Results 91 to 100 of about 387,427 (329)

Gastrointestinal Perforation as a Safety Concern Among Patients With Rheumatoid Arthritis Receiving JAK Inhibitor Therapy: A Systematic Review and Network Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective Gastrointestinal perforation (GIP) is a rare and life‐threatening safety concern associated with JAK inhibitors (JAKi). We aimed to review the evidence regarding the risk of GIP associated with the use of JAKi in patients with rheumatoid arthritis (RA) using a systematic review and network meta‐analysis approach.
Thipsukhon Sathapanasiri, Manuel Meraz, Hamraz Mokri, Sajesh K Veettil, Karn Wijarnpreecha, Naomi Schlesinger, Arthur Kavanaugh, Nathorn Chaiyakunapruk   +7 more
wiley   +1 more source

Recommendations for the Use of Disease‐Modifying Antirheumatic Drugs in Pregnancy and Reproductive Health for Patients With Rheumatic Disease: A Scoping Review

Arthritis Care &Research, EarlyView.
Objective Autoimmune rheumatic diseases commonly affect individuals of childbearing age, with historically increased adverse pregnancy outcomes in this group. The advent of disease‐modifying antirheumatic drugs (DMARDs) has fostered more suitable conditions for pregnancy; however, this is accompanied by challenges in ensuring safe use in reproductive ...
Athena Chin, Alice Terrett, Mihye Kwon, Samuel Whittle, Catherine Hill   +4 more
wiley   +1 more source

Caveolin-1 Scaffolding Domain Peptide Regulates Colon Endothelial Cell Survival through JNK Pathway

International Journal of Inflammation, 2020
It has been reported that pathological angiogenesis contributes to both experimental colitis and inflammatory bowel disease. Recently, we demonstrated that endothelial caveolin-1 plays a key role in the pathological angiogenesis of dextran sodium sulfate
Kai Fang, Christopher G. Kevil
doaj   +1 more source

Characterization of the fecal microbiome in cats with inflammatory bowel disease or alimentary small cell lymphoma. [PDF]

, 2019
Feline chronic enteropathy (CE) is a common gastrointestinal disorder in cats and mainly comprises inflammatory bowel disease (IBD) and small cell lymphoma (SCL).
Ackermann, Mark R, Chow, Betty, Estep, J Scot, Hill, Steve L, Lidbury, Jonathan A, Marsilio, Sina, Pilla, Rachel, Sarawichitr, Benjamin, Steiner, Joerg M, Suchodolski, Jan S   +9 more
core   +1 more source

Clinical performance of an infliximab rapid quantification assay [PDF]

, 2017
Background: Therapeutic drug monitoring (TDM)-based algorithms can be used to guide infliximab (IFX) adjustments in inflammatory bowel disease (IBD) patients.
Afonso, Joana, Andrade, Patrícia, Caldeira, Paulo, Carneiro, Fátima, Carvalho, Diana, Coelho, Rosa, Dias, Cláudia Camila, Geboes, Karel, Gonçalves, Ana Rita, Gonçalves, Raquel, Lago, Paula, Lopes, Joanne, Lopes, Susana, Magro, Fernando, Meira, Tania, Ministro, Paula, Ramos, Jaime, Rosa, Isadora, Soares, João-Bruno, Sousa, Helena Tavares, Sousa, Paula, Vieira, Ana Isabel   +21 more
core   +2 more sources

Agreement of administrative pharmacy dispensing with self‐reported use of oral prednisone in US Veterans with rheumatoid arthritis

Arthritis Care &Research, Accepted Article.
Objective Administrative claims are used to evaluate oral glucocorticoid use in rheumatoid arthritis (RA), despite limited evidence to support accuracy. We aimed to evaluate the performance of claims‐based algorithms for glucocorticoid use compared to self‐report in an RA population.
Beth I. Wallace, Bryant R. England, Joshua F. Baker, Michael D. George, Brian C. Sauer, Jorge Rojas, Punyasha Roul, Katherine D. Wysham, Hannah Brubeck, Isaac Smith, Liron Caplan, Paul A. Monach, Gail S. Kerr, Gary Kunkel, Tawnie Braaten, Ted R. Mikuls, Grant W. Cannon   +16 more
wiley   +1 more source

The therapeutic management of gut barrier leaking: the emerging role for mucosal barrier protectors [PDF]

, 2015
OBJECTIVE: Gut barrier is a functional unit organized as a multi-layer system and its multiple functions are crucial for maintaining gut homeostasis. Numerous scientific evidences showed a significant association between gut barrier leaking and gastro ...
Bruno, G, Franceschi, F, Gasbarrini, A, Lopetuso, Lr, Petito, V, Scaldaferri, F   +5 more
core  

NOD2 and inflammation: current insights [PDF]

, 2018
The nucleotide-binding oligomerization domain (NOD) protein, NOD2, belonging to the intracellular NOD-like receptor family, detects conserved motifs in bacterial peptidoglycan and promotes their clearance through activation of a proinflammatory ...
Cucchiara, Salvatore, Negroni, Anna, Pierdomenico, Maria, Stronati, Laura   +3 more
core   +2 more sources

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Overcoming cancer risk in inflammatory bowel disease: new insights into preventive strategies and pathogenesis mechanisms including interactions of immune cells, cancer signaling pathways, and gut microbiota

Frontiers in Immunology
Inflammatory bowel disease (IBD), characterized primarily by gastrointestinal inflammation, predominantly manifests as Crohn’s disease (CD) and ulcerative colitis (UC).
Haonan Zhang, Yulu Shi, Chanchan Lin, Chengcheng He, Shanping Wang, Qingyuan Li, Yan Sun, Mingsong Li   +7 more
doaj   +1 more source