Results 51 to 60 of about 2,640,164 (297)

Neuronal toll like receptor 9 contributes to complete Freund’s adjuvant-induced inflammatory pain in mice

open access: yesFrontiers in Molecular Neuroscience, 2022
Toll like receptor 9 (TLR9) is a critical sensor for danger-associated molecular patterns (DAMPs) and a crucial marker of non-sterile/sterile inflammation among all TLRs. However, the significance of TLR9 in inflammatory pain remains unclear.
Yu Chen   +11 more
doaj   +1 more source

BKCa channels expressed in sensory neurons modulate inflammatory pain in mice

open access: yes, 2022
S.556-565Summary: The in vivo function of large conductance calcium‐activated potassium channels in sensory neurons includes control of inflammatory pain, but not of acute nociceptive or nerve injury‐induced neuropathic pain.
Ruth, P.   +9 more
core   +1 more source

Mechanisms involved in chronic neuropathic pain after avulsion injury [PDF]

open access: yes, 2010
PhDMotor vehicle accidents are the most common cause of injuries involving avulsion of spinal roots from the brachial or lumbosacral plexuses. This results in chronic intractable pain that is refractory to pharmacotherapy.
Chew, Daniel John
core   +4 more sources

P2X7R in Mast Cells is a Potential Target for Salicylic Acid and Aspirin in Treatment of Inflammatory Pain

open access: yesJournal of Inflammation Research, 2021
Yucui Jiang,1,2,* Fan Ye,1,* Ying Du,1 Yingxin Zong,1 Zongxiang Tang1 1School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, People’s Republic of China; 2School of Chinese Medicine & School ...
Jiang Y, Ye F, Du Y, Zong Y, Tang Z
doaj  

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Human psychophysiological responses to visceral and somatic pain – the development of integrated, reproducible human pain phenotypes [PDF]

open access: yes, 2011
PhDBackground Pain is the ubiquitous human experience, yet displays considerable inter- and intraindividual variability in health and disease. Many factors have been proposed to account for these differences.
Farmer, Adam Donald
core   +4 more sources

Implications of a local overproduction of tumor necrosis factor-α in complex regional pain syndrome [PDF]

open access: yes, 2011
Objective. To review the implications of a local overproduction of tumor necrosis factor-α for the pathogenesis and treatment of complex regional pain syndrome. Background.
Walker, S., Drummond, P.D.
core  

TOIB Study. Are topical or oral ibuprofen equally effective for the treatment of chronic knee pain presenting in primary care: A randomised controlled trial with patient preference study. [ISRCTN79353052] [PDF]

open access: yes, 2005
Background: Many older people have chronic knee pain. Both topical and oral non- steroidal anti-inflammatory drugs (NSAIDs) are commonly used to treat this.
Spencer, Anne E.   +33 more
core   +2 more sources

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi   +9 more
wiley   +1 more source

The transient receptor potential channels in rheumatoid arthritis: Need to pay more attention

open access: yesFrontiers in Immunology, 2023
Rheumatoid arthritis (RA) is characterized by the augment of vascular permeability, increased inflammatory cells infiltration, dysregulated immune cells activation, pannus formation and unbearable pain hyperalgesia.
Mengwen Niu   +4 more
doaj   +1 more source

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