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Pain and inflammatory bowel disease [PDF]
Inflammatory Bowel Diseases, 2009 Abdominal pain is a common symptom of inflammatory bowel disease (IBD: Crohn's disease, ulcerative colitis). Pain may arise from different mechanisms, which can include partial blockage and gut distention as well as severe intestinal inflammation. A majority of patients suffering from acute flares of IBD will experience pain, which will typically ...
Klaus, Bielefeldt +2 more
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The British Journal of Radiology, 1991 A 57-year-old male was admitted as an emergency with a 3 day history of thirst, frequency and severe low back pain radiating to his right flank for 24 h. He was apyrexial and examination was normal. An elevated plasma glucose confirmed late onset diabetes. Urinalysis did not show any evidence of infection.
S A, Renowden, M W, Hayward
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Biomedicines, 2022 Neuropathic pain is often closely associated with nerve injury or inflammation, and the role of traditional nonsteroidal anti-inflammatory drugs as adjuvants for treating chemotherapy-induced peripheral neuropathic pain remains unclear.
Yurong Ma +6 more
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Peripheral opioids in inflammatory pain [PDF]
Archives of Disease in Childhood, 2004 Topically applied opioids have provided effective analgesia without adverse effects, including tolerance, in adult patients with painful inflammatory conditions. The presumed mechanism of action is by interaction with opioid receptors which are sited on sensory nerve terminals and which may be up-regulated in inflammation.
G, Watterson, R, Howard, A, Goldman
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Brain and Behavior, 2023 Background Premature infants are inevitably exposed to painful events, including repetitive procedures, inflammation, or mixed stimulation that may induce long‐term behavioral outcomes.
Ru Ling +6 more
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Neuropeptide Y-expressing dorsal horn inhibitory interneurons gate spinal pain and itch signalling
eLife, 2023 Somatosensory information is processed by a complex network of interneurons in the spinal dorsal horn. It has been reported that inhibitory interneurons that express neuropeptide Y (NPY), either permanently or during development, suppress mechanical itch,
Kieran A Boyle +12 more
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Journal of Pain Research, 2021 Marcio Carneiro Vieira,1,2 Fernanda Bezerra de Mello Monte,3 Bruno Eduardo Dematte,3 Tadeu Lima Montagnoli,3 Guilherme Carneiro Montes,3 Jaqueline Soares da Silva,3 Rosalia Mendez-Otero,4 Margarete Manhães Trachez,3 Roberto Takashi Sudo,1,3 Gisele
Vieira M C +9 more
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Phα1β Spider Toxin Reverses Glial Structural Plasticity Upon Peripheral Inflammation
Frontiers in Cellular Neuroscience, 2019 The incoming signals from injured sensory neurons upon peripheral inflammation are processed in the dorsal horn of spinal cord, where glial cells accumulate and play a critical role in initiating allodynia (increased pain in response to light-touch ...
Helia Tenza-Ferrer +7 more
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Identification of Glycine Receptor α3 as a Colchicine-Binding Protein
Frontiers in Pharmacology, 2018 Colchicine (Col) is considered a kind of highly effective alkaloid for preventing and treating acute gout attacks (flares). However, little is known about the underlying mechanism of Col in pain treatment.
Xikun Zhou +15 more
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Inflammatory Models of Pain and Hyperalgesia [PDF]
ILAR Journal, 1999 This article addresses important pain research models in nonhuman animals. These models attempt to mimic human persistent pain conditions. Models of persistent pain employ inflammatory agents that produce discomfort and hyperalgesia (i.e., an enhanced response to a noxious stimulus).
Ke, Ren, Ronald, Dubner
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