Results 61 to 70 of about 2,394,340 (295)

Role of IL-17A, IL-17F, and the IL-17 Receptor in Regulating Growth-Related Oncogene-α and Granulocyte Colony-Stimulating Factor in Bronchial Epithelium: Implications for Airway Inflammation in Cystic Fibrosis [PDF]

, 2005
Florencia McAllister, Adam C. Henry, James L. Kreindler, Patricia J. Dubin, Lauren Ulrich, Chad Steele, Jonathan D. Finder, Joseph M. Pilewski, Beatriz M. Carreno, Samuel J. Goldman, Jaana Pirhonen, Jay K. Kolls   +11 more
openalex   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Interferon α2 and interferon γ induce the degranulation independent production of VEGF‐A and IL‐1 receptor antagonist and other mediators from human mast cells

Immunity, Inflammation and Disease, 2018
Background Mast cells are resident immune effector cells, often studied in the context of allergic disease. Found in substantial numbers at sites of potential infection they are increased at sites of angiogenesis and can be pivotal for the sensing and ...
Sharon A. Oldford, Suzanne P. Salsman, Liliana Portales‐Cervantes, Raidan Alyazidi, Robert Anderson, Ian D Haidl, Jean S. Marshall   +6 more
doaj   +1 more source

Loss of CD4+ T Cell IL-6R Expression during Inflammation Underlines a Role for IL-6TransSignaling in the Local Maintenance of Th17 Cells [PDF]

, 2010
Gareth W. Jones, Rachel M. McLoughlin, Victoria J. Hammond, Clare R. Parker, John D. Williams, Raj Malhotra, Jürgen Scheller, Anwen S. Williams, Stefan Rose‐John, Nicholas Topley, Simon A. Jones   +10 more
openalex   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Red blood cells induce hypoxic lung inflammation [PDF]

, 2008
Rainer Kiefmann, Joseph M. Rifkind, Enika Nagababu, Jahar Bhattacharya   +3 more
openalex   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Gut microbiota modulates CNS barrier function in murine model for multiple sclerosis

Fluids and Barriers of the CNS
Multiple sclerosis (MS) is a chronic inflammatory disease that has been associated with dysfunction of the protective barriers in the central nervous system (CNS), allowing harmful immune cells to enter.
Junhua Xie, Marlies Burgelman, Pieter Dujardin, Jonas Castelein, Griet Van Imschoot, Elien Van Wonterghem, Hannah Lernout, Sjoerd T. T. Schetters, Charysse Vandendriessche, Lien Van Hoecke, Roosmarijn E. Vandenbroucke   +10 more
doaj   +1 more source

Dimethyl fumarate ameliorates hepatic inflammation in alcohol related liver disease [PDF]

, 2020
Moris Sangineto, Felix Grabherr, Timon E. Adolph, Christoph Grander, Simon Reider, Nikolai Jaschke, Lisa Mayr, Julian Schwärzler, Marcello Dallio, Alexander R. Moschen, Antonio Moschetta, Carlo Sabbà, Herbert Tilg   +12 more
openalex   +1 more source

Role of Oxidative Stress in Vascular Low-Grade Inflammation Initiation Due to Acute Salt Loading in Young Healthy Individuals [PDF]

, 2022
Ana Knezović, Nikolina Kolobarić, Ines Drenjančević, Zrinka Mihaljević, Petar Šušnjara, Ivana Jukić, Marko Stupin, Aleksandar Kibel, Saška Marczi, Martina Mihalj, Ana Stupin   +10 more
openalex   +1 more source