Results 81 to 90 of about 361,626 (308)
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
1988-2008: Twenty years of BICA [PDF]
, 2008 The celebration of BICA’s twentieth anniversary in 2008 provides a timely opportunity to chart and review the Association’s achievements since its inception and, with an eye to the future, to identify continuing challenges - including those inherent in ...
Blyth, Eric
core
Use of Urinary Pregnanediol 3-glucuronide to Confirm Ovulation [PDF]
, 2013 Objective Urinary hormonal markers may assist in increasing the efficacy of Fertility Awareness Based Methods (FABM). This study uses urinary pregnanediol-3a-glucuronide (PDG) testing to more accurately identify the infertile phase of the menstrual cycle
Boehringer, H. +6 more
core +2 more sources
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Prevalence of depression among infertile couples in Iran: A meta-analysis study [PDF]
, 2013 Background: Several studies have been conducted in Iran in order to investigate the prevalence of depression among infertile couples. However, there is a remarkable diversity among the results.
Keramat, A. +3 more
core +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
DNA fragmentation index (DFI) as a measure of sperm quality and fertility in mice. [PDF]
, 2020 Although thousands of genetically modified mouse strains have been cryopreserved by sperm freezing, the likelihood of cryorecovery success cannot be accurately predicted using conventional sperm parameters.
Li, Ming-Wen, Lloyd, KC Kent
core +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Kallmann Syndrome in a 30-Year-Old Female With Primary Infertility: A Case Report
Case Reports in Obstetrics and GynecologyKallmann syndrome (KS) is a rare genetic disorder characterized by hypogonadotropic hypogonadism and anosmia. This case report highlights a 30-year-old woman with KS who presented with secondary amenorrhea and uterine hypoplasia after repeated use of ...
Arry Soryadharma +2 more
doaj +1 more source