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Role of Resolvins in Inflammatory and Neuropathic Pain
Pharmaceuticals, 2023 Chronic pain is an unpleasant experience associated with actual or potential tissue damage. Inflammatory pain alerts the body to inflammation and promotes healing; however, unresolved inflammation can lead to chronic pain.
Jaeik Park +5 more
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Effects and Mechanisms of Wrist-Ankle Acupuncture on Inflammatory Pain in the Rat Gastrocnemius Muscle [PDF]
Journal of Pain ResearchTingting Mai,1,* Mengcheng Cai,1,* Yuhan Tian,1,* Lanyu Jiang,1 Fanfu Fang,1 Wei Gu2 1Department of Rehabilitation Medicine, The First Affiliated Hospital of Naval Medical University, Shanghai, People’s Republic of China; 2School ...
Mai T +5 more
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Microglial Epigenetic Memory is Associated with Accelerated Resolution of Inflammatory Pain Induced by Prophylactic Macrophage-Derived Small Extracellular Vesicles [PDF]
Journal of Inflammation ResearchXuan Luo,1 Jason R Wickman,1 Jason T DaCunza,1 Yuzhen Tian,1 Ahmet Sacan,2 Seena K Ajit11Department of Pharmacology & Physiology, Drexel University College of Medicine, Philadelphia, PA, USA; 2School of Biomedical Engineering, Science & Health ...
Luo X +5 more
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Frontiers in Bioscience-Landmark, 2021 Tetrahydropalmatine (dl-THP) demonstrates an analgesic effect in animal models of neuropathic and inflammatory pain, however, the underlying mechanisms of its pharmacological action within the spinal cord remains unclear. Both P2X3 receptor and TRPV1 are
Yan Wang +8 more
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Molecules, 2021 Chronic pain syndromes are an important medical problem generated by various molecular, genetic, and pathophysiologic mechanisms. Back pain, neuropathic pain, and posttraumatic pain are the most important pathological processes associated with chronic ...
Natalia A. Shnayder +12 more
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Interleukin-17 as a potential therapeutic target for chronic pain
Frontiers in Immunology, 2022 Chronic pain remains to be a clinical challenge and is recognized as a major health problem with varying impacts on quality of life. Currently, the first-line therapy for chronic pain is opioids, which are often accompanied by unwanted psychoactive side ...
Xiaojuan Jiang +11 more
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Effect of palmitoylethanolamide on inflammatory and neuropathic pain in rats [PDF]
Korean Journal of Anesthesiology, 2017 BackgroundA growing body of evidence suggests that neuroinflammation, which is characterized by infiltration of immune cells, activation of mast cells and glial cells, and production of inflammatory mediators in the peripheral and central nervous systems,
Tai-Kyung Seol +6 more
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Dimethyl Itaconate Attenuates CFA-Induced Inflammatory Pain via the NLRP3/ IL-1β Signaling Pathway
Frontiers in Pharmacology, 2022 Itaconate plays a prominent role in anti-inflammatory effects and has gradually been ushered as a promising drug candidate for treating inflammatory diseases. However, its significance and underlying mechanism for inflammatory pain remain unexplored.
Jiaqi Lin +8 more
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Antioxidants, 2022 Chronic inflammatory pain is manifested in many diseases. The potential use of molecular hydrogen (H2) as a new therapy for neurological disorders has been demonstrated.
Santiago Coral-Pérez +6 more
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Systems and Circuits Linking Chronic Pain and Circadian Rhythms
Frontiers in Neuroscience, 2021 Research over the last 20 years regarding the link between circadian rhythms and chronic pain pathology has suggested interconnected mechanisms that are not fully understood. Strong evidence for a bidirectional relationship between circadian function and
Andrew E. Warfield +2 more
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