Results 31 to 40 of about 3,411,578 (286)

CARMIL2 Deficiency Presenting as Very Early Onset Inflammatory Bowel Disease [PDF]

open access: yes, 2019
Background: Children with very early onset inflammatory bowel diseases (VEO-IBD) often have a refractory and severe disease course. A significant number of described VEO-IBD-causing monogenic disorders can be attributed to defects in immune-related genes.
Conca, Raffaele   +101 more
core   +1 more source

Analysis of IL12B gene variants in inflammatory bowel disease [PDF]

open access: yes, 2012
IL12B encodes the p40 subunit of IL-12, which is also part of IL-23. Recent genome-wide association studies identified IL12B and IL23R as susceptibility genes for inflammatory bowel disease (IBD).
Darina Czamara   +79 more
core   +2 more sources

Features of Crohn's Disease Depending on the Age of Disease Onset

open access: yesРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии, 2023
Aim: to evaluate the characteristics of Crohn's disea depending on the age of the disease onset in patients observed in a specialized City Center for Inflammatory Bowel Diseases Diagnosis and Treatment.Materials and methods. We observed 180 patients with
E. G. Ganich, O. B. Shchukina
doaj   +1 more source

Bacteroides thetaiotaomicron Ameliorates Colon Inflammation in Preclinical Models of Crohn's Disease [PDF]

open access: yes, 2019
SUPPLEMENTARY DATA: Supplementary data is available at Inflammatory Bowel Diseases onlinePeer ...
Logan, Elizabeth T   +3 more
core   +1 more source

Two Worlds, One Life: Narrative Spaces of Identity Between Health and Illness [PDF]

open access: yes, 2009
This paper reports a component of a larger study about how adolescents adapt to chronic illness. The condition in question was Inflammatory Bowel Disease (IBD), a medical term for two conditions, ulcerative colitis and Crohn’s disease. Ulcerations appear
Gross, Harriet   +2 more
core   +4 more sources

Substance P Mediates Proinflammatory Cytokine Release From Mesenteric Adipocytes in Inflammatory Bowel Disease PatientsSummary

open access: yesCellular and Molecular Gastroenterology and Hepatology, 2015
Background & Aims: Substance P (SP) neurokinin-1 receptors (NK-1Rs) are expressed in mesenteric preadipocytes, and SP binding activates proinflammatory signaling in these cells. We evaluated the expression levels of SP (Tac-1), NK-1R (Tacr-1), and NK-2R (
Aristea Sideri   +9 more
doaj   +1 more source

Mesenteric excision surgery or conservative limited resection in Crohn’s disease: study protocol for an international, multicenter, randomized controlled trial

open access: yesTrials, 2020
Background The structures of the mesentery including adipose tissue, nerves, and lymphatics play an important role in the pathogenesis and disease progression of Crohn’s disease (CD).
Yi Li   +9 more
doaj   +1 more source

Identification of a Novel Substance P–Neurokinin-1 Receptor MicroRNA-221-5p Inflammatory Network in Human Colonic Epithelial CellsSummary

open access: yesCellular and Molecular Gastroenterology and Hepatology, 2015
Background & Aims: Substance P (SP), a neuropeptide member of the tachykinin family, plays a critical role in colitis. MicroRNAs (miRNAs) are small noncoding RNAs that negatively regulate gene expression.
Kai Fang   +6 more
doaj   +1 more source

Factors associated with decreased bone mineral density in patients with Crohn's disease

open access: yes, 2021
sem informação231S11S12Advances-in-Inflammatory-Bowel-Diseases-Crohn's-and-Colitis Foundation's National Clinical and Research Conference2016-12-08Orlando, FL, Estados Unidossem ...
Claudio, Coy   +8 more
core   +1 more source

Inflammatory bowel disease [PDF]

open access: yesArchives of Disease in Childhood, 2006
Twenty five per cent of inflammatory bowel disease presents in childhood. Growth and nutrition are key issues in the management with the aim of treatment being to induce and then maintain disease remission with minimal side effects. Only 25% of Crohn's disease presents with the classic triad of abdominal pain, weight loss, and diarrhoea.
R M, Beattie   +4 more
openaire   +2 more sources

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