Results 41 to 50 of about 9,035,830 (338)

Avian Influenza & Human Health

, 2014
The world is now under human pandemic threat by avian influenza viruses. As the human, animal and the environment interact closely from the dawn of the civilization, human health is tremendously influenced by animal health and their health issues.
Prosun Roy, S. Islam, F. Rahman, M. R. Siddiqui   +3 more
semanticscholar   +1 more source

Characterization of orally efficacious influenza drug with high resistance barrier in ferrets and human airway epithelia

Science Translational Medicine, 2019
A next-generation, broad-spectrum, orally efficacious influenza A and B virus inhibitor is associated with a high genetic resistance barrier. Treating flu, escaping resistance Influenza viruses can cause severe illness and death.
M. Toots, Jeong-Joong Yoon, R. Cox, M. Hart, Zachary M. Sticher, Negar Makhsous, R. Plesker, Alec H Barrena, Prabhakar Reddy, Deborah G. Mitchell, Ryan C. Shean, Gregory R. Bluemling, A. Kolykhalov, A. Greninger, M. Natchus, G. Painter, Richard K. Plemper   +16 more
semanticscholar   +1 more source

Insights into Genetic Characteristics and Virological Features of Endemic Avian Influenza A (H9N2) Viruses in Egypt from 2017–2021

Viruses, 2022
From 2010 to 2013, genotype I avian influenza A(H9N2) viruses of the G1-lineage were isolated from several poultry species in Egypt. In 2014, novel reassortant H9N2 viruses were detected in pigeons designated as genotype II.
Mohamed El Sayes, Ahmed Kandeil, Yassmin Moatasim, Ahmed El Taweel, Adam Rubrum, Omnia Kutkat, Mina Nabil Kamel, Rebecca Badra, Ahmed B. Barakat, Pamela P. McKenzie, Rabeh El-Shesheny, Richard J. Webby, Ghazi Kayali, Mohamed Ahmed Ali   +13 more
doaj   +1 more source

The role of platelets in mediating a response to human influenza infection

Nature Communications, 2019
Influenza infection increases the incidence of myocardial infarction but the reason is unknown. Platelets mediate vascular occlusion through thrombotic functions but are also recognized to have immunomodulatory activity.
Milka Koupenova, Heather A. Corkrey, O. Vitseva, Giorgia Manni, Catherine J. Pang, L. Clancy, C. Yao, J. Rade, D. Levy, Jennifer P. Wang, R. Finberg, E. Kurt-Jones, J. Freedman   +12 more
semanticscholar   +1 more source

Broadly protective human antibodies that target the active site of influenza virus neuraminidase

Science, 2019
Alternative influenza target There is a pressing need for a broadly protective influenza vaccine that can neutralize this constantly varying, deadly virus. Stadlbauer et al.
D. Stadlbauer, Xueyong Zhu, Meagan McMahon, J. Turner, Teddy J. Wohlbold, A. Schmitz, Shirin Strohmeier, Wenli Yu, Raffael Nachbagauer, P. Mudd, I. Wilson, A. Ellebedy, F. Krammer   +12 more
semanticscholar   +1 more source

Survival of influenza virus on human fingers [PDF]

Clinical Microbiology and Infection, 2014
Indirect transmission of the influenza virus via finger contamination with respiratory mucus droplets has been hypothesized to contribute to transmission in the community. Under laboratory conditions, influenza-infected respiratory droplets were reconstituted as close as possible to natural conditions.
Thomas, Y, Boquete-Suter, P, Koch, D, Pittet, Didier, Kaiser, Laurent   +4 more
openaire   +3 more sources

Influenza research database: an integrated bioinformatics resource for influenza research and surveillance. [PDF]

