Results 161 to 170 of about 158,758 (202)
The Role of CLCA Proteins in Inflammatory Airway Disease [PDF]
Annual Review of Physiology, 2009 Inflammatory airway diseases such as asthma and chronic obstructive pulmonary disease (COPD) exhibit stereotyped traits that are variably expressed in each person. In experimental mouse models of chronic lung disease, these individual disease traits can be genetically segregated and thereby linked to distinct determinants.
Anand C Patel +2 more
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The Spectrum of Airway Involvement in Inflammatory Bowel Disease
Clinics in Chest Medicine, 2022Inflammatory bowel disease is associated with a wide spectrum of central, large, and small airway abnormalities, including bronchiectasis. The bronchiectasis associated with inflammatory bowel disease has a distinct phenotype, with marked inflammation and at times severe sterile bronchorrhea that can be responsive to inhaled corticosteroids.
Philippe Camus, Thomas V Colby
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B lymphocytes in inflammatory airway diseases
Clinical & Experimental Allergy, 2010SummaryB lymphocytes are key players in all facets of adaptive immune responses and are responsible for the production of IgE antibodies, initiators of allergic hypersensitivity reactions. Recent evidence indicates that B cells may be a crucial player in allergic and inflammatory airway pathology, directly populating upper and lower airway tissues ...
J-P, Drolet +5 more
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A review of inflammatory mechanism in airway diseases
Inflammation Research, 2018Inflammation in the lung is the body's natural response to injury. It acts to remove harmful stimuli such as pathogens, irritants, and damaged cells and initiate the healing process. Acute and chronic pulmonary inflammation are seen in different respiratory diseases such as; acute respiratory distress syndrome, chronic obstructive pulmonary disease ...
Parya, Aghasafari +2 more
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Antileukotrienes in Upper Airway Inflammatory Diseases
Current Allergy and Asthma Reports, 2015Leukotrienes (LTs) are a family of inflammatory mediators including LTA4, LTB4, LTC4, LTD4, and LTE4. By competitive binding to the cysteinyl LT1 (CysLT1) receptor, LT receptor antagonist drugs, such as montelukast, zafirlukast, and pranlukast, block the effects of CysLTs, improving the symptoms of some chronic respiratory diseases, particularly ...
Cemal, Cingi +3 more
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Airway nerves and dyspnea associated with inflammatory airway disease
Respiratory Physiology & Neurobiology, 2009The neurobiology of dyspnea is varied and complex, but there is little doubt that vagal nerves within the airways are capable of causing or modulating some dyspneic sensations, especially those associated with inflammatory airway diseases. A major contributor to the dyspnea associated with inflammatory airway disease is explained by airway narrowing ...
Bradley J, Undem, Christina, Nassenstein
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Novel therapies for the treatment of inflammatory airway disease
Expert Opinion on Investigational Drugs, 2003Asthma and chronic obstructive pulmonary disease (COPD) are diseases of the airways with an underlying inflammatory component. The prevalence and healthcare burden of asthma and COPD is still rising and is predicted to continue to rise in the current century.
Maria G Belvisi
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Large Airway Disease Associated With Inflammatory Bowel Disease
Chest, 1998Lung disease is a rare complication of inflammatory bowel disease (IBD). Herein is a series of seven IBD patients who developed new, persistent and unexplained symptoms of respiratory disease, particularly chronic productive cough. Using a CT scan of the chest, a diagnosis of bronchiectasis was made in five patients, while the diagnosis of chronic ...
A, Spira, R, Grossman, M, Balter
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Role of Mitochondrial DNA in Inflammatory Airway Diseases
Comprehensive Physiology, 2021Abstract The mitochondrial genome is a small, circular, and highly conserved piece of DNA which encodes only 13 protein subunits yet is vital for electron transport in the mitochondrion and, therefore, vital for the existence of multicellular life on Earth.
Ryan J, Snyder, Steven R, Kleeberger
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Nonmicrobial-mediated inflammatory airway diseases—an update
Journal of Physiology and Biochemistry, 2013In lungs, airways are in constant contact with air, microbes, allergens, and environmental pollutants. The airway epithelium represents the first line of lung defense through different mechanisms, which facilitate clearance of inhaled pathogens and environmental particles while minimizing an inflammatory response.
Polani B, Ramesh Babu, P, Krishnamoorthy
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