Results 321 to 330 of about 197,632 (380)

Yimusake ameliorates corporal endothelial dysfunction by down-regulating the NLRP3 inflammasome-mediated NF-κB signaling pathway and inhibiting oxidative stress. [PDF]

Sex Med
Yang C, Zhang R, Zhu B, Niu L, Wang W, Jin X, Liu Y, Liu F.   +7 more
europepmc   +1 more source

Dexamethasone induced Dectin-1 activation enhances NLRP3 inflammasome activation. [PDF]

Front Immunol
Koerber RM, Oberbeck S, Kotthoff P, Daecke SN, Brossart P, Held SAE.   +5 more
europepmc   +1 more source

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

NLRP3 inflammasome and pyroptosis: implications in inflammation and multisystem disorders. [PDF]

PeerJ
Li X, Zhang Z, Han Y, Zhang M.
europepmc   +1 more source

The Inflammasome, an Innate Immunity Guardian, Participates in Skin Urticarial Reactions and Contact Hypersensitivity

, 2010
Naotomo Kambe, Yuumi Nakamura, Megumu K. Saito, Ryuta Nishikomori   +3 more
openalex   +1 more source

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

Loss of DJ-1 alleviates microglia-mediated neuroinflammation in Parkinson's disease via autophagy-lysosomal degradation of NLRP3. [PDF]

Front Immunol
Miao Q, Wang T, Wang H, Yu Y, Jin X.
europepmc   +1 more source

Surgical site infections and sepsis in gynecological surgery

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Despite advancements in infection control, surgical site infections (SSIs) and postoperative sepsis remain significant challenges in gynecological surgery, contributing to increased morbidity, mortality, and healthcare costs. In low‐income countries, circulatory failure due to septic shock leads to most deaths after surgery, with sepsis ...
Cristina Taliento, Gennaro Scutiero, Carmelia Milano, Mattia Grasso, Francesca Nitti, Orsola Brasile, Ruby Martinello, Giulia Bernardi, Stefano Restaino, Martina Arcieri, Matteo Pavone, Nicolò Bizzarri, Giuseppe Vizzielli, Pantaleo Greco   +13 more
wiley   +1 more source

Endotoxin tolerance inhibits NLRP3 inflammasome activation in macrophages of septic mice by restoring autophagic flux through TRIM26. [PDF]

Open Med (Wars)
Yang Y, Wu S, Lin M, Xie X, Shi H, Chen Y, Li S, Jiang Y, Zheng S, Shen C, Yang N, Lu M.   +11 more
europepmc   +1 more source

Stigmasterol attenuates atherosclerosis by inhibiting inflammatory signaling and foam cell formation

iMetaOmics, EarlyView.
Stigmasterol mitigates atherosclerotic plaque formation by modulating foam cell phenotypic alterations and cholesterol metabolism. Stigmasterol inhibits inflammatory CD86+ macrophage polarization via the NF‐κB/NLRP3 pathway and downregulates CD68 expression in smooth muscle cells (SMCs), contributing to reduced vascular inflammation.
Baiyi Lu, Fan Xiao, Qinjun Zhang, Yao Xie, Mengmeng Wang, Jesus Simal‐Gandara, Yan Liu, Thomas Efferth, Weisu Huang, Jianfu Shen, Jianbo Xiao   +10 more
wiley   +1 more source