Results 151 to 160 of about 6,114,519 (189)

Antileukotrienes in Upper Airway Inflammatory Diseases

Current Allergy and Asthma Reports, 2015
Leukotrienes (LTs) are a family of inflammatory mediators including LTA4, LTB4, LTC4, LTD4, and LTE4. By competitive binding to the cysteinyl LT1 (CysLT1) receptor, LT receptor antagonist drugs, such as montelukast, zafirlukast, and pranlukast, block the effects of CysLTs, improving the symptoms of some chronic respiratory diseases, particularly ...
Sahin, Ethem, Ipci, Kagan, MULUK, NURAY BAYAR, CİNGİ, CEMAL   +3 more
openaire   +3 more sources

Airway nerves and dyspnea associated with inflammatory airway disease

Respiratory Physiology & Neurobiology, 2009
The neurobiology of dyspnea is varied and complex, but there is little doubt that vagal nerves within the airways are capable of causing or modulating some dyspneic sensations, especially those associated with inflammatory airway diseases. A major contributor to the dyspnea associated with inflammatory airway disease is explained by airway narrowing ...
Bradley J, Undem, Christina, Nassenstein
openaire   +2 more sources

Large Airway Disease Associated With Inflammatory Bowel Disease

Chest, 1998
Lung disease is a rare complication of inflammatory bowel disease (IBD). Herein is a series of seven IBD patients who developed new, persistent and unexplained symptoms of respiratory disease, particularly chronic productive cough. Using a CT scan of the chest, a diagnosis of bronchiectasis was made in five patients, while the diagnosis of chronic ...
A, Spira, R, Grossman, M, Balter
openaire   +2 more sources

Update on Noninfectious Inflammatory Diseases of the Lower Airway

Veterinary Clinics of North America Equine Practice, 2015
Inflammatory airway disease and recurrent airway obstruction are 2 nonseptic diseases of the equine respiratory system with a shared cause of exposure to particulate matter. They appear to occupy 2 ends of a spectrum of disease, but are differentiated by history, clinical signs, and response to treatment.
Melissa R Mazan
exaly   +3 more sources

Role of Mitochondrial DNA in Inflammatory Airway Diseases

Comprehensive Physiology, 2021
Abstract The mitochondrial genome is a small, circular, and highly conserved piece of DNA which encodes only 13 protein subunits yet is vital for electron transport in the mitochondrion and, therefore, vital for the existence of multicellular life on Earth.
Ryan J, Snyder, Steven R, Kleeberger
openaire   +2 more sources

Nonmicrobial-mediated inflammatory airway diseases—an update

Journal of Physiology and Biochemistry, 2013
In lungs, airways are in constant contact with air, microbes, allergens, and environmental pollutants. The airway epithelium represents the first line of lung defense through different mechanisms, which facilitate clearance of inhaled pathogens and environmental particles while minimizing an inflammatory response.
Polani B, Ramesh Babu, P, Krishnamoorthy
openaire   +2 more sources

Chronic Macrolide Therapy in Inflammatory Airways Diseases

Chest, 2010
Long-term therapy with the macrolide antibiotic erythromycin was shown to alter the clinical course of diffuse panbronchiolitis in the late 1980s. Since that time, macrolides have been found to have a large number of antiinflammatory properties in addition to being antimicrobials.
Adam L, Friedlander, Richard K, Albert
openaire   +2 more sources

Nanotechnology-Based Therapeutics for Airway Inflammatory Diseases

Clinical Reviews in Allergy and Immunology
Abstract Under the concept of “one airway, one disease”, upper and lower airway inflammatory diseases share similar pathogenic mechanisms and are collectively referred to as airway inflammatory diseases. With industrial development and environmental changes, the incidence of these diseases has gradually increased.
Xicheng Song, Hongfei Zhao, Yujuan Yang
exaly   +3 more sources

Nitric oxide in upper airways inflammatory diseases

Inflammation Research, 2007
In the human respiratory tract, the main production sites of exhaled nitric oxide (NO) are the nose and paranasal sinuses. In the upper airways, NO has been suggested to be involved at different levels with regulatory, protective, defensive or deleterious effects.
Mauro Maniscalco, Matteo Sofia, Girolamo Pelaia   +2 more
openaire   +3 more sources

The Spectrum of Nonasthmatic Inflammatory Airway Diseases in Adults

Otolaryngologic Clinics of North America, 2010
When the airways are overwhelmed by noxious particles, gases, or microorganisms, inflammatory and immune responses occur that may cause permanent structural changes. One consequence may be an overproduction of mucus and this may overwhelm mucociliary clearance mechanisms and cause a chronic cough phlegm syndrome. The expectorated mucus is usually clear
Sidney S, Braman, Muhanned, Abu-Hijleh
openaire   +2 more sources