Results 41 to 50 of about 9,115,931 (294)

Viruses associated with pneumonia in adults. [PDF]

, 2012
Viral pneumonia, which is typically associated with disease in childhood, is increasingly recognized as causing problems in adults. Certain viruses, such as influenza virus, can attack fully immunocompetent adults, but many viruses take advantage of more-
Cesario, Thomas C
core   +1 more source

Differentiated human airway organoids to assess infectivity of emerging influenza virus

Proceedings of the National Academy of Sciences of the United States of America, 2018
Significance Influenza virus infection represents a major threat to public health worldwide. There is no biologically relevant, reproducible, and readily available in vitro model for predicting the infectivity of influenza viruses in humans. Based on the
Jie Zhou, Cun Li, Norman Sachs, M. Chiu, Bosco Ho-Yin Wong, Hin Chu, V. Poon, Dong Wang, Xiaoyu Zhao, Lei Wen, Wenjun Song, Shuofeng Yuan, K. K. Wong, J. Chan, K. To, Honglin Chen, H. Clevers, K. Yuen   +17 more
semanticscholar   +1 more source

Analysis of influenza-like illness trends in Saudi Arabia: a comparative study of statistical and deep learning techniques [PDF]

Osong Public Health and Research Perspectives
Objectives To develop and evaluate forecasting models using the Holt-Winters statistical approach and the long short-term memory (LSTM) deep learning method for weekly seasonal influenza-like illness (ILI) incidences in Saudi Arabia.
Fathelrhman EL Guma
doaj   +1 more source

Robust antiviral activity of commonly prescribed antidepressants against emerging coronaviruses: in vitro and in silico drug repurposing studies

Scientific Reports, 2022
During the current coronavirus disease 2019 (COVID-19) pandemic, symptoms of depression are commonly documented among both symptomatic and asymptomatic quarantined COVID-19 patients.
Omnia Kutkat, Yassmin Moatasim, Ahmed A. Al‐Karmalawy, Hamada S. Abulkhair, Mokhtar R. Gomaa, Ahmed N. El-Taweel, Noura M. Abo Shama, Mohamed GabAllah, Dina B. Mahmoud, Ghazi Kayali, Mohamed A. Ali, Ahmed Kandeil, Ahmed Mostafa   +12 more
doaj   +1 more source

Design and Immunological Properties of the Novel Subunit Virus-like Vaccine against SARS-CoV-2

Vaccines, 2022
The COVID-19 pandemic is ongoing, and the need for safe and effective vaccines to prevent infection and to control spread of the virus remains urgent. Here, we report the development of a SARS-CoV-2 subunit vaccine candidate (Betuvax-CoV-2) based on RBD ...
Igor V. Krasilnikov, Aleksandr V. Kudriavtsev, Anna V. Vakhrusheva, Maria E. Frolova, Aleksandr V. Ivanov, Marina A. Stukova, Ekaterina A. Romanovskaya-Romanko, Kirill A. Vasilyev, Nataliya V. Mushenkova, Artur A. Isaev   +9 more
doaj   +1 more source

The Future of Flu: A Review of the Human Challenge Model and Systems Biology for Advancement of Influenza Vaccinology

Frontiers in Cellular and Infection Microbiology, 2019
Objectives: Novel approaches to advance the field of vaccinology must be investigated, and are particularly of importance for influenza in order to produce a more effective vaccine.
A. Sherman, A. Mehta, Neal W. Dickert, E. Anderson, Nadine G. Rouphael   +4 more
semanticscholar   +1 more source

Global Distribution and Molecular Evolution of Bat Coronaviruses

Zoonotic Diseases
Bat coronaviruses cause a wide range of illnesses in humans and animals. Bats are known to harbor a wide diversity of Alphacoronaviruses and Betacoronaviruses.
Mohamed El Sayes, Rebecca Badra, Mohamed A. Ali, Rabeh El-Shesheny, Ghazi Kayali   +4 more
doaj   +1 more source

TMPRSS2 Is the Major Activating Protease of Influenza A Virus in Primary Human Airway Cells and Influenza B Virus in Human Type II Pneumocytes

Journal of Virology, 2019
Influenza A viruses (IAV) and influenza B viruses (IBV) cause significant morbidity and mortality during seasonal outbreaks. Cleavage of the viral surface glycoprotein hemagglutinin (HA) by host proteases is a prerequisite for membrane fusion and ...
H. Limburg, Anne Harbig, Dorothea Bestle, D. A. Stein, H. Moulton, J. Jaeger, Harshavardhan Janga, Kornelia Hardes, J. Koepke, Leon N. Schulte, A. Koczulla, B. Schmeck, H. Klenk, E. Böttcher-Friebertshäuser   +13 more
semanticscholar   +1 more source

Transmission dynamics of avian influenza viruses in Egyptian poultry markets

npj Viruses
Live bird markets (LBMs) are considered hotspots for Avian Influenza Viruses (AIVs). In such markets, AIVs pose threats to both poultry and public health.
Sara H. Mahmoud, Mokhtar Gomaa, Ahmed El Taweel, Yassmin Moatasim, Mina Nabil Kamel, Mohamed El Sayes, Noura M. Abo Shama, Rebecca Badra, Mona Mahmoud, Pamela P. McKenzie, Richard J. Webby, Ahmed Kandeil, Mohamed Ahmed Ali, Rabeh El-Shesheny, Ghazi Kayali   +14 more
doaj   +1 more source

Nanomolecular detection of human influenza virus type A using reverse transcription loop-mediated isothermal amplification assisted with rod-shaped gold nanoparticles [PDF]

, 2014
Reverse transcription loop-mediated isothermal amplification (RT-LAMP) and rod-shaped gold nanoparticles (gold nanorods; GNRs) were employed for nanomolecular detection of human influenza virus type A RNA.
Gill, P., Niazi, A., Nikbakht, H., Tabarraei, A.   +3 more
core   +1 more source