Results 71 to 80 of about 361,626 (308)

Predictive factors of aneuploidy in infertile patients undergoing IVF: a retrospective analysis in a private IVF practice

Middle East Fertility Society Journal
Background PGT-A has become an important part of IVF treatments. Despite its increased use, there are contradicting results on its role in improving reproductive outcomes of ART cycles.
Anastasia A. Salame, Elias M. Dahdouh, Rania Aljafari, David A. Samuel, Bhavya P. Koodathingal, Aparna Bajpai, Shabin Kainoth, Michael Fakih   +7 more
doaj   +1 more source

The First Report of Successfully Pregnancy after ICSI with Combined DGC/Zeta Sperm Selection Procedure in a Couple with Eleven Repeated Fail IVF/ICSI Cycles [PDF]

International Journal of Fertility and Sterility, 2010
This is the first report implementing combined density gradient centrifugation/Zeta (DGC/Zeta) sperm selection procedure for a couple with eleven previous intra cytoplasmic sperm injection/ in vitro fertilization (ICSI/IVF) failure cycles. Semen analysis
Mohammad Reza Deemeh, Marziyeh Tavalaee, Seyed Mahdi Ahmadi, Seyed Asadolah Kalantari, Seyed Vali Alavi Nasab, Mohammad Hassan Najafi, Mohammad Hossein Nasr Esfahani   +6 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Trading-Off Reproductive Technology and Adoption: Does Subsidizing in Vitro Fertilization Decrease Adoption Rates and Should It Matter? [PDF]

, 2010
For those facing infertility, using assisted reproductive technology to have genetically related children is a very expensive proposition. In particular, to produce a live birth through in vitro fertilization (IVF) will cost an individual (on average ...
Chen, Daniel L., Cohen, I. Glenn
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Which transfer day results in the highest live birth rate for PCOS patients undergoing in vitro fertilization?

BMC Pregnancy and Childbirth, 2023
Background Polycystic ovary syndrome (PCOS) has unusual levels of hormones. The hormone receptors in the endometrium have a hostile effect and make the microenvironment unfavorable for embryo implantation.
Yuying Guo, Fangfang Dai, Bo Zheng, Linlin Tao, Tieqing Cui   +4 more
doaj   +1 more source

Embryo donation parents' attitudes towards donors : comparison with adoption [PDF]

, 2008
BACKGROUND: Embryo donation produces a family structure where neither rearing parent is genetically related to the child, as in adoption. It is not known how embryo donation parents view the donors compared with how adoptive parents view the birth ...
MacCallum, Fiona
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Decidualization of endometriosis in a cohort of IVF-mediated pregnancies

Scientific Reports, 2022
Decidualization is the process of endometrial change in pregnancy, a phenomenon that can involve also ovarian endometriomas. However, the frequency of this event remains unknown.
Francesca Filippi, Laura Benaglia, Federica Alagna, Irene La Vecchia, Rossella Biancardi, Marco Reschini, Edgardo Somigliana, Paolo Vercellini   +7 more
doaj   +1 more source

Ethics and Uncertainty: In Vitro Fertilization and Risks to Women\u27s Health [PDF]

, 1998
Dr. de Melo-Martin examines the risks, uncertainties and public policies surrounding in vitro fertilization and women\u27s health ...
de Melo-Martin, Inmaculada
core   +1 more source