Results 71 to 80 of about 1,347,839 (304)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diagnostic role of inflammatory markers in patients with brucella

Medicine Science
Systemic inflammation plays a significant role in the initiation and advancement of chronic diseases. This study aimed to evaluate the prognostic utility of these indices in patients with brucellosis.
Filiz Kurklu Bozkir, Huseyin Erdal, Seval Sonmez Yildirim   +2 more
doaj   +1 more source

The inflammatory and hemostatic cardiovascular risk markers during acute hyperglycemic crisis in type 1 and type 2 diabetes [PDF]

Journal of Medical Biochemistry, 2019
Background: We analyzed cardiovascular inflammatory (Creactive protein (CRP), interleukin 6 (IL-6)), haemostatic (homocysteine) risk markers in lean and obese patients at admission and acute hyperglicemic crisis (AHC) resolving, involving diabetic ...
Popović Dragana, Lalić Katarina, Jotić Aleksandra, Miličić Tanja, Bogdanović Jelena, Đorđević Maja, Stanković Sanja, Jeremić Veljko, Lalić Nebojša M.   +8 more
doaj  

Diagnostic and Prognostic Significance of Inflammatory Markers in Lung Cancer-Associated Pleural Effusions

The International Journal of Biological Markers, 2010
Besides massive expression in inflammatory pleural effusions, inflammatory markers are also present in cancer-induced pleural effusions. Recent advances in cancer biology point to a role of inflammatory signaling in cancer and encourage reconsidering the
Jaromír Kotyza, David Havel, Jindra Vrzalová, Vlastimil Kulda, Miloš Pešek   +4 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Night work and inflammatory markers

Indian Journal of Occupational and Environmental Medicine, 2011
Various adverse health effects associated with shift work have been documented in the medical literature. These include increased risk of cardiovascular disorders, cerebrovascular disorders, and mortality. Sleep deprivation has been shown to be associated with an elevation in inflammatory makers such as interleukin 6 (IL-6), tumor necrosis factor-alpha
Khosro, Sadeghniiat, Alireza, Safaiyan, Omid, Aminian, Forough, Sharifi   +3 more
openaire   +3 more sources

Inflammatory Markers Associated With Subclinical Coronary Artery Disease: The Multicenter AIDS Cohort Study. [PDF]

, 2016
BackgroundDespite evidence for higher risk of coronary artery disease among HIV+ individuals, the underlying mechanisms are not well understood. We investigated associations of inflammatory markers with subclinical coronary artery disease in 923 ...
Bahrami, Hossein, Budoff, Matthew, Haberlen, Sabina A, Ketlogetswe, Kerunne, Kingsley, Lawrence, McConnell, Michael V, Palella, Frank, Post, Wendy S, Rezaeian, Pantea, Tracy, Russell, Witt, Mallory D   +10 more
core   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Inflammatory markers in COVID19, are they really specific? / Inflammatory markers in COVID19

Indian Heart Journal, 2021
Deepanjan Bhattacharya, Vishwanatha Kartik Sambaturu, Kurup K.N. Harikrishnan, V.K. Ajitkumar   +3 more
doaj   +1 more source

Inflammatory Markers in Primary Aldosteronism

Physiological Research, 2016
Primary aldosteronism (PA) is the most common cause of endocrine hypertension with a high frequency of cardiovascular complications. The unfavorable cardiometabolic profile may be due to aldosterone-mediated activation of inflammatory cells, circulatory cytokines and activation of collagen synthesis in the vessel wall.
Z, Šomlóová, O, Petrák, J, Rosa, B, Štrauch, T, Indra, T, Zelinka, M, Haluzík, V, Zikán, R, Holaj, J, Widimský   +9 more
openaire   +2 more sources