Results 11 to 20 of about 688,075 (263)
Antioxidants, 2022 Chronic inflammatory pain is manifested in many diseases. The potential use of molecular hydrogen (H2) as a new therapy for neurological disorders has been demonstrated.
Santiago Coral-Pérez +6 more
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Systems and Circuits Linking Chronic Pain and Circadian Rhythms
Frontiers in Neuroscience, 2021 Research over the last 20 years regarding the link between circadian rhythms and chronic pain pathology has suggested interconnected mechanisms that are not fully understood. Strong evidence for a bidirectional relationship between circadian function and
Andrew E. Warfield +2 more
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Rab27a Contributes to the Processing of Inflammatory Pain in Mice
Cells, 2020 Tissue injury and inflammation may result in chronic pain, a severe debilitating disease that is associated with great impairment of quality of life. An increasing body of evidence indicates that members of the Rab family of small GTPases contribute to ...
Tilman Gross +8 more
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Pharmaceutics, 2022 Our previous studies have revealed the ultrasmall superparamagnetic iron oxide in the amine group USPIO-101 has an analgesic effect on inflammatory pain.
Guan-Ling Lu +3 more
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Biomedicines, 2023 The lateral habenula (LHb) and the ventral tegmental area (VTA), which form interconnected circuits, have important roles in the crucial control of sensory and cognitive motifs.
Mobina Alemi +5 more
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GPER involvement in inflammatory pain
Steroids, 2023 Chronic pain is a worldwide refractory health disease that causes major financial and emotional burdens and that is devastating for individuals and society. One primary source of pain is inflammation. Current treatments for inflammatory pain are weakly effective, although they usually replace analgesics, such as opioids and non-steroidal anti ...
Jouffre, Baptiste +4 more
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Efficacy of Essential Oils in Pain: A Systematic Review and Meta-Analysis of Preclinical Evidence
Frontiers in Pharmacology, 2021 Background: The demand for essential oils (EOs) has been steadily growing over the years. This is mirrored by a substantial increase in research concerned with EOs also in the field of inflammatory and neuropathic pain.
Damiana Scuteri +11 more
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Nociceptive TRP Channels: Sensory Detectors and Transducers in Multiple Pain Pathologies
Pharmaceuticals, 2016 Specialized receptors belonging to the transient receptor potential (TRP) family of ligand-gated ion channels constitute the critical detectors and transducers of pain-causing stimuli.
Aaron D. Mickle +2 more
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Preclinical Assessment of Inflammatory Pain [PDF]
CNS Neuroscience & Therapeutics, 2015 SummaryWhile acute inflammation is a natural physiological response to tissue injury or infection, chronic inflammation is maladaptive and engenders a considerable amount of adverse pain. The chemical mediators responsible for tissue inflammation act on nociceptive nerve endings to lower neuronal excitation threshold and sensitize afferent firing rate ...
Milind M, Muley +2 more
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Molecular Pain, 2011 Oncostatin M (OSM) is a member of the interleukin-6 cytokine family and regulates eg. gene activation, cell survival, proliferation and differentiation. OSM binds to a receptor complex consisting of the ubiquitously expressed signal transducer gp130 and ...
Langeslag Michiel +5 more
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