Results 81 to 90 of about 3,384,034 (356)

Microbial Infections and Male Infertility [PDF]

open access: yes, 2016
Microbial infections can happen on a daily basis. There are specific microbial infections that are associated with the reproductive health. Infertility is a devastating health problem.
Jayaramasamy, Poongothai   +1 more
core   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

Genetic aspects of male infertility

open access: yesStudia Medyczne, 2015
Currently, infertility affects up to 140 million people worldwide. It is considered that the male factor is responsible for nearly a half of problems in obtaining pregnancy.
Bartosz Witczak   +2 more
doaj   +1 more source

Assisted Reproductive Technology and Newborn Size in Singletons Resulting from Fresh and Cryopreserved Embryos Transfer. [PDF]

open access: yesPLoS ONE, 2017
The aim of this study was two-fold: to investigate the association of Assisted Reproductive Technology (ART) and small newborn size, using standardized measures; and to examine within strata of fresh and cryopreserved embryos transfer, whether this ...
Galit Levi Dunietz   +11 more
doaj   +1 more source

Excitatory and inhibitory interactions affect the balance of chorus activity and energy efficiency in the aggregation of male frogs: Theoretical study using a hybrid dynamical model [PDF]

open access: yesarXiv, 2021
We theoretically study the role of excitatory and inhibitory interactions in the aggregations of male frogs. In most frogs, males produce sounds to attract conspecific females, which activates the calling behavior of other males and results in collective choruses.
arxiv  

Why Y chromosome is shorter and women live longer? [PDF]

open access: yesEur. Phys. J. B 65, 149-153 (2008), 2008
We have used the Penna ageing model to analyze how the differences in evolution of sex chromosomes depend on the strategy of reproduction. In panmictic populations, when females (XX) can freely choose the male partner (XY) for reproduction from the whole population, the Y chromosome accumulates defects and eventually the only information it brings is a
arxiv   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

Male Tract Microbiota and Male Infertility

open access: yesCells
In recent years, several studies have analyzed the composition of the male genital tract microbiota and its changes in infertility or in different situations associated with infertility.
Giuseppe Grande   +4 more
doaj   +1 more source

The role of number of copies, structure, behavior and copy number variations (CNV) of the Y chromosome in male infertility [PDF]

open access: yes, 2019
The World Health Organization (WHO) defines infertility as the inability of a sexually active, non-contracepting couple to achieve spontaneous pregnancy within one year. Statistics show that the two sexes are equally at risk.
Alessandro Porrello   +36 more
core   +1 more source

Clinical Evaluation of a Custom Gene Panel as a Tool for Precision Male Infertility Diagnosis by Next-Generation Sequencing [PDF]

open access: yes, 2020
Background: Up to 15% of couples are infertile and male factor infertility accounts for approximately 50% of these cases. Male infertility is a multifactorial pathological condition. The genetic of male infertility is very complex and at least 2000 genes
Aldo Eugenio Calogero   +9 more
core   +1 more source

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