, 2012
BackgroundThe recent emergence of the 2009 pandemic influenza A/H1N1 virus has highlighted the value of free and open access to influenza virus genome sequence data integrated with information about other important virus characteristics.DesignThe ...
Baumgarth, Nicole, Deitrich, Jon, García-Sastre, Adolfo, Hunt, Victoria, Klem, Edward, Kumar, Sanjeev, Larsen, Christopher N, Macken, Catherine, Noronha, Jyothi, Pickett, Brett E, Ramsey, Alvin, Scheuermann, Richard H, Squires, R Burke, Suarez, David, Zaremba, Sam, Zhang, Yun, Zhou, Liwei   +16 more
core   +1 more source

Potent Antiviral Activity of Vitamin B12 against Severe Acute Respiratory Syndrome Coronavirus 2, Middle East Respiratory Syndrome Coronavirus, and Human Coronavirus 229E

Microorganisms, 2023
Repurposing vitamins as antiviral supporting agents is a rapid approach used to control emerging viral infections. Although there is considerable evidence supporting the use of vitamin supplementation in viral infections, including severe acute ...
Yassmin Moatasim, Omnia Kutkat, Ahmed M. Osman, Mokhtar R. Gomaa, Faten Okda, Mohamed El Sayes, Mina Nabil Kamel, Mohamed Gaballah, Ahmed Mostafa, Rabeh El-Shesheny, Ghazi Kayali, Mohamed A. Ali, Ahmed Kandeil   +12 more
doaj   +1 more source

Results from the centers for disease control and prevention's predict the 2013-2014 Influenza Season Challenge [PDF]

, 2016
Background: Early insights into the timing of the start, peak, and intensity of the influenza season could be useful in planning influenza prevention and control activities.
Allen, Christopher, Alper, David, Aman, Susan, Anil Kumar, V. S., Aslam, Anoshã, Bakach, Iurii, Barrett, Chris, BASAGNI, Stefano, Biggerstaff, Matthew, Bisset, Keith, Broniatowski, David, Brooks, Logan, Brownstein, John S., Butler, Patrick, Chakraborty, Prithwish, Chandra, Priyadarshini, Chen, Jiangzhuo, Del Valle, Sara Y., Deshpande, Alina, Dredze, Mark, Eggo, Rosalind, Eubank, Stephen, Fairchild, Geoffrey, Farrow, David, Finelli, Lyn, Fox, Spencer, Fung, Isaac Chun Hai, Gambhir, Manoj, Generous, Nicholas, GESUALDO, Francesco, Goldstein, Ed, Hao, Yi, Henderson, Jette, Hickman, Kyle S., Hickmann, Kyle S., Hyman, James M., Hyun, Sangwon, Karspeck, Alicia, Kaup, Hemchandra, Khadivi, Pejman, Krishnan, Ramesh, Laskowski, Kathy, Lewis, Bryan, Lipsitch, Marc, Lum, Kristian, Madhavan, Satish, Marathe, Madhav, Markar, Ashirwad, Mekaru, Sumiko R., Meyers, Lauren Ancel, Nagel, Anna, Nsoesie, Elaine O., Pashley, Bryanne, Paul, Michael, PERRA, NICOLA, Priedhorsky, Reid, Ramakrishnan, Anurekha, Ramakrishnan, Naren, Rosenfeld, Roni, Scarpino, Sam, Schaible, Braydon J., Scott, James, Sexton, Jessica K., Shaman, Jeffrey, Singh, Bismark, Srinivasan, Ravi, STILO, GIOVANNI, Tibshirani, Ryan J., Tozzi, Alberto E., Tse, Zion Tsz Ho, Tsou, Ming Hsiang, VELARDI, Paola, Vespignani, Alessandro, Yang, Wan, Ying, Yuchen, Zhang, Qian   +75 more
core   +1 more source

Polymer-stabilized sialylated nanoparticles : synthesis, optimization, and differential binding to influenza hemagglutinins [PDF]

, 2020
During influenza infection, hemagglutinins (HAs) on the viral surface bind to sialic acids on the host cell's surface. While all HAs bind sialic acids, human influenza targets terminal α2,6 sialic acids and avian influenza targets α2,3 sialic acids.
Baker, Alexander, Gibson, Matthew I., Richards, Sarah-Jane, Walker, Marc   +3 more
core   +2 more sources