Results 21 to 30 of about 16,276 (211)

Mandarin fish tankyrase 1-like protein regulates the Wnt/β-catenin pathway and facilitates the infectious spleen and kidney necrosis virus replication [PDF]

Comparative Immunology Reports
Tankyrase (TNKS), a poly (ADP-ribose) polymerase (PARP) protein, mediates the PARylation of substrates, ultimately guiding them towards proteasome-dependent degradation or altering their localization.
Zhimin Li, Yashan Wu, Jian He, Kun Wu, Shaoping Weng, Changjun Guo, Jianguo He   +6 more
doaj   +2 more sources

Rapid, sensitive, and visual detection of mandarin fish ranavirus and infectious spleen and kidney necrosis virus using an RPA-CRISPR/Cas12a system [PDF]

Frontiers in Microbiology
Iridoviruses are large cytoplasmic icosahedral viruses that contain dsDNA. Among them, mandarin fish ranavirus (MRV) and infectious spleen and kidney necrosis virus (ISKNV) are particularly notable due to their high contagiousness and pathogenicity ...
Zhoutao Lu, Mincong Liang, Chuanrui Li, Yichun Xu, Shaoping Weng, Jianguo He, Changjun Guo   +6 more
doaj   +2 more sources

A novel viral SOCS from infectious spleen and kidney necrosis virus: interacts with Jak1 and inhibits IFN-α induced Stat1/3 activation. [PDF]

PLoS ONE, 2012
Interferon (IFN)-induced Janus kinase (Jak)/signal transducer and activator of transcription (Stat) pathway is important in controlling immune responses and is negatively response-regulated by the suppressor of cytokine signaling (SOCS) proteins. However,
Chang-Jun Guo, Li-Shi Yang, Ying-Fen Zhang, Yan-Yan Wu, Shao-Ping Weng, Xiao-Qiang Yu, Jian-Guo He   +6 more
doaj   +2 more sources

The viral TRAF protein (ORF111L) from infectious spleen and kidney necrosis virus interacts with TRADD and induces caspase 8-mediated apoptosis.

PLoS ONE, 2012
Infectious spleen and kidney necrosis virus (ISKNV) is the type species of the Megalocytivirus genus of the Iridoviridae family. It causes a serious and potentially pandemic disease in wild and cultured fishes.
Bai-Liang He, Ji-Min Yuan, Lu-Yun Yang, Jun-Feng Xie, Shao-Ping Weng, Xiao-Qiang Yu, Jian-Guo He   +6 more
doaj   +2 more sources

In field use of water samples for genomic surveillance of infectious spleen and kidney necrosis virus (ISKNV) infecting tilapia fish in Lake Volta, Ghana [PDF]

PeerJ
Viral outbreaks are a constant threat to aquaculture, limiting production for better global food security. A lack of diagnostic testing and monitoring in resource-limited areas hinders the capacity to respond rapidly to disease outbreaks and to prevent ...
Shayma Alathari, Andrew Joseph, Luis M. Bolaños, David J. Studholme, Aaron R. Jeffries, Patrick Appenteng, Kwaku A. Duodu, Eric B. Sawyerr, Richard Paley, Charles R. Tyler, Ben Temperton   +10 more
doaj   +3 more sources

Genotypic Characterization of <i>Infectious Spleen and Kidney Necrosis Virus</i> (ISKNV) in Southeast Asian Aquaculture. [PDF]

Transbound Emerg Dis, 2023
Infectious spleen and kidney necrosis virus (ISKNV) is a species within the genus Megalocytivirus (family Iridoviridae), which causes high mortality disease in many freshwater and marine fish species. ISKNV was first reported in Asia and is an emerging threat to aquaculture with increasing global distribution, in part due to its presence in ornamental ...
Fusianto CK, Becker JA, Subramaniam K, Whittington RJ, Koda SA, Waltzek TB, Murwantoko, Hick PM.   +7 more
europepmc   +3 more sources

First report of infectious spleen and kidney necrosis virus in Nile tilapia in Brazil [PDF]

Transboundary and Emerging Diseases, 2021
In June 2020, an atypical fatal outbreak in a Brazilian Nile tilapia farm was investigated. Twenty-three animals were collected and different tissues were used for bacterial isolation, histopathological and electron microscopic examination and viral detection using molecular methods.
Henrique César Pereira Figueiredo, Guilherme Campos Tavares, Fernanda Alves Dorella, Júlio César Câmara Rosa, Sóstenes Apolo Correia Marcelino, Felipe Pierezan, Felipe Luiz Pereira   +6 more
openaire   +3 more sources

Distribution and genotyping of infectious hematopoietic necrosis virus in farmed rainbow trout and autochthonous salmonids in North Macedonia

Macedonian Veterinary Review
Infectious hematopoietic necrosis (IHN) is a common disease in the intensive production of salmonids. The IHN virus (IHNV) was isolated for the first time in North Macedonia in 2018. This study aimed to investigate the distribution and genotype of IHN in
Aleksandar Traјchovski, Igor Djadjovski, Kiril Krstevski, Zagorka Popova-Hristovska, Martin Nikolovski, Ljubica Rashikj, Dimitar Bozinovski, Angela Grujovska, Niccolò Vendramin, Argelia Cuenca, Aleksandar Cvetkovikj   +10 more
doaj   +2 more sources

Infectious Spleen and Kidney Necrosis Virus ORF093R and ORF102R Regulate Glutamate Metabolic Reprogramming to Support Virus Proliferation by Interacting with c-Myc. [PDF]

Int J Mol Sci
Glutamine metabolism is essential for infectious spleen and kidney necrosis virus (ISKNV) replication. Glutaminase 1 (GLS1), the key enzyme of the glutamine metabolism, and c-Myc positively regulate ISKNV infection, while c-Myc is closely correlated with
Niu Y, Ye C, Lin Q, Liang H, Luo X, Ma B, Li N, Fu X.   +7 more
europepmc   +2 more sources

Examination of macroscopic and microscopic lesions in IBDV-infected organs and molecular characterization of IBDV VP1 gene fragments obtained from commercial broiler farms in Indonesia [PDF]

Veterinary World, 2023
Background and Aim: Infectious bursal disease (IBD) is an infectious immunosuppressive disease that affects young chickens. Instead of strict biosecurity practices, vaccination is used to control IBD. However, the disease has not been effectively managed.
Bernike Anggun Damairia, Khrisdiana Putri, Michael Haryadi Wibowo   +2 more
doaj   +1 more source