Results 31 to 40 of about 688,075 (263)
Mechanisms of the antiplatelet and analgesic effects of dextromethorphan and its metabolites
Tzu Chi Medical Journal, 2020 Objective: In the present study, we investigated the effects of dextromethorphan (DM) and its metabolites, including dextrorphan (LK2), 3-methoxymorphinan (LK3), and 3-hydroxymorphinan (LK4), on platelet aggregationin vitro and the inflammatory pain ...
Wen-Lin Su +4 more
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Frontiers in Integrative Neuroscience, 2023 ObjectiveThis study evaluated the antihyperalgesic and anti-inflammatory effects of percutaneous vagus nerve electrical stimulation (pVNS) associated with physical exercise, i.e., swimming, in mice with peripheral inflammation.MethodsThe pain model was ...
Aline Raulino Dutra +15 more
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Possible inflammatory pain biomarkers in postamputation pain
Scandinavian Journal of Pain, 2019 Abstract Although chronic pain after amputation is frequent, the underlying mechanisms are still not well understood. It is widely accepted that the pathogenesis of postamputation pain is multifactorial, with both peripheral and central mechanisms playing an essential role.
Buch, Nina Stockfleth +2 more
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Rapid
Molecular Pain, 2011 Background S-Nitrosylation, the reversible post-translational modification of reactive cysteine residues in proteins, has emerged as an important mechanism by which NO acts as a signaling molecule.
Lu Jingshan +4 more
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Bee Venom Acupuncture Effects on Pain and Its Mechanisms: An Updated Review
Toxins, 2021 Bee venom (BV) is a complex natural toxin that contains various pharmaceutical compounds. Bee venom acupuncture (BVA), involving a BV injection into a certain acupuncture point, has been utilized to relieve a range of pain conditions.
Soo-Hyun Sung, Gihyun Lee
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Inflammatory mediators of pain
British Journal of Anaesthesia, 1995 While sensory fibres normally respond to a range of physical and chemical stimuli their activity and metabolism are profoundly altered by a variety of mediators generated by tissue injury and inflammation. These include substances produced by damaged tissue, substances of vascular origin as well as substances released by afferent fibres themselves ...
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Frontiers in Molecular Neuroscience, 2022 Toll like receptor 9 (TLR9) is a critical sensor for danger-associated molecular patterns (DAMPs) and a crucial marker of non-sterile/sterile inflammation among all TLRs. However, the significance of TLR9 in inflammatory pain remains unclear.
Yu Chen +11 more
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How to Distinguish Non-Inflammatory from Inflammatory Pain in RA? [PDF]
Current Rheumatology ReportsSharmila Khot +2 more
exaly +2 more sources
Journal of Inflammation Research, 2021 Yucui Jiang,1,2,* Fan Ye,1,* Ying Du,1 Yingxin Zong,1 Zongxiang Tang1 1School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, People’s Republic of China; 2School of Chinese Medicine & School ...
Jiang Y, Ye F, Du Y, Zong Y, Tang Z
doaj
The transient receptor potential channels in rheumatoid arthritis: Need to pay more attention
Frontiers in Immunology, 2023 Rheumatoid arthritis (RA) is characterized by the augment of vascular permeability, increased inflammatory cells infiltration, dysregulated immune cells activation, pannus formation and unbearable pain hyperalgesia.
Mengwen Niu +4 more
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