The potential role of microfilaments in host cells for infection with infectious spleen and kidney necrosis virus infection. [PDF]
Abstract Background Infectious spleen and kidney necrosis virus (ISKNV) belongs to the genus Megalocytivirus from the family Iridoviridae. Megalocytivirus causes severe economic losses to tropical freshwater and marine culture industry in Asian countries and is devastating to the mandarin fish farm industry in China ...
Jia KT +7 more
europepmc +4 more sources
The viral TRAF protein (ORF111L) from infectious spleen and kidney necrosis virus interacts with TRADD and induces caspase 8-mediated apoptosis. [PDF]
Infectious spleen and kidney necrosis virus (ISKNV) is the type species of the Megalocytivirus genus of the Iridoviridae family. It causes a serious and potentially pandemic disease in wild and cultured fishes.
Bai-Liang He +6 more
doaj +2 more sources
First report of infectious spleen and kidney necrosis virus in Nile tilapia in Brazil [PDF]
In June 2020, an atypical fatal outbreak in a Brazilian Nile tilapia farm was investigated. Twenty-three animals were collected and different tissues were used for bacterial isolation, histopathological and electron microscopic examination and viral detection using molecular methods.
Henrique César Pereira Figueiredo +6 more
openaire +3 more sources
Distribution and genotyping of infectious hematopoietic necrosis virus in farmed rainbow trout and autochthonous salmonids in North Macedonia [PDF]
Infectious hematopoietic necrosis (IHN) is a common disease in the intensive production of salmonids. The IHN virus (IHNV) was isolated for the first time in North Macedonia in 2018. This study aimed to investigate the distribution and genotype of IHN in
Aleksandar Traјchovski +10 more
doaj +2 more sources
Examination of macroscopic and microscopic lesions in IBDV-infected organs and molecular characterization of IBDV VP1 gene fragments obtained from commercial broiler farms in Indonesia [PDF]
Background and Aim: Infectious bursal disease (IBD) is an infectious immunosuppressive disease that affects young chickens. Instead of strict biosecurity practices, vaccination is used to control IBD. However, the disease has not been effectively managed.
Bernike Anggun Damairia +2 more
doaj +1 more source
New emerging viral disease on Giant Gourami (Osphronemus goramy Lac.) in Java, Indonesia [PDF]
This study investigates the role of pathogens in the disease outbreaks and mass mortality affecting giant gourami (Osphronemus goramy) populations from 2018 to 2020, leading to significant economic losses.
Taukhid Taukhid +4 more
doaj +1 more source
In 2016, famers reported mass mortality events in hybrid grouper within 2–4 weeks following transfer to sea cages on the northern coast of Bali. The objective was to obtain an aetiological diagnosis using a broad range of traditional and emerging ...
Cahya Fusianto +5 more
doaj +1 more source
Infectious Spleen and Kidney Necrosis Virus ORF093R and ORF102R Regulate Glutamate Metabolic Reprogramming to Support Virus Proliferation by Interacting with c-Myc. [PDF]
Glutamine metabolism is essential for infectious spleen and kidney necrosis virus (ISKNV) replication. Glutaminase 1 (GLS1), the key enzyme of the glutamine metabolism, and c-Myc positively regulate ISKNV infection, while c-Myc is closely correlated with
Niu Y +7 more
europepmc +2 more sources
Molecular epidemiology of Megalocytivirus in freshwater angelfish (Pterophyllum scalare) from Johor, Malaysia [PDF]
Background and Aim: Malaysia has more than 630 culturists who are involved in the ornamental fish industry and culture 250 species, including local and exotic species.
Che Azarulzaman Che Johan +3 more
doaj +1 more source
Under oxidative stress, viruses prefer glycolysis as an ATP source, and glutamine is required as an anaplerotic substrate to replenish the TCA cycle. Infectious spleen and kidney necrosis virus (ISKNV) induces reductive glutamine metabolism in the host ...
Xiaozhe Fu +7 more
doaj +1 more source

