Results 101 to 110 of about 56,139 (234)
Chronic inflammation triggered by the NLRP3 inflammasome in myeloid cells promotes growth plate dysplasia by mesenchymal cells [PDF]
, 2017 Skeletal complications are common features of neonatal-onset multisystem inflammatory disease (NOMID), a disorder caused by NLRP3-activating mutations. NOMID mice in which NLRP3 is activated globally exhibit several characteristics of the human disease ...
Abu-Amer, Yousef +8 more
core +2 more sources
Peripheral blood mitochondrial DNA content in relation to circulating metabolites and inflammatory markers: a population study [PDF]
, 2017 Mitochondrial DNA (mtDNA) content might undergo significant changes caused by metabolic derangements, oxidative stress and inflammation that lead to development and progression of cardiovascular diseases.
Brguljan-Hitij, Jana +13 more
core +1 more source
Deficiency of the purinergic receptor 2X7 attenuates nonalcoholic steatohepatitis induced by high-fat diet. possible role of the NLRP3 Inflammasome [PDF]
, 2017 Molecular mechanisms driving transition from simple steatosis to nonalcoholic steatohepatitis (NASH), a critical step in the progression of nonalcoholic fatty liver disease (NAFLD) to cirrhosis, are poorly defined. This study aimed at investigating the
Blasetti Fantauzzi, Claudia +6 more
core +3 more sources
Frontiers in Immunology, 2017 Outer membrane vesicles (OMVs) are proteoliposomes blebbed from the surface of Gram-negative bacteria. Chronic periodontitis is associated with an increase in subgingival plaque of Gram-negative bacteria, Porphyromonas gingivalis, Treponema denticola ...
Jessica D. Cecil +7 more
doaj +1 more source
Inflammasomes and Atherosclerosis
Cardiovascular Innovations and Applications, 2016 Inflammation plays an important role in atherosclerosis. Inflammasomes play a crucial role in innate immunity, which mediates the body’s response to various pathogens. Of the different types of inflammasomes, NLRP3 has been implicated in atherosclerosis through the production of proinflammatory cytokines, IL-1β and IL-18. This review describes the role
Yao Dai, J. L. Mehta, S. Vallurupalli
openaire +3 more sources
Involvement of Asc and Nlrp3 inflammasomes in the testes following spinal cord injury
Endocrine Regulations, 2020 Objective. The exact mechanism, by which spinal cord injury (SCI) leads to a male subfertility is not well-known. Present study was conducted to determine the mechanisms that lead to the elevated end-product cytokines and inflammasomes in the testes of ...
Ramezanikhah Hajar +5 more
doaj +1 more source
Deciphering Inflammasome Mechanisms in Periodontal Diseases: A Review
Archives of Medicine and Health SciencesInflammasomes are complex multimeric protein molecules that play a central role in orchestrating the inflammatory response within periodontal tissues.
Himani Sharma +2 more
doaj +1 more source
The Role of AIM2 Inflammasome in Knee Osteoarthritis
Journal of Inflammation Research, 2022 Jiyong Yang,1 Wengang Liu2 1The Fifth Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, 510095, People’s Republic of China; 2Guangdong Second Traditional Chinese Medicine Hospital, Guangzhou, 510095, People’s Republic of ...
Yang J, Liu W
doaj
Vaccines, 2014 The potent adjuvant activity of the novel adjuvant, poly[di(sodiumcarboxylatoethylphenoxy)phosphazene] (PCEP), with various antigens has been reported previously. However, very little is known about its mechanisms of action.
Sunita Awate +4 more
doaj +1 more source