Results 41 to 50 of about 8,955,500 (341)

Characterization of orally efficacious influenza drug with high resistance barrier in ferrets and human airway epithelia

open access: yesScience Translational Medicine, 2019
A next-generation, broad-spectrum, orally efficacious influenza A and B virus inhibitor is associated with a high genetic resistance barrier. Treating flu, escaping resistance Influenza viruses can cause severe illness and death.
M. Toots   +16 more
semanticscholar   +1 more source

Insights into Genetic Characteristics and Virological Features of Endemic Avian Influenza A (H9N2) Viruses in Egypt from 2017–2021

open access: yesViruses, 2022
From 2010 to 2013, genotype I avian influenza A(H9N2) viruses of the G1-lineage were isolated from several poultry species in Egypt. In 2014, novel reassortant H9N2 viruses were detected in pigeons designated as genotype II.
Mohamed El Sayes   +13 more
doaj   +1 more source

The role of platelets in mediating a response to human influenza infection

open access: yesNature Communications, 2019
Influenza infection increases the incidence of myocardial infarction but the reason is unknown. Platelets mediate vascular occlusion through thrombotic functions but are also recognized to have immunomodulatory activity.
Milka Koupenova   +12 more
semanticscholar   +1 more source

Survival of influenza virus on human fingers [PDF]

open access: yesClinical Microbiology and Infection, 2014
Indirect transmission of the influenza virus via finger contamination with respiratory mucus droplets has been hypothesized to contribute to transmission in the community. Under laboratory conditions, influenza-infected respiratory droplets were reconstituted as close as possible to natural conditions.
Thomas, Y   +4 more
openaire   +3 more sources

Influenza research database: an integrated bioinformatics resource for influenza research and surveillance. [PDF]

open access: yes, 2012
BackgroundThe recent emergence of the 2009 pandemic influenza A/H1N1 virus has highlighted the value of free and open access to influenza virus genome sequence data integrated with information about other important virus characteristics.DesignThe ...
Baumgarth, Nicole   +16 more
core   +1 more source

Broadly protective human antibodies that target the active site of influenza virus neuraminidase

open access: yesScience, 2019
Alternative influenza target There is a pressing need for a broadly protective influenza vaccine that can neutralize this constantly varying, deadly virus. Stadlbauer et al.
D. Stadlbauer   +12 more
semanticscholar   +1 more source

Differentiated human airway organoids to assess infectivity of emerging influenza virus

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2018
Significance Influenza virus infection represents a major threat to public health worldwide. There is no biologically relevant, reproducible, and readily available in vitro model for predicting the infectivity of influenza viruses in humans. Based on the
Jie Zhou   +17 more
semanticscholar   +1 more source

Potent Antiviral Activity of Vitamin B12 against Severe Acute Respiratory Syndrome Coronavirus 2, Middle East Respiratory Syndrome Coronavirus, and Human Coronavirus 229E

open access: yesMicroorganisms, 2023
Repurposing vitamins as antiviral supporting agents is a rapid approach used to control emerging viral infections. Although there is considerable evidence supporting the use of vitamin supplementation in viral infections, including severe acute ...
Yassmin Moatasim   +12 more
doaj   +1 more source

Results from the centers for disease control and prevention's predict the 2013-2014 Influenza Season Challenge [PDF]

open access: yes, 2016
Background: Early insights into the timing of the start, peak, and intensity of the influenza season could be useful in planning influenza prevention and control activities.
Allen, Christopher   +75 more
core   +1 more source

The Future of Flu: A Review of the Human Challenge Model and Systems Biology for Advancement of Influenza Vaccinology

open access: yesFrontiers in Cellular and Infection Microbiology, 2019
Objectives: Novel approaches to advance the field of vaccinology must be investigated, and are particularly of importance for influenza in order to produce a more effective vaccine.
A. Sherman   +4 more
semanticscholar   +1 more source

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