Results 361 to 370 of about 90,432 (374)
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Inflammasomes in the Kidney

2018
Inflammasomes influence a diverse range of kidney disease, including acute and chronic kidney diseases, and those mediated by innate and adaptive immunity. Both IL-18 and in particular IL-1β are validated therapeutic targets in several kidney diseases.
A. Richard Kitching   +2 more
openaire   +3 more sources

Emerging insights into molecular mechanisms underlying pyroptosis and functions of inflammasomes in diseases

Journal of Cellular Physiology, 2019
Pyroptosis is a form of necrotic and inflammatory programmed cell death, which could be characterized by cell swelling, pore formation on plasma membranes, and release of proinflammatory cytokines (IL‐1β and IL‐18).
Fangfang Lu   +6 more
semanticscholar   +1 more source

Measuring the Inflammasome

2011
Inflammasomes are multiprotein complexes whose activity has been implicated in physiological and pathological inflammation. The hallmarks of inflammasome activation are the secretion of the mature forms of Caspase-1 and IL-1β from cells of the innate immune system.
openaire   +3 more sources

Atypical Inflammasomes

2016
Pattern recognition receptors, including members of the NLR and PYHIN families, are essential for recognition of both pathogen- and host-derived danger signals. A number of molecules in these families are capable of forming multiprotein complexes termed inflammasomes that result in the activation of caspase-1.
Ann M, Janowski, Fayyaz S, Sutterwala
openaire   +2 more sources

The role of inflammasomes in kidney disease

Nature Reviews Nephrology, 2019
T. Komada, D. Muruve
semanticscholar   +1 more source

Inflammasome

2020
Tao Gong, Rongbin Zhou
openaire   +1 more source

Central roles of NLRs and inflammasomes in viral infection

Nature Reviews Immunology, 2010
Thirumala-Devi Kanneganti
exaly  

Sensing and reacting to microbes through the inflammasomes

Nature Immunology, 2012
Gabriel Núñez
exaly  

The Inflammasomes and Autoinflammatory Syndromes

Annual Review of Pathology: Mechanisms of Disease, 2015
Lori Broderick   +2 more
exaly  

Inflammasomes in carcinogenesis and anticancer immune responses

Nature Immunology, 2012
Laurence Zitvogel   +2 more
exaly  

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