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Inflammatory processes in muscle injury and repair

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 2005
Modified muscle use or injury can produce a stereotypic inflammatory response in which neutrophils rapidly invade, followed by macrophages. This inflammatory response coincides with muscle repair, regeneration, and growth, which involve activation and proliferation of satellite cells, followed by their terminal differentiation.
James G Tidball
openaire   +4 more sources

A reversible epigenetic memory of inflammatory injury controls lineage plasticity and tumor initiation in the mouse pancreas.

Developmental Cell, 2023
Inflammation is essential to the disruption of tissue homeostasis and can destabilize the identity of lineage-committed epithelial cells. Here, we employ lineage-traced mouse models, single-cell transcriptomic and chromatin analyses, and CUT&TAG to ...
David Falvo   +16 more
semanticscholar   +1 more source

Dihydromyricetin suppresses inflammatory injury in microglial cells to improve neurological behaviors of Alzheimer's disease mice via the TLR4/MD2 signal.

International Immunopharmacology, 2023
AIM We analyzed the role and mechanism of dihydromyricetin (DHM) in suppressing inflammatory injury in microglial cells via targeting MD2. METHODS In vitro, BV2 cells were used as the objects of study to induce inflammatory injury with LPS + ATP, then ...
Hongyan Pei   +4 more
semanticscholar   +1 more source

Lower Airway Dysbiosis Augments Lung Inflammatory Injury in Mild-to-Moderate COPD.

American Journal of Respiratory and Critical Care Medicine, 2023
RATIONALE Chronic obstructive pulmonary disease (COPD) is associated with high morbidity, mortality and health care costs. Cigarette smoke is a causative factor, however not all heavy smokers develop COPD.
I. Sulaiman   +29 more
semanticscholar   +1 more source

Immunosuppression participated in complement activation-mediated inflammatory injury caused by 4-octylphenol via TLR7/IκBα/NF-κB pathway in common carp (Cyprinus carpio) gills.

Aquatic Toxicology, 2022
4-octylphenol (4-OP), a toxic estrogenic environmental pollutant, can threaten aquatic animal and human health. However, toxic effect of 4-OP on fish has not been reported.
Qi Sun   +5 more
semanticscholar   +1 more source

Baicalin ameliorates Mycoplasma gallisepticum-induced inflammatory injury in the chicken lung through regulating the intestinal microbiota and phenylalanine metabolism.

Food & Function, 2021
Baicalin shows excellent protective effects against Mycoplasma gallisepticum (MG) induced inflammatory injury as discussed in our previous studies. However, the physiological effects of baicalin are notable in contrast to its low bioavailability, and the
Jian Wang, Muhammad Ishfaq, Jichang Li
semanticscholar   +1 more source

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