Results 41 to 50 of about 2,640,164 (297)
Peripheral opioids in inflammatory pain [PDF]
Archives of Disease in Childhood, 2004 Topically applied opioids have provided effective analgesia without adverse effects, including tolerance, in adult patients with painful inflammatory conditions. The presumed mechanism of action is by interaction with opioid receptors which are sited on sensory nerve terminals and which may be up-regulated in inflammation.
G, Watterson, R, Howard, A, Goldman
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Inflammatory Models of Pain and Hyperalgesia [PDF]
ILAR Journal, 1999 This article addresses important pain research models in nonhuman animals. These models attempt to mimic human persistent pain conditions. Models of persistent pain employ inflammatory agents that produce discomfort and hyperalgesia (i.e., an enhanced response to a noxious stimulus).
Ke, Ren, Ronald, Dubner
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Non-specific abdominal pain and air pollution: a novel association. [PDF]
, 2012 We studied whether short-term exposure to air pollution was associated with non-specific abdominal pain in epidemiologic and animal studies. Patients visiting the emergency department with non-specific abdominal pain were identified in Edmonton (1992 to
Kaplan, Gilaad G. +26 more
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Inflammatory mediators of pain
British Journal of Anaesthesia, 1995 While sensory fibres normally respond to a range of physical and chemical stimuli their activity and metabolism are profoundly altered by a variety of mediators generated by tissue injury and inflammation. These include substances produced by damaged tissue, substances of vascular origin as well as substances released by afferent fibres themselves ...
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Rapid
Molecular Pain, 2011 Background S-Nitrosylation, the reversible post-translational modification of reactive cysteine residues in proteins, has emerged as an important mechanism by which NO acts as a signaling molecule.
Lu Jingshan +4 more
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Possible inflammatory pain biomarkers in postamputation pain
Scandinavian Journal of Pain, 2019 Abstract Although chronic pain after amputation is frequent, the underlying mechanisms are still not well understood. It is widely accepted that the pathogenesis of postamputation pain is multifactorial, with both peripheral and central mechanisms playing an essential role.
Buch, Nina Stockfleth +2 more
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Mechanisms of the antiplatelet and analgesic effects of dextromethorphan and its metabolites
Tzu Chi Medical Journal, 2020 Objective: In the present study, we investigated the effects of dextromethorphan (DM) and its metabolites, including dextrorphan (LK2), 3-methoxymorphinan (LK3), and 3-hydroxymorphinan (LK4), on platelet aggregationin vitro and the inflammatory pain ...
Wen-Lin Su +4 more
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Frontiers in Integrative Neuroscience, 2023 ObjectiveThis study evaluated the antihyperalgesic and anti-inflammatory effects of percutaneous vagus nerve electrical stimulation (pVNS) associated with physical exercise, i.e., swimming, in mice with peripheral inflammation.MethodsThe pain model was ...
Aline Raulino Dutra +15 more
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, 2022 Heat shock protein 90 (Hsp90) is a ubiquitously expressed integral cellular protein essential for regulating proteomic stress. Previous research has shown that Hsp90 regulates critical signaling pathways underlying chronic pain and inflammation.
김신형
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Bee Venom Acupuncture Effects on Pain and Its Mechanisms: An Updated Review
Toxins, 2021 Bee venom (BV) is a complex natural toxin that contains various pharmaceutical compounds. Bee venom acupuncture (BVA), involving a BV injection into a certain acupuncture point, has been utilized to relieve a range of pain conditions.
Soo-Hyun Sung, Gihyun Lee
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