárias
Peacock bass (syn.: tucunaré, Cichla ocellaris) and the pearl cichlids (syn.: acará, Geophagus brasiliensis) are South American cichlids that are highly valued in both the ornamental and sport fish industries.
Ulisses de Pádua Pereira   +9 more
doaj   +3 more sources

Detection and control of Infectious spleen and kidney necrosis virus in aquaculture [PDF]

open access: yes, 2021
Infectious spleen and kidney necrosis virus (ISKNV), genus Megalocytivirus, causes disease of fish, with infection reported for more than 52 marine and freshwater species (Subramaniam et al., 2014). The objective of this thesis was to generate knowledge to inform ISKNV disease control in aquaculture.
Fusianto, Cahya Kurnia
openaire   +4 more sources

High-throughput virtual screening of marine algae metabolites as high-affinity inhibitors of ISKNV major capsid protein: An analysis of in-silico models and DFT calculation to find novel drug molecules for fighting infectious spleen and kidney necrosis virus (ISKNV) [PDF]

open access: yesHeliyon, 2023
Infectious Spleen and Kidney Necrosis Virus (ISKNV) is linked to severe infections that cause significant financial losses in global aquaculture. ISKNV enters the host cell through its major capsid protein (MCP), and the resulting infection can lead to ...
Sk Injamamul Islam   +5 more
doaj   +2 more sources

Mandarin fish tankyrase 1-like protein regulates the Wnt/β-catenin pathway and facilitates the infectious spleen and kidney necrosis virus replication [PDF]

open access: yesComparative Immunology Reports
Tankyrase (TNKS), a poly (ADP-ribose) polymerase (PARP) protein, mediates the PARylation of substrates, ultimately guiding them towards proteasome-dependent degradation or altering their localization.
Zhimin Li   +6 more
doaj   +2 more sources

First outbreak of an infection with infectious spleen and kidney necrosis virus (ISKNV) in ornamental fish in Germany [PDF]

open access: yesDiseases of Aquatic Organisms, 2016
In 2014, infectious spleen and kidney necrosis virus (ISKNV), a member of the genus Megalocytivirus, was detected for the first time in ornamental fish in Germany. Since 2013, angelfish Pterophyllum spp. originating from Colombia have experienced significant epizootics in a number of German retailers' facilities.
Peter Wohlsein   +2 more
exaly   +3 more sources

VP08R from infectious spleen and kidney necrosis virus is a novel component of the virus-mock basement membrane. [PDF]

open access: yesJ Virol, 2014
ABSTRACT Infectious spleen and kidney necrosis virus (ISKNV), the type species of the genus Megalocytivirus , family Iridoviridae , brings great harm to fish farming. In infected tissues, ISKNV infection is characterized by a unique phenomenon, in that the infected cells are ...
Xu X   +7 more
europepmc   +4 more sources

Rapid, sensitive, and visual detection of mandarin fish ranavirus and infectious spleen and kidney necrosis virus using an RPA-CRISPR/Cas12a system [PDF]

open access: yesFrontiers in Microbiology
Iridoviruses are large cytoplasmic icosahedral viruses that contain dsDNA. Among them, mandarin fish ranavirus (MRV) and infectious spleen and kidney necrosis virus (ISKNV) are particularly notable due to their high contagiousness and pathogenicity ...
Zhoutao Lu   +6 more
doaj   +2 more sources

Early or Simultaneous Infection with Infectious Pancreatic Necrosis Virus Inhibits Infectious Hematopoietic Necrosis Virus Replication and Induces a Stronger Antiviral Response during Co-infection in Rainbow Trout (Oncorhynchus mykiss) [PDF]

open access: yesViruses, 2022
Infectious hematopoietic necrosis (IHN) and infectious pancreatic necrosis (IPN) are the most common viral diseases of salmon in aquaculture worldwide. The co-infection of rainbow trout (Oncorhynchus mykiss) with IHN virus (IHNV) and IPN virus (IPNV) is ...
Yizhi Shao   +5 more
doaj   +2 more sources

A novel viral SOCS from infectious spleen and kidney necrosis virus: interacts with Jak1 and inhibits IFN-α induced Stat1/3 activation. [PDF]

open access: yesPLoS ONE, 2012
Interferon (IFN)-induced Janus kinase (Jak)/signal transducer and activator of transcription (Stat) pathway is important in controlling immune responses and is negatively response-regulated by the suppressor of cytokine signaling (SOCS) proteins. However,
Chang-Jun Guo   +6 more
doaj   +3 more sources

Concurrent infection with piscine intestinal coccidia and infectious spleen and kidney necrosis virus associated with mass mortality and severe gastrointestinal pathology in juvenile Lates calcarifer [PDF]

open access: yesVeterinary World
Background and Aim: Concurrent infections in aquaculture species often exacerbate disease severity and complicate diagnosis and control strategies.
Watcharapol Suyapoh   +7 more
doaj   +2 more sources

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