Results 41 to 50 of about 1,070,166 (331)

CT enterography for evaluation of disease activity in patients with ileocolonic Crohn's disease

BMC Gastroenterology, 2022
Background CT enterography (CTE) is used routinely for assessment of activity and severity in Crohn's disease (CD), but there are few CTE scoring systems.
Jinlu Tong, Qi Feng, Chenpeng Zhang, Xitao Xu, Zhihua Ran   +4 more
doaj   +1 more source

Diagnosis, prevalence, and outcomes of sarcopenia in kidney transplantation recipients: A systematic review and meta‐analysis

Journal of Cachexia, Sarcopenia and Muscle, 2023
The prevalence of sarcopenia and its clinical predictors and clinical impact vary among kidney transplant recipients (KTRs), in part because of different diagnostic criteria.
Jin‐Zhi Zhang, Wei Shi, Min Zou, Qi‐Shan Zeng, Yue Feng, Zhen‐Yi Luo, Hua‐Tian Gan   +6 more
doaj   +1 more source

Enteroendocrine Cells: Sensing Gut Microbiota and Regulating Inflammatory Bowel Diseases.

Inflammatory Bowel Diseases, 2019
Host sensing in the gut microbiota has been crucial in the regulation of intestinal homeostasis. Although inflammatory bowel diseases (IBDs), multifactorial chronic inflammatory conditions of the gastrointestinal tract, have been associated with ...
Yanbo Yu, Wenjing Yang, Yanqing Li, Y. Cong   +3 more
semanticscholar   +1 more source

Biomarkers as Potential Treatment Targets in Inflammatory Bowel Disease: A Systematic Review

Canadian Journal of Gastroenterology and Hepatology, 2015
There is increasing interest in the concept of ‘treat-to-target’ in inflammatory bowel disease as a mechanism to standardize management and prevent complications. While clinical, radiographic and endoscopic treatment end points will figure prominently in
Travis B Murdoch, Sarah O’Donnell, Mark S Silverberg, Remo Panaccione   +3 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Influence of Genetics, Immunity and the Microbiome on the Prognosis of Inflammatory Bowel Disease (IBD Prognosis Study): the protocol for a Copenhagen IBD Inception Cohort Study

BMJ Open, 2022
Introduction Inflammatory bowel diseases (IBD), encompassing Crohn’s disease and ulcerative colitis, are chronic, inflammatory diseases of the gastrointestinal tract.
Johan Burisch, Lene Terslev, Mikkel Østergaard, Annette Bøjer Jensen, Frank Krieger Jensen, Flemming Bendtsen, Charlotte Wiell, Mohamed Attauabi, Klaus Theede, Viktoria Fana, Hartwig Roman Siebner, Henrik S Thomsen, Jakob M Møller, Simon Francis Thomsen, Gorm Roager Madsen, Anne Vibeke Wewer, Rune Wilkens, Johan Ilvemark, Nora Vladimirova, Sanja Bay Hansen, Yousef Jesper Wirenfeldt Nielsen, Helene Andrea Sinclair Ingels, Trine Boysen, Jacob T Bjerrum, Christian Jakobsen, Maria Dorn-Rasmussen, Sabine Jansson, Yiqiu Yao, Ewa Anna Burian, Frederik Trier Møller, Kristina Bertl, Andreas Stavropoulos, Jakob B Seidelin   +32 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Risk of Serious and Opportunistic Infections Associated With Treatment of Inflammatory Bowel Diseases.

Gastroenterology, 2018
BACKGROUND & AIMS The risk of infection associated with tumor necrosis factor antagonists (anti-TNF) and thiopurines (combination therapy) is uncertain.
J. Kirchgesner, M. Lemaitre, F. Carrat, Mahmoud Zureik, F. Carbonnel, R. Dray-Spira   +5 more
semanticscholar   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source