Results 51 to 60 of about 3,799,228 (259)
Mitochondrial control of inflammation
Nature reviews. Immunology, 2022 Numerous mitochondrial constituents and metabolic products can function as damage-associated molecular patterns (DAMPs) and promote inflammation when released into the cytosol or extracellular milieu.
S. Marchi +4 more
semanticscholar +1 more source
Joint Explicit and Implicit Cross-Modal Interaction Network for Anterior Chamber Inflammation Diagnosis [PDF]
arXiv, 2023 Uveitis demands the precise diagnosis of anterior chamber inflammation (ACI) for optimal treatment. However, current diagnostic methods only rely on a limited single-modal disease perspective, which leads to poor performance. In this paper, we investigate a promising yet challenging way to fuse multimodal data for ACI diagnosis.
arxiv
The in silico macrophage: toward a better understanding of inflammatory disease [PDF]
Genome Medicine 2011, 3:4 (22 January 2011), 2011 Macrophages function as sentinel, cell-regulatory hubs capable of initiating, perpetuating and contributing to the resolution of an inflammatory response, following their activation from a resting state. Highly complex and varied gene expression programs within the macrophage enable such functional diversity.
arxiv +1 more source
Contemporary views on inflammatory pain mechanisms: TRPing over innate and microglial pathways. [PDF]
, 2016 Tissue injury, whether by trauma, surgical intervention, metabolic dysfunction, ischemia, or infection, evokes a complex cellular response (inflammation) that is associated with painful hyperalgesic states.
Guan, Zhonghui +2 more
core +2 more sources
Role of pyroptosis in inflammation and cancer
Cellular & Molecular Immunology, 2022 Pyroptosis is a form of programmed cell death mediated by gasdermin and is a product of continuous cell expansion until the cytomembrane ruptures, resulting in the release of cellular contents that can activate strong inflammatory and immune responses ...
Xiang Wei +9 more
semanticscholar +1 more source
Apoptosis and inflammation [PDF]
Mediators of Inflammation, 1995 During the last few decades it has been recognized that cell death is not the consequence of accidental injury, but is the expression of a cell suicide programme. Kerr et al. (1972) introduced the term apoptosis. This form of cell death is under the influence of hormones, growth factors and cytokines, which depending upon the receptors present on the ...
I. Vermes, C. Haanen
openaire +3 more sources
Inflammation-driven glial alterations in the cuprizone mouse model probed with diffusion-weighted magnetic resonance spectroscopy at 11.7 T [PDF]
arXiv, 2020 Inflammation of brain tissue is a complex response of the immune system to the presence of toxic compounds or to cell injury, leading to a cascade of pathological processes that include glial cell activation. Noninvasive magnetic resonance imaging markers of glial reactivity would be very useful for in vivo detection and monitoring of inflammation ...
arxiv
Acute neuroinflammation induces AIS structural plasticity in a NOX2-dependent manner [PDF]
, 2017 Background Chronic microglia-mediated inflammation and oxidative stress are well-characterized underlying factors in neurodegenerative disease, whereby reactive inflammatory microglia enhance ROS production and impact neuronal integrity. Recently, it has
Benusa, S. D. +4 more
core +1 more source
Targeting crosstalk between Nrf-2, NF-κB and androgen receptor signaling in prostate cancer [PDF]
, 2018 Oxidative stress, inflammation and androgen receptor (AR) signaling play a pivotal role in the initiation, development and progression of prostate cancer (PCa).
Khurana, Namrata, Sikka, Suresh C
core +2 more sources
Diabetes, 2008 OBJECTIVE—Diabetes and obesity are characterized by a low-grade inflammation whose molecular origin is unknown. We previously determined, first, that metabolic endotoxemia controls the inflammatory tone, body weight gain, and diabetes, and second, that ...
Patrice D Cani +6 more
semanticscholar +1 more source