Results 291 to 300 of about 5,026,038 (351)

Effect of Human Periodontal Ligament Stem Cell-Derived Extracellular Vesicles on Macrophage Pyroptosis and Periodontal Inflammatory Injury in Periodontitis

Cells Tissues Organs, 2021
Periodontitis is an inflammatory disease resulting from subgingival microorganisms. Human periodontal ligament stem cells (hPDLSCs) can be applied in periodontal tissue regeneration.
Xiaole Han, Hong-min Chen, Caifang Li
semanticscholar   +1 more source

Dietary selenomethionine ameliorates lipopolysaccharide-induced renal inflammatory injury in broilers via regulating the PI3K/AKT pathway to inhibit necroptosis.

Food & Function, 2021
Selenomethionine (SeMet) has antioxidant and anti-inflammatory effects, as a widely used organic Se source in food supplements, and its inhibitory effect on the prevention and treatment of renal inflammatory injury is unclear.
Yue Zhang, Xue Qi, Xiaoming Chen, Jinxi Zhang, Wenyue Zhang, Hongjin Lin   +5 more
semanticscholar   +1 more source

Inflammatory Mediators and Intestinal Injury

Clinics in Perinatology, 1994
Although the causes of necrotizing enterocolitis (NEC) are not well understood, there is compelling evidence to suggest that the inflammatory mediators play an important role in the pathophysiology of the disease. This article examines the role of platelet-activating factor (PAF) and other mediators on the development of NEC, and attempts to explain ...
M S, Caplan, W, MacKendrick
openaire   +2 more sources

Cytokine-Induced Inflammatory Liver Injuries

Current Molecular Medicine, 2003
IL-18 is a pleiotropic cytokine and is produced by various types of cells including activated macrophages, particularly Kupffer cells. IL-18 has potential to activate inflammatory responses through induction of IFN-gamma production in collaboration with IL-12.
H, Tsutsui, K, Adachi, E, Seki, K, Nakanishi   +3 more
openaire   +2 more sources

Inflammatory Mediators in Smoke Inhalation Injury

Inflammation & Allergy-Drug Targets, 2009
Smoke inhalation occurs in 10% to 30% of patients admitted to burn centers, and increases mortality by a maximum of 20% over that predicted by age and extent of cutaneous burn alone. Pneumonia in these patients then further increases mortality by a maximum of 40%.
James B, Sterner, Thomas B, Zanders, Michael J, Morris, Leopoldo C, Cancio   +3 more
openaire   +2 more sources

Closed head injury—an inflammatory disease?

Brain Research Reviews, 2005
Closed head injury (CHI) remains the leading cause of death and persisting neurological impairment in young individuals in industrialized nations. Research efforts in the past years have brought evidence that the intracranial inflammatory response in the injured brain contributes to the neuropathological sequelae which are, in large part, responsible ...
Oliver I, Schmidt, Christoph E, Heyde, Wolfgang, Ertel, Philip F, Stahel   +3 more
openaire   +2 more sources

Baicalin attenuates lipopolysaccharide-induced intestinal inflammatory injury via suppressing PARP1-mediated NF-κB and NLRP3 signalling pathway.

Toxicon
Bacterial lipopolysaccharide (LPS) exposure is a key inducer of intestinal inflammatory injury in weaned piglets, resulting in decreased growth performance of pigs and causing severe economic losses to the swine industry; however, the mechanism of ...
Qirong Lu, Nan Wang, Defeng Wen, Pu Guo, Yu Liu, S. Fu, Chun Ye, Zhongyuan Wu, Yinsheng Qiu   +8 more
semanticscholar   +1 more source

Research on acute lung injury inflammatory network

Int. Journal of Clinical Pharmacology and Therapeutics, 2023
Acute lung injury (ALI) is a systemic inflammatory response syndrome in the lungs, with a high incidence and fatality rate of 30 - 40%. Despite the abundance of research on the pathogenesis of lung injury and the great progress that has been achieved, the various number of cells, cytokines and inflammatory response pathways involved in the pathogenesis
Yaru, Li, Yanan, Jiang, Hui, Zhang, Juan, Zhang, Junbing, Ma, Zheng, Yang, Min, Qiu, Jing, Wang   +7 more
openaire   +2 more sources

Rhein attenuates renal inflammatory injury of uric acid nephropathy via lincRNA-Cox2/miR-150-5p/STAT1 axis.

International Immunopharmacology, 2020
Rhein has protective effect on uric acid nephropathy (UAN). This article aims to demystify the mechanism of function of rhein in UAN. Mouse kidney epithelial cell line (TCMK-1) was incubated with uric acid (UA) to induce inflammatory injury.
Jiacai Hu, Zhijie Yang, Hao Wu, Daochun Wang   +3 more
semanticscholar   +1 more source

Hydrogen sulfide exposure triggers chicken trachea inflammatory injury through oxidative stress-mediated FOS/IL8 signaling.

Journal of Hazardous Materials, 2019
Hydrogen sulfide (H2S) is well known to cause irritation and damage to airway following inhalation, but the mechanism by which H2S contributes to airway toxicity is unclear. In order to assess the respiratory toxicity of H2S inhalation in chicken trachea,
Menghao Chen, Xiaojing Li, Qunxiang Shi, Ziwei Zhang, Shiwen Xu   +4 more
semanticscholar   +1 more